NBME CBSE EXAM SCRIPT VERIFIED
QUESTIONS WITH ACCURATE ANSWERS
●● Gaucher's cells in *Gaucher's Dz* (lysosomal storage Dz);
macrophage looks like crumpled tissue paper
Answer: histo of macrophage
●● foam cells (stored w/ fat) in *niemann pick Dz*
Answer: histo of macrophage 2
●● senile plaque in Alzheimer's Dz
Answer: β-amyloid protein
●● *MS*
-areas of oligodendrocyte loss + reactive gliosis
Answer: paraventricular plaques
●● butterfly glioma in *Glioblastoma multiforme*
Answer: tumor crossing corpus callosum
●● plasmodium/malaria
,Tx: chloroquine/Mefloquine
Answer: blood smear. Tx?
●● candida (know this img)
Answer: ID the opportunistic mycoses
●● looks like a stoma (mouth)
think gingivostomatitis -> 1º HSV infxn
Answer: ID this smear
●● jk what cutaneous lesion?
borrelia (lyme Dz - Pt was fkn round in the woods); usu Cx lesion is
erythema migrans = target sign w/ zone of central clearing but that's
actually rarely seen so rmr this
Answer: ID whose ass this is
●● double refractive walls w/ broad based budding so think Blasto
(focus on L pic); in great lakes, ohio, miss river
Answer: iD this fungi in lungs
,●● notice how fungi is HIDING in macrophage, so Histoplasma
Answer: id this fungus in i-c Pt. (BM)
●● (arrow points to intranuc inclusion so u know its virus): CMV
Answer: interstitial PNA in transplant Pt.
●● ecythemic gangrenosum d/t Pseudomonas
Answer: necrotic patches in skin in cancer Pt. d/t
●● spherules containing endospores (coccidio)
Answer: fungal
●● notice acute angles ("V"): aspergillus fumigatus
Answer: fungal2
●● india ink stain: crypto/HIV Pt. with meningitis
Answer: ID Cx stain/bug/Pt/Dx
●● tear drop w/ owl-like face
GIARDIA
Answer: recurrent diarrhea d/t protozoan
, ●● granuloma (Tb)
-IFN-y
Answer: the hell is you lookin at; also what cell responsible for this?
●● 2 Ig monomers:
J in middle = J chain; SC = secretory component
secretory *IgA*: found in colostrum (also tears, saliva, mucus)
Answer: name the Ig; primarily found in
●● atypical lymphocytes (activated CD8 T cells);
seen in infectious mono (d/t CMV or EBV)
Answer: what are these?
Dx?
●● myeloblasts w/ coarse rod-shaped intra-cytoplasmic granules aka
*auer rods*; think *AML*
Answer: seen in blood smear
●● neurofibromas, so think NFT1
Answer: cuatenous lesions are?
QUESTIONS WITH ACCURATE ANSWERS
●● Gaucher's cells in *Gaucher's Dz* (lysosomal storage Dz);
macrophage looks like crumpled tissue paper
Answer: histo of macrophage
●● foam cells (stored w/ fat) in *niemann pick Dz*
Answer: histo of macrophage 2
●● senile plaque in Alzheimer's Dz
Answer: β-amyloid protein
●● *MS*
-areas of oligodendrocyte loss + reactive gliosis
Answer: paraventricular plaques
●● butterfly glioma in *Glioblastoma multiforme*
Answer: tumor crossing corpus callosum
●● plasmodium/malaria
,Tx: chloroquine/Mefloquine
Answer: blood smear. Tx?
●● candida (know this img)
Answer: ID the opportunistic mycoses
●● looks like a stoma (mouth)
think gingivostomatitis -> 1º HSV infxn
Answer: ID this smear
●● jk what cutaneous lesion?
borrelia (lyme Dz - Pt was fkn round in the woods); usu Cx lesion is
erythema migrans = target sign w/ zone of central clearing but that's
actually rarely seen so rmr this
Answer: ID whose ass this is
●● double refractive walls w/ broad based budding so think Blasto
(focus on L pic); in great lakes, ohio, miss river
Answer: iD this fungi in lungs
,●● notice how fungi is HIDING in macrophage, so Histoplasma
Answer: id this fungus in i-c Pt. (BM)
●● (arrow points to intranuc inclusion so u know its virus): CMV
Answer: interstitial PNA in transplant Pt.
●● ecythemic gangrenosum d/t Pseudomonas
Answer: necrotic patches in skin in cancer Pt. d/t
●● spherules containing endospores (coccidio)
Answer: fungal
●● notice acute angles ("V"): aspergillus fumigatus
Answer: fungal2
●● india ink stain: crypto/HIV Pt. with meningitis
Answer: ID Cx stain/bug/Pt/Dx
●● tear drop w/ owl-like face
GIARDIA
Answer: recurrent diarrhea d/t protozoan
, ●● granuloma (Tb)
-IFN-y
Answer: the hell is you lookin at; also what cell responsible for this?
●● 2 Ig monomers:
J in middle = J chain; SC = secretory component
secretory *IgA*: found in colostrum (also tears, saliva, mucus)
Answer: name the Ig; primarily found in
●● atypical lymphocytes (activated CD8 T cells);
seen in infectious mono (d/t CMV or EBV)
Answer: what are these?
Dx?
●● myeloblasts w/ coarse rod-shaped intra-cytoplasmic granules aka
*auer rods*; think *AML*
Answer: seen in blood smear
●● neurofibromas, so think NFT1
Answer: cuatenous lesions are?
