COMPREHENSIVE ANCC FAMILY
NURSE PRACTITIONER PRACTICE
EXAM QUESTIONS AND ANSWERS
1. A 68-year-old male presents with a new onset of a ‘harsh’ systolic crescendo-decrescendo
murmur heard best at the second intercostal space, right sternal border, radiating to the
carotids. Which of the following is the most likely diagnosis?
A. Mitral Valve Prolapse
B. Aortic Regurgitation
C. Aortic Stenosis
D. Mitral Regurgitation
Answer: C
Conceptual Explanation: Aortic stenosis typically presents as a harsh systolic murmur at
the right upper sternal border that radiates to the neck. Mitral regurgitation is holosystolic
and radiates to the axilla.
,2. When conducting a study to determine the effectiveness of a new hypertension
medication, the researcher fails to reject the null hypothesis when it is actually false. This is
known as:
A. Type I Error
B. Selection Bias
C. Confounding Variable
D. Type II Error
Answer: D
Conceptual Explanation: Type II error (false negative) occurs when the researcher fails to
reject a null hypothesis that is actually false. Type I error is rejecting a true null hypothesis.
3. A 45-year-old female patient with a history of hypertension is prescribed Lisinopril. She
presents today with a dry, non-productive cough. Which mechanism explains this side effect?
A. Peripheral Vasodilation
B. Inhibition of Angiotensin II receptors
C. Increased levels of Aldosterone
D. Accumulation of Bradykinin
Answer: D
Conceptual Explanation: ACE inhibitors prevent the breakdown of bradykinin, which
accumulates in the lungs and causes a dry cough in some patients.
, 4. Which of the following Medicare parts covers outpatient diagnostic tests and provider
visits?
A. Part A
B. Part D
C. Part C
D. Part B
Answer: D
Conceptual Explanation: Medicare Part B covers medically necessary services like doctor
visits and outpatient care. Part A covers hospital insurance.
5. A 24-year-old male presents with painful, shallow vesicles on an erythematous base in the
genital area. Which diagnostic test is most sensitive for confirming Herpes Simplex Virus?
A. Tzanck Smear
B. Gram Stain
C. RPR Test
D. HSV PCR
Answer: D
Conceptual Explanation: Polymerase Chain Reaction (PCR) is the most sensitive and
preferred test for detecting HSV DNA from lesions compared to the older Tzanck smear.
NURSE PRACTITIONER PRACTICE
EXAM QUESTIONS AND ANSWERS
1. A 68-year-old male presents with a new onset of a ‘harsh’ systolic crescendo-decrescendo
murmur heard best at the second intercostal space, right sternal border, radiating to the
carotids. Which of the following is the most likely diagnosis?
A. Mitral Valve Prolapse
B. Aortic Regurgitation
C. Aortic Stenosis
D. Mitral Regurgitation
Answer: C
Conceptual Explanation: Aortic stenosis typically presents as a harsh systolic murmur at
the right upper sternal border that radiates to the neck. Mitral regurgitation is holosystolic
and radiates to the axilla.
,2. When conducting a study to determine the effectiveness of a new hypertension
medication, the researcher fails to reject the null hypothesis when it is actually false. This is
known as:
A. Type I Error
B. Selection Bias
C. Confounding Variable
D. Type II Error
Answer: D
Conceptual Explanation: Type II error (false negative) occurs when the researcher fails to
reject a null hypothesis that is actually false. Type I error is rejecting a true null hypothesis.
3. A 45-year-old female patient with a history of hypertension is prescribed Lisinopril. She
presents today with a dry, non-productive cough. Which mechanism explains this side effect?
A. Peripheral Vasodilation
B. Inhibition of Angiotensin II receptors
C. Increased levels of Aldosterone
D. Accumulation of Bradykinin
Answer: D
Conceptual Explanation: ACE inhibitors prevent the breakdown of bradykinin, which
accumulates in the lungs and causes a dry cough in some patients.
, 4. Which of the following Medicare parts covers outpatient diagnostic tests and provider
visits?
A. Part A
B. Part D
C. Part C
D. Part B
Answer: D
Conceptual Explanation: Medicare Part B covers medically necessary services like doctor
visits and outpatient care. Part A covers hospital insurance.
5. A 24-year-old male presents with painful, shallow vesicles on an erythematous base in the
genital area. Which diagnostic test is most sensitive for confirming Herpes Simplex Virus?
A. Tzanck Smear
B. Gram Stain
C. RPR Test
D. HSV PCR
Answer: D
Conceptual Explanation: Polymerase Chain Reaction (PCR) is the most sensitive and
preferred test for detecting HSV DNA from lesions compared to the older Tzanck smear.
