Rau’s Respiratory Care Pharmacology 11th Edition Study Guide | Practice Questions & Answers | 2026

TESTBANK v




Rau’sRespiratoryCarePharmacology
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11thEdition byDouglasGardenhire,
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AllChapters1to23Covered
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, TABLEOFCONTENTS v v




UnitI:BasicConceptsand Principles inPharmacology
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1.Introduction toRespiratoryCarePharmacology
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2.PrinciplesofDrugAction
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3.AdministrationofAerosolizedAgents
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4.CalculatingDrugDoses
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5.TheCentralandPeripheral NervousSystems
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UnitII:Drugs Used toTreat theRespiratorySystem
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6.Adrenergic(Sympathomimetic)Bronchodilators
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7.Anticholinergic(Parasympatholytic)Bronchodilators
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8.Xanthines
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9.Mucus-ControllingDrugTherapy
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10.Surfactant Agents
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11.CorticosteriodsinRespiratoryCare
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12.Nonsteroidal AntiasthmaAgents
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13.AerosolizedAntiinfectiveAgents
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14.AntimicrobialAgents
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15.Cold andCoughAgents
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16.Selected AgentsofPulmonaryValue
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17.NeonatalandPediatricAerosolizedDrugTherapy
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UnitIII:CriticalCare, Cardiovascular, and PolysomnographyAgents
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18.Skeletal MuscleRelaxants(NeuromuscularBlockingAgents)
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19.DiureticAgents
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20.DrugsAffectingtheCentral NervousSystem
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21.Vasopressors,Inotropes,andAntiarrythmicAgents
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22.DrugsAffectingCirculation:Antihypertensives,Antianginals,Antithrombotics
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23.Sleep andSleepPharmacology
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,Chapter01:IntroductiontoRespiratoryCarePharmacology Gardenhire:
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Rau’sRespiratoryCarePharmacology,11thEdition
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MULTIPLE CHOICE v




1. Whatisthename ofthereceptor sitesthat arelocatedintheperipheralvasculature, the heart,
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vbronchialmuscle, and bronchial blood vessels? v v v v v




a. Beta2receptors c. Alphareceptors
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b. Gammareceptors d. Beta 1receptors v vv v v v




ANS: C v




Alphareceptorsarelocatedintheperipheral vasculature, theheart,bronchial muscle,and
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vbronchial blood vessels. v v




PTS: 1 v v




2. Whichreceptorsiteresults intachycardia,anincreasedpotentialforarrhythmias,andan
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v increased cardiac output? v v




a. Beta1receptor c. Alphareceptor
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b. Beta2receptor d. Delta receptor
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ANS: A v




Stimulation ofthe beta-1receptorsresultsintachycardia,anincreased potential for arrhythmias,
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and anincreasedcardiacoutput.Inadministeringdrugs tothepulmonarysystem, stimulationofthe
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beta-1 sites is not desired. However, most respiratory pharmacologic agents havesome beta-1
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stimulatory effect.
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PTS: 1 v v




3. Stimulation ofthebeta2receptorscauses v v v v v v vv




a. peripheralvasoconstrictionandmild bronchoconstriction inthelungs. v v v v v v v




b. tachycardia,anincreased potentialforarrhythmias,andanincreasedcardiacoutput. v v v v v v v v v v




c. bronchodilation.
d. peripheralvasodilation,bradycardia,anddecreasedcardiacoutput. v v v v v v




ANS: C v




Stimulationofthebeta-2receptors inthelungscauses bronchodilation. v v v v v v v v v




PTS: 1 v v




4. Acetylcholinestimulates v v v




a. theVagusnerve. v v




b. theadrenergicreceptors. v v




c. thesympatheticnervoussystem. v v v




d. thecholinergicreceptors. v v




ANS: D v




Acetylcholinestimulatesthecholinergicreceptors. v v v v




PTS: 1 v v




5. Whatimmunoglobulinantibodysensitizes themastcell?
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a. Leukotrienes c. Histamine

, b. IgE d. Prostaglandins
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ANS: B v




TheIgE(reagin) antibodies sensitizethemastcell.Repeated exposuretotheantigen causesthe
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vdegranulation of themast cell. v v v v




PTS: 1 v v




6. Whichof thefollowingiscaused byhistaminereleasefromthe mast cells?
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I. Bronchodilation
II. Increasedbronchialglandsecretion v v v




III. Increased amountofmucus present intheairways v v v v v v v




a. Iand II only v c. IIIonly v v v




b. IIand IIIonly v d. I, II,III v v vv v v v




ANS: B v




Histamineisalsoapotentbronchoconstrictor.Inadditiontoitsbronchoconstrictiveactivity,histamine
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II)increasesbronchialglandsecretion,causingIII)anincreaseintheamount of mucus
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vpresent in the airways. Histamine mayalsohave an effect on vascular permeability similar to the
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effect of- SRS-A.
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PTS: 1 v v




7. Asympathomimeticdrugwould cause
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a. bronchodilation. c. Histaminerelease. v




b. bronchoconstriction. d. Vagusnervestimulation.
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ANS: A v




Asympathomimeticdrugwouldcausebronchodilation. Sympathomimeticagentsarethedrugsmost
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vcommonly used to reverse bronchospasm. v v v v




PTS: 1 v v




8. Stimulation ofthesympatheticnervoussystemcauses v v v v v v vv




a. vascularpermeability. c. bronchodilation. v




b. decreasedblood pressure. d. bronchoconstriction. v v v v




ANS: C v




Sympatheticnervoussystemstimulationcausesbronchodilation. v v v v v




PTS: 1 v v




9. Whichofthefollowingwould NOTcauseabronchospasmorbronchoconstriction?
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a. Leukotrienes c. Histamine
b. Beta1receptors d. Prostaglandins
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ANS: B v




Beta-1receptorswouldnotcauseabronchospasmorbronchoconstriction. Leukotrienes are
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oneof many chemical mediators released by the mast cells. Leukotrienes cause a direct, strong
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bronchoconstriction. Histamine is also apotent bronchoconstrictor. Prostaglandins cause a strong
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bronchospasm,especially in asthmatic patients.
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PTS: 1 v v