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NU 150 - Galen - Pharm Test 3-Study Guide with Complete Elaborated Answers.

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NSAIDs (actions) - Answer Actions: Does not belong to steroid group of drugs Inhibit prostaglandin synthesis by inhibiting an enzyme that triggers pain and inflammation. NSAIDs (Therapeutic class) - Answer Anti-inflammatory, Antipyretic, Analgesic NSAIDs (examples) - Answer ibuprofen (Motrin, Advil) indomethacin (Indocin) ketorolac (Toradol) naproxen (Naprosyn) piroxicam (Feldene) celecoxib (Celebrex) NSAIDs (uses) - Answer Mild to moderate pain Rheumatoid Arthritis Osteoarthritis Dysmenorrhea Morphine (uses) - Answer Prototype or "model" opioid Effective for moderately severe to severe pain Relief of severe cough (codeine) Pulmonary Edema (morphine) Obstetric Analgesia (nubain) Pre-operative to lessen anxiety and sedate Morphone (actions) - Answer Actions on organs: CNS: drowsiness, euphoria, sedation, mental clouding Eye: pupil constriction (pinpoint pupil) (miosis) Resp: depressed rate/depth of respirations and aggravation of asthma: suppress cough reflex (codeine) GIT = ↓peristalsis in stomach & intestines; gastric, ↓pancreas/bile secretions; gallbladder spasm (morphine) GUT = bladder contraction/spasm (urinary retention) Skin: itching and rash Morphone (adverse reactions) - Answer Adverse reactions: Physical dependence Possible withdrawal symptoms upon discontinuing. Opioid tolerance Need to address the patient's pain because it takes priority over concerns about drug addiction or physical dependence. Symptoms of opioid withdrawal - Answer Early signs

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NU 150 - Galen - Pharm Test 3-Study
Guide with Complete Elaborated
Answers.
NSAIDs (actions) - Answer Actions: Does not belong to steroid group of drugs Inhibit
prostaglandin synthesis by inhibiting an enzyme that triggers pain and inflammation.



NSAIDs (Therapeutic class) - Answer Anti-inflammatory, Antipyretic, Analgesic



NSAIDs (examples) - Answer ibuprofen (Motrin, Advil) indomethacin (Indocin) ketorolac
(Toradol) naproxen (Naprosyn) piroxicam (Feldene) celecoxib (Celebrex)



NSAIDs (uses) - Answer Mild to moderate pain Rheumatoid Arthritis Osteoarthritis
Dysmenorrhea



Morphine (uses) - Answer Prototype or "model" opioid

Effective for moderately severe to severe pain Relief of severe cough (codeine) Pulmonary
Edema (morphine) Obstetric Analgesia (nubain) Pre-operative to lessen anxiety and sedate



Morphone (actions) - Answer Actions on organs:

CNS: drowsiness, euphoria, sedation, mental clouding

Eye: pupil constriction (pinpoint pupil) (miosis)

Resp: depressed rate/depth of respirations and aggravation of asthma: suppress cough reflex
(codeine)

GIT = ↓peristalsis in stomach & intestines; gastric, ↓pancreas/bile secretions; gallbladder
spasm (morphine) GUT = bladder contraction/spasm (urinary retention)

Skin: itching and rash



Morphone (adverse reactions) - Answer Adverse reactions:

Physical dependence

Possible withdrawal symptoms upon discontinuing.

Opioid tolerance

Need to address the patient's pain because it takes priority over concerns about drug addiction
or physical dependence.



Symptoms of opioid withdrawal - Answer Early signs

Yawning, perspiring, tearing, nasal drainage

,Followed by:

Gooseflesh (goosebumps) • Abdominal cramps • Bone and muscle pain (rebound pain) • N/V,
diarrhea • Mydriasis (pupil dilation) • Intense craving for drug • Agitation • Elevated BP,
tachycardia • Seizures



Morphone (precautions) - Answer Use cautiously in individuals with head injury, morbid
obesity, and sleep apnea.

Precautions: Elderly: extreme confusion and hallucinations; smaller doses than younger adult
Undiagnosed abdominal pain Liver disease



Home use: Drug may cause drowsiness, dizziness • Caution with driving • Avoid alcohol • Take
med as directed • Explain how-to put-on patch



Patient education on PCA machine: - Answer Location of buttons • Regulation of dose and
time interval • Assure machine will not deliver dose until correct time • Pain relief should occur
shortly after pushing button • Inform nurse if pain not relieved after two doses



Naloxone (Narcan) (Use) - Answer Complete or partial reverse of opioid effects after surgery or
overdose



Naloxone (Narcan) (adverse reaction) - Answer n/v, tachycardia, hypertension, return of
postoperative pain, fever and dizziness



Hydrocodone (use) - Answer severe pain



Hydrocodone (adverse reaction) - Answer Sedation, sweating, headache, vertigo, lethargy,
confusion, lightheadedness, nausea, vomiting



Meperidine (Demerol) opioid (use) - Answer Acute moderate to severe pain, preoperative
sedation, anesthetic adjunct



Meperidine (Demerol) opioid (adverse reaction) - Answer Lightheadedness, constipation,
dizziness, N/V, respiratory depression



Anticholinergic (glycopyrrolate) cholinergic blocking drug (uses) - Answer Parasympathetic
drug (rest and digestion)

Oral: peptic ulcer

Parenteral: in conjunction with anesthesia to reduce bronchial and oral secretions, to block
cardiac vagal

, DRY "Can't see, pee, sh*t, spit" Hot as a Hare Dry as a Bone Blind as a Bat Red as a Beet Mad as
a Hatter

CV: increase heart rate Resp: dry mucus membranes; bronchial dilation

GIT: decrease GI motility, secretions and salivation

GUT-decrease bladder contraction, urinary retention

Eye: pupil dilation, increase in intraocular pressure



Anticholinergic (glycopyrrolate) cholinergic blocking drug (indications) - Answer Indications:

↓ muscle rigidity and diminishes tremors (Parkinson's)

inhibit the vagal stimulus (increase HR in bradycardia)

Bronchospasm (dilate bronchioles in asthma)

irritable bowel syndrome (relief of diarrhea S/S)

Urinary incontinence (relief of urgency in urination)

↓gastric & pancreatic secretions (acute pancreatitis)

↓ reduce respiratory secretions (pre-op)



Anticholinergic (glycopyrrolate) cholinergic blocking drug (teaching) - Answer Patient and
family teaching

Inform provider of adverse reactions

Photophobia = sunglasses, soft light

Dry mouth = frequent sips of water during the day; chew gum or dissolve hard candy

Constipation = drink plenty of fluids, increase fiber in diet

Heat prostration = fans, sponge bath



Acetaminophen (Tylenol) (antidote) - Answer Antidote : acetylcysteine



Acetaminophen (Tylenol) (uses) - Answer Mild to Moderate Pain

Reduce body temperature

Used when allergic to ASA

Used when on anticoagulant therapy

Recent minor surgical procedures



Acetaminophen (Tylenol) (adverse reactions) - Answer Adverse reactions

Few when taken as directed

Urticaria (hives)

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