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Prophecy Relias Pharmacology RN A Study Guide | 110 Practice Questions & Answers | Latest Update 2026

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Comprehensive RN Pharmacology study resource designed for focused nursing exam preparation and competency review. Includes 110 practice questions with answers covering medication administration, pharmacokinetics and pharmacodynamics, dosage calculations, safe medication practices, adverse effects, drug interactions, contraindications, nursing assessments, patient education, and clinical decision-making. Review major medication categories and strengthen your ability to apply pharmacology concepts to realistic nursing scenarios. Ideal for RN students, nursing coursework, competency preparation, and NCLEX-style practice. Updated for 2026 with an exam-focused approach to medication safety and clinical nursing knowledge. Relias Assessments evaluate role-specific clinical knowledge and critical skills, including medication administration and problem solving.

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PROPHECY RELIAS PHARMACOLOGY RN EXAM j j j j




2026/LATEST UPDATE WITH 200 QUESTIONS AND
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j CORRECT DETAILED ANSWERS /RN PHARMACOLOGY j j j j




RELIAS PROPHECY (VERIFIED ANSWERS) |ALREADY
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GRADED A+/NEWEST 2026 j j j




Which of the following medications is known to cause orange-colored
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urine? - RIGHT ANS:->>phenazopyridine (Pyridium)
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You are ordered to give digoxin. Your client's vital signs are as follows:Blood
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j Pressure 130/75, Temp 97.9 oral, HR 52, O2 Sat 100% room air. What should
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j you do next? - RIGHT ANS:->>Hold digoxin and call the provider
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Normal Saline (NS) is the solution of choice over D5W when preparing to
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administer a blood transfusion because: - RIGHT ANS:->>Normal Saline is
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j an isotonic solution and prevents cell hemolysis
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Client is to receive 5mg/kg of medication. Client weighs 80kg. How muchwould
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j you administer? - RIGHT ANS:->>400mg
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Your client taking digoxin (Lanoxin) has an AM Potassium level of 3.0.This
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j level may: - RIGHT ANS:->>Increase risk of digoxin toxicity
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The client is diagnosed with multiple myeloma. The physician has ordered
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,cyclophosphamide (Cytoxan). Which instruction should be given to the client? -
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j RIGHT ANS:->>Increase daily water intake
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Which of the following medications will crystalize when mixed with D5NS? -
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RIGHT ANS:->>phenytoin (Dilantin)
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Which of the following medications should be questioned by the caregiver, if
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ordered by the provider to treat a client's complaint of nausea and vomiting? -
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j RIGHT ANS:->>famotidine (Pepcid) j j




Your client has an epidural infusing hydromorphone with bupivacaine at 6ml/hr
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j continuously. The client's blood pressure at the beginning of yourshift was j j j j j j j j j j j




j 92/58 with a heart rate of 68. You noticed the client's blood pressures have
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j been around 130/70. What should you do FIRST? - RIGHT ANS:->>Check
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j infusion rate to confirm 6ml/hr, then notify anesthesiaprovider
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The dosage of which drug must be tapered off slowly to prevent acute
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adrenal insufficiency? - RIGHT ANS:->>prednisone (Deltasone)
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When teaching a new caregiver on how to administer IV push furosemide
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j (Lasix), you emphasize that it should be given over two minutes to avoid: -
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RIGHT ANS:->>tinnitus
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A caregiver is caring for a client with hyperparathyroidism and notes that the
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,client's serum calcium level is 13mg/dl. Which medication should the caregiver
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j prepare to administer as prescribed to the client? - RIGHT ANS:-
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>>calcintonin (Miacalcin) j




A client has a prescription to take Guaifenesin (Mucinex) every 4 hours,as
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j needed. The caregiver determines that the client understands the MOST
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effective use of the medication if the client states that he or she will: - RIGHT
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j ANS:->>take the medication with a full glass of water j j j j j j j j




Acetylsalicylic acid (Aspirin) has which of the following pharmacological j j j j j j j j




j effects? - RIGHT ANS:->>Anti-inflammatory, anti-pyretic, decrease
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Your client is to receive 2 G vancomycin over 2 hours. The medication comes in
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from the pharmacy as 2 G Vancomycin in 250ml normal saline. Atwhat rate will the
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IV medication run? - RIGHT ANS:->>125ml/hr
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Sildenafil (Viagra) is prescribedtotreat aclient with erectile dysfunction.A
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j caregiver reviews the client's medical record and would question the
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j prescription if which of the following is noted in the history? - RIGHT ANS:-
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>>Use of nitroglycerin
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, While delivering the lunch tray of a client who is taking warfarin
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j (Coumadin), the caregiver notices diversity of food items. Which of the j j j j j j j j j j




following foods would be a concern? - RIGHT ANS:->>Spinach
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Your client is receiving vancomycin (Vancocin) 500mg IV every 12 hours.As a
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j caregiver, you understand that the PRIMARY rationale for monitoring serum
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j levels of vancomycin is that: - RIGHT ANS:->>It can cause nephrotoxicity
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Convert 1.2 milligrams to micrograms - RIGHT ANS:->>1200 mcg
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You are caring for a client with diabetes. Humalog insulin is ordered viasliding
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j scale AC and HS. When is the best time to administer Humalog insulin? - RIGHT
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j ANS:->>15 minutes before meal arrives j j j j




A provider orders one liter of NS to be infused over four hours. At what ratewould
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j you set the IV pump? - RIGHT ANS:->>250ml/hr
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*WRONG* Which medication is used to treat iron toxicity? - j j j j j j j j j




RIGHT ANS:->>A) digoxin immune fab (Digibind)
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B) Naloxone (Narcan)
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j C) Mephyton (Vitamin K)
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D) *WRONG* deferoxamine (Digibind)
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