Advanced
Pharmacotherapeutics
Exam 1
WHO prescribing process - CORRECT ANSWER-Define the diagnosis
Specify the treatment objective
Choose the correct therapy
Start the therapy
Educate the patient on the diagnosis and therapy
Monitor the effects
The FDA - CORRECT ANSWER-protect public health to ensure safety and efficacy, as well as
human and veterinary drugs, biological products, food and medical devices.
Pharmacodynamics - CORRECT ANSWER-What the drug does to the body
Pharmacokinetics - CORRECT ANSWER-What the body does to the drug
Four examples of pharmacokinetics - CORRECT ANSWER-Absorption
Distribution
Metabolism
Elimination
, Absorption - CORRECT ANSWER-Also called bioavailability-- The transfer of a drug from the site
of administration to the bloodstream. Mostly occurs through passive diffusion
-Effected by route, properties, surface area and contact time.
Efficacy - CORRECT ANSWER-The desired effect of the drug has been reached.
Potency - CORRECT ANSWER-Amount of drug desired to reach efficacy and cause an effect.
Volume of Distribution - CORRECT ANSWER-The amount of drug in the body, divided by the
plasma protein in the body.
Small Volume of Distribution - CORRECT ANSWER-Example: If the drug is large moleculed,
ionized and protein bound-- Smaller distribution rate because it is protein bound, large and
cannot pass through passive diffusion
Lipophillic - CORRECT ANSWER-Fat-loving drugs. Can cross barriers easily, have a high volume of
distribution, small in size and unionized.
Hydrophillic - CORRECT ANSWER-Water loving drugs- IONIZED. Do not cross the membranes
very easily, has a low vol of distribution.
Metabolism - CORRECT ANSWER-the breakdown and the inactivation of a drug.
conjugation - CORRECT ANSWER-liver making a substance water soluable in order for body to
eliminate it.
Pharmacotherapeutics
Exam 1
WHO prescribing process - CORRECT ANSWER-Define the diagnosis
Specify the treatment objective
Choose the correct therapy
Start the therapy
Educate the patient on the diagnosis and therapy
Monitor the effects
The FDA - CORRECT ANSWER-protect public health to ensure safety and efficacy, as well as
human and veterinary drugs, biological products, food and medical devices.
Pharmacodynamics - CORRECT ANSWER-What the drug does to the body
Pharmacokinetics - CORRECT ANSWER-What the body does to the drug
Four examples of pharmacokinetics - CORRECT ANSWER-Absorption
Distribution
Metabolism
Elimination
, Absorption - CORRECT ANSWER-Also called bioavailability-- The transfer of a drug from the site
of administration to the bloodstream. Mostly occurs through passive diffusion
-Effected by route, properties, surface area and contact time.
Efficacy - CORRECT ANSWER-The desired effect of the drug has been reached.
Potency - CORRECT ANSWER-Amount of drug desired to reach efficacy and cause an effect.
Volume of Distribution - CORRECT ANSWER-The amount of drug in the body, divided by the
plasma protein in the body.
Small Volume of Distribution - CORRECT ANSWER-Example: If the drug is large moleculed,
ionized and protein bound-- Smaller distribution rate because it is protein bound, large and
cannot pass through passive diffusion
Lipophillic - CORRECT ANSWER-Fat-loving drugs. Can cross barriers easily, have a high volume of
distribution, small in size and unionized.
Hydrophillic - CORRECT ANSWER-Water loving drugs- IONIZED. Do not cross the membranes
very easily, has a low vol of distribution.
Metabolism - CORRECT ANSWER-the breakdown and the inactivation of a drug.
conjugation - CORRECT ANSWER-liver making a substance water soluable in order for body to
eliminate it.
