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PRACTICE TEST
,1. A 24-year-old man presents with severe pain in the right lower quadrant that began around
the umbilicus and later migrated. Which nerve pathway most directly explains the ini al poorly
localized pain?
A. Greater splanchnic nerve
B. Visceral afferent fibers traveling with sympathe c nerves
C. Phrenic nerve
D. Pudendal nerve
Answer: B. Visceral afferent fibers traveling with sympathe c nerves
Ra onale: Visceral pain from the appendix ini ally travels with sympathe c afferent fibers and
enters the spinal cord around T10, producing poorly localized periumbilical pain. As
inflamma on reaches the parietal peritoneum, pain becomes localized to the right lower
quadrant.
2. A pa ent develops weakness of the right side of the face involving both the forehead and
lower face. Which cranial nerve is most likely affected?
A. CN V
B. CN VII
C. CN IX
D. CN XII
Answer: B. CN VII
Ra onale: A peripheral facial nerve lesion causes ipsilateral weakness of both the upper and
lower facial muscles. A supranuclear cor cobulbar lesion typically spares the forehead because
of bilateral cor cal innerva on.
3. Which immunoglobulin is primarily responsible for immediate hypersensi vity reac ons?
A. IgA
B. IgG
C. IgM
D. IgE
Answer: D. IgE
Ra onale: IgE binds Fc receptors on mast cells and basophils. Cross-linking of IgE by an allergen
triggers degranula on and release of histamine and other inflammatory mediators.
, 4. A pa ent with type 1 diabetes mellitus develops metabolic acidosis. Which laboratory finding
is most characteris c of diabe c ketoacidosis?
A. Decreased anion gap
B. Increased bicarbonate
C. Increased serum ketones
D. Respiratory acidosis
Answer: C. Increased serum ketones
Ra onale: Insulin deficiency promotes lipolysis and hepa c ketogenesis, resul ng in elevated β-
hydroxybutyrate and acetoacetate and producing a high-anion-gap metabolic acidosis.
5. A drug is eliminated according to first-order kine cs. Which statement best describes this
process?
A. A constant amount is eliminated per unit me
B. A constant percentage is eliminated per unit me
C. Elimina on is independent of drug concentra on
D. Elimina on occurs only through the kidneys
Answer: B. A constant percentage is eliminated per unit me
Ra onale: First-order elimina on means the rate of drug elimina on is propor onal to plasma
concentra on. Therefore, a constant frac on or percentage of the drug is removed per unit me.
6. Which organism is classically associated with a urease-posi ve urinary tract infec on and
alkaline urine?
A. Escherichia coli
B. Proteus mirabilis
C. Enterococcus faecalis
D. Klebsiella pneumoniae
Answer: B. Proteus mirabilis
Ra onale: Proteus species produce urease, which converts urea into ammonia. The resul ng
alkaline urine promotes forma on of struvite stones composed of magnesium ammonium
phosphate.