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USMLE EXAM PREP TEST BANK VERIFIED QUESTIONS AND CORRECT ANSWERS

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USMLE EXAM PREP TEST BANK VERIFIED QUESTIONS AND CORRECT ANSWERS

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USMLE EXAM PREP TEST BANK VERIFIED
QUESTIONS AND CORRECT ANSWERS

●● clindamycin, chloramphenicol
Answer: 50 ribosome, inhibits PEPTIDYL TRANSFERASE
(incorporation of new a.a.'s into growing strand)


●● linezolid
Answer: 50S protein synthesis inhibitor


●● tetracycline
Answer: 30S ribosome, blocks tRNA-aa from binding to ACCEPTOR
SITE on mRNA


●● aminoglycosides
Answer: 30S ribosome, blocks INITIATION of translation and induces
PREMATURE TERMINATION or mistranslation


●● vancomycin
Answer: binds D-ala-D-ala portion of cell wall precursors, prevents
POLYMERIZATION OF PEPTIDOGLYCANS


●● cephalosporins

, Answer: beta-lactam, with with some resistance to penicillinase


●● ampicillin, amoxicillin
Answer: beta-lactam, broader spectrum but still susceptible to
penicillinase


●● ticarcillin, piperacillin
Answer: beta-lactam, broad-spectrum


●● rifampin
Answer: blocks mRNA transcription by inhibiting mRNA
POLYMERASE beta subunit


●● metronidazole
Answer: interacts with microbial ferredoxins to produce CYTOTOXIC
INTERMEDIATES


●● fluoroquinolones
Answer: inhibits DNA GYRASE (controls supercoiling) and
TOPOISOMERASE (untangling interlocked daughter chromosomes)


●● trimethroprim

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