MPJE Practice Questions and Answers with
Complete Solutions UPDATED!!!!!.
1. Controlled Substances
Which federal agency is primarily responsible for enforcing the Controlled Substances Act?
A. FDA
B. DEA
C. CDC
D. CMS
Answer: B — DEA
Rationale: The Drug Enforcement Administration (DEA) administers and enforces federal
controlled-substance laws under the Controlled Substances Act.
2. Schedule I
Which characteristic applies to Schedule I controlled substances?
A. Accepted medical use and low abuse potential
B. Accepted medical use with moderate abuse potential
C. No currently accepted medical use in the United States under federal law
D. Available without a prescription
Answer: C
Rationale: Schedule I substances are considered to have a high potential for abuse and no
currently accepted medical use under federal law, with a lack of accepted safety under medical
supervision.
3. Schedule II
,Which statement about Schedule II prescriptions is generally correct under federal law?
A. They may be refilled indefinitely
B. They cannot be refilled
C. They automatically expire after 7 days
D. They may only be prescribed by pharmacists
Answer: B — They cannot be refilled
Rationale: Federal law prohibits refills of Schedule II controlled-substance prescriptions. A new
prescription is generally required for additional quantities.
4. Schedule III–V Refills
A Schedule III controlled-substance prescription may generally be refilled:
A. Unlimited times for 5 years
B. Up to 5 times within 6 months
C. Once only
D. Only after DEA approval
Answer: B
Rationale: Under federal law, Schedule III and IV prescriptions may generally be refilled up to 5
times within 6 months from the date issued. Schedule V rules differ and may depend on the
drug and jurisdiction.
5. Schedule II Emergency Prescription
An emergency oral Schedule II prescription is generally limited to:
A. A 24-hour supply
B. The amount needed during the emergency period
C. A 30-day supply
D. An unlimited amount
Answer: B
,Rationale: Federal rules permit an emergency oral Schedule II prescription when specified
requirements are met. The quantity must be limited to what is required to treat the patient's
emergency condition.
6. DEA Form 222
DEA Form 222 is used primarily for:
A. Reporting medication errors
B. Ordering Schedule II controlled substances
C. Transferring prescriptions
D. Reporting adverse drug reactions
Answer: B
Rationale: DEA Form 222 is traditionally used for ordering Schedule II controlled substances,
although electronic ordering through CSOS is also authorized.
7. Controlled Substance Inventory
A pharmacy must perform a controlled-substance inventory:
A. Only when the DEA requests it
B. At least every 2 years
C. Every month
D. Every 10 years
Answer: B
Rationale: Federal law requires a complete inventory of controlled substances at least once
every 2 years.
8. DEA Registration
A pharmacy that dispenses controlled substances generally must:
A. Obtain a DEA registration
B. Obtain only an FDA registration
, C. Obtain only a state tax license
D. Obtain no registration
Answer: A
Rationale: Pharmacies that handle controlled substances generally need appropriate DEA
registration in addition to required state authorization.
9. Prescription Validity
A prescription should generally be dispensed only when:
A. It appears legitimate and is issued for a legitimate
medical purpose
B. The patient requests it
C. The drug is expensive
D. The patient offers identification
Answer: A
Rationale: Pharmacists have a responsibility to ensure prescriptions are issued for a legitimate
medical purpose and comply with applicable law.
10. Pharmacist Responsibility
Who has the professional responsibility to ensure a prescription is appropriately dispensed?
A. Cashier
B. Pharmacy technician alone
C. Pharmacist
D. Wholesaler
Answer: C — Pharmacist
Rationale: The pharmacist is responsible for the professional aspects of prescription dispensing,
subject to applicable state law and federal requirements.
Complete Solutions UPDATED!!!!!.
1. Controlled Substances
Which federal agency is primarily responsible for enforcing the Controlled Substances Act?
A. FDA
B. DEA
C. CDC
D. CMS
Answer: B — DEA
Rationale: The Drug Enforcement Administration (DEA) administers and enforces federal
controlled-substance laws under the Controlled Substances Act.
2. Schedule I
Which characteristic applies to Schedule I controlled substances?
A. Accepted medical use and low abuse potential
B. Accepted medical use with moderate abuse potential
C. No currently accepted medical use in the United States under federal law
D. Available without a prescription
Answer: C
Rationale: Schedule I substances are considered to have a high potential for abuse and no
currently accepted medical use under federal law, with a lack of accepted safety under medical
supervision.
3. Schedule II
,Which statement about Schedule II prescriptions is generally correct under federal law?
A. They may be refilled indefinitely
B. They cannot be refilled
C. They automatically expire after 7 days
D. They may only be prescribed by pharmacists
Answer: B — They cannot be refilled
Rationale: Federal law prohibits refills of Schedule II controlled-substance prescriptions. A new
prescription is generally required for additional quantities.
4. Schedule III–V Refills
A Schedule III controlled-substance prescription may generally be refilled:
A. Unlimited times for 5 years
B. Up to 5 times within 6 months
C. Once only
D. Only after DEA approval
Answer: B
Rationale: Under federal law, Schedule III and IV prescriptions may generally be refilled up to 5
times within 6 months from the date issued. Schedule V rules differ and may depend on the
drug and jurisdiction.
5. Schedule II Emergency Prescription
An emergency oral Schedule II prescription is generally limited to:
A. A 24-hour supply
B. The amount needed during the emergency period
C. A 30-day supply
D. An unlimited amount
Answer: B
,Rationale: Federal rules permit an emergency oral Schedule II prescription when specified
requirements are met. The quantity must be limited to what is required to treat the patient's
emergency condition.
6. DEA Form 222
DEA Form 222 is used primarily for:
A. Reporting medication errors
B. Ordering Schedule II controlled substances
C. Transferring prescriptions
D. Reporting adverse drug reactions
Answer: B
Rationale: DEA Form 222 is traditionally used for ordering Schedule II controlled substances,
although electronic ordering through CSOS is also authorized.
7. Controlled Substance Inventory
A pharmacy must perform a controlled-substance inventory:
A. Only when the DEA requests it
B. At least every 2 years
C. Every month
D. Every 10 years
Answer: B
Rationale: Federal law requires a complete inventory of controlled substances at least once
every 2 years.
8. DEA Registration
A pharmacy that dispenses controlled substances generally must:
A. Obtain a DEA registration
B. Obtain only an FDA registration
, C. Obtain only a state tax license
D. Obtain no registration
Answer: A
Rationale: Pharmacies that handle controlled substances generally need appropriate DEA
registration in addition to required state authorization.
9. Prescription Validity
A prescription should generally be dispensed only when:
A. It appears legitimate and is issued for a legitimate
medical purpose
B. The patient requests it
C. The drug is expensive
D. The patient offers identification
Answer: A
Rationale: Pharmacists have a responsibility to ensure prescriptions are issued for a legitimate
medical purpose and comply with applicable law.
10. Pharmacist Responsibility
Who has the professional responsibility to ensure a prescription is appropriately dispensed?
A. Cashier
B. Pharmacy technician alone
C. Pharmacist
D. Wholesaler
Answer: C — Pharmacist
Rationale: The pharmacist is responsible for the professional aspects of prescription dispensing,
subject to applicable state law and federal requirements.
