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Physician Licensure Exam (PLE) 2026 Complete Q-Bank: 500+ High-Yield Practice Questions with Correct Answers & Detailed Rationales for Board Exam Success – Author: Medical Exam Prep Experts

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Ace your medical board exams on the very first attempt with this ultimate, all-in-one question bank featuring over 500+ meticulously curated practice questions, 100% correct answers, and comprehensive detailed rationales covering the entire scope of the Physician Licensure Exam (PLE). This comprehensive review guide is expertly organized by core clinical subjects, including Internal Medicine, Pediatrics, Obstetrics & Gynecology, Surgery, Legal Medicine & Medical Jurisprudence, and Preventive Medicine & Public Health. Authored by experienced medical educators, this resource delves deep into high-yield, exam-tested topics such as acute coronary syndrome management, diabetes mellitus pharmacotherapy, rheumatoid arthritis and SLE diagnostic criteria, pediatric infectious diseases and immunizations, obstetric emergencies and prenatal screening, surgical oncology and trauma management, medico-legal principles, and public health epidemiology and biostatistics. Unlike standard textbooks, this question bank is designed in an easy-to-digest Q&A format, with every correct answer clearly identified and supported by precise explanations and references from trusted sources like Harrison's Principles of Internal Medicine, Nelson Textbook of Pediatrics, and Schwartz's Principles of Surgery. Whether you are a graduating medical student preparing for the PLE, an international medical graduate seeking licensure, or a resident reviewing for in-service exams, this resource provides the rigorous practice, clinical confidence, and exam-day strategy you need to achieve a top score and launch your medical career. Save hours of study time, eliminate test anxiety, and walk into your exam fully prepared with this indispensable, high-yield study companion.

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physician
licensure exam

,TABLE OF CONTENTS

Internal Medicine................................................................................. 3

Pediatrics ............................................................................................ 42

Obstetrics & Gynecology ................................................................. 82

Surgery ............................................................................................. 117

Legal Medicine & Medical Jurisprudence ...................................152

Preventive Medicine ....................................................................... 182

,INTERNAL MEDICINE

, QUESTION ANSWER EXPLANATION

1. An 80-year-old man presents to the D D. Exacerbated by position changes.
OPD complaining of heavy and
squeezing chest pain with radiation to Chest pain caused by myocardial ischemia
the right arm. It is sometimes can be characterized as
exacerbated by changes in position. ● Aching
● Heavy
ECG was done which revealed ST ● Squeezing
elevation in leads V1-V2. Which of ● Crushing or constricting
these symptoms is NOT consistent with
the most likely diagnosis? The location is retrosternal. Radiation usually
occurs to the ulnar surface of the left arm,
A. Squeezing chest pain neck, jaw, shoulders, and even the right
B. Radiation to the right arm arm.
C. Chest pain described as
heaviness Chest pain exacerbated by changes in
D. Exacerbated by position position is usually associated with pleuritic
changes pain of pericarditis.

Reference:
Loscalzo J, & Fauci A, & Kasper D, & Hauser S, &
Longo D, & Jameson J. (2022). Chapter 14: Chest
discomfort. In D.A. Marrow (Ed.), Harrison's Principles
of Internal Medicine (21st ed., Vol.1, pp. 601-603). New
York, NY: McGraw Hill.

2. An 80-year-old man presents to the C C. NSTEMI
OPD complaining of heavy and
squeezing chest pain with radiation to To diagnose NSTEMI, the following has to be
the right arm. present:
BP was taken which showed: 70/50 1. Characteristic ischemic chest pain
mmHg 2. ECG with NO ST elevations (e.g., ST
depression)
ECG was done which revealed 3. Troponin I elevation
ST-segment depression in leads V1-V2.
Troponin I was positive. All these 3 are present in this patient with
NSTEMI.
What is the most appropriate
diagnosis? STEMI is diagnosed if the ECG showed ST
elevation.
A. Chronic coronary syndrome
B. Unstable angina Unstable angina would show no elevation of
C. NSTEMI Troponin I.
D. STEMI
Reference:
Loscalzo J, & Fauci A, & Kasper D, & Hauser S, &
Longo D, & Jameson J. (2022). Non-ST-segment
elevation acute coronary syndrome: Non-ST segment
elevation, myocardial infarction, and unstable angina.
In R.P. Giugliano, C.P. Cannon, & E. Braunwald (Eds.),
Harrison's Principles of Internal Medicine (21st ed.,
Vol.1, p. 8758). New York, NY: McGraw Hill.

3. An 80-year-old man with diabetes A A. Refer to Cardio for invasive strategy
and hypertension presents to the OPD
complaining of heavy and squeezing In NSTEMI patients classified as high-risk,

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