NURS 663 EXAMS EVALUATION ANSWERS AND
QUESTIONS SET A+
✔✔escitalopram dosing - ✔✔Initial dose is 10 mg per day increase at 10 mg a day per
week and the max dose is 30 mg a day
✔✔Fluoxetine mnemonic - ✔✔FLUoxetine remember that the flu lasts 1 to 2 weeks
which is related to the longer half-life of fluoxetine
✔✔Fluoxetine interactions - ✔✔-Warfarin (flux can displace it)
-St. John's wort (may cause Serotonin Syndrome) burn up and can overdose
-Dabigatran
P450 interactions are significant
✔✔Sertraline mnemonic - ✔✔SQUIRTraline related to its adverse effects of increased
diarrhea and the benefit of a safe while pregnancy and breast-feeding
✔✔sertraline indication/benefits - ✔✔MDD, OCD, PMDD middle of the road
antidepressant with no buildup
✔✔Paroxetine adverse effects - ✔✔Withdrawal symptoms, more sedating, increase
appetite
✔✔Paroxetine mnemonic - ✔✔Think pair of oxen related to it works fast and has a short
half-life
✔✔Paroxetine Interactions - ✔✔Potent CYP 2D6 Inhibitor and substrate equals many
interactions
✔✔Paroxetine dosing - ✔✔Immediate release start at 20 mg per day and titrate 10 to 20
mg per day per week max dose is 50 mg per day, Extended release start at 25 mg per
day increase by 12.5 mg per day each week to a max dose of 62.5 mg
, ✔✔Anti-depressants side effects 10 - ✔✔Anhedonia, apathy, n/v, drowsy/dizzy,
somnolence, headache, bruxism, vivid dreams, fatigue, change in sexual behavior.
✔✔Antidepressant Mechanism on action - ✔✔Ser-438 residue determines potency
(hSERT) SSRI (unk exact mech).
✔✔sertraline dose - ✔✔Init 20mg/day, titrate 25-50mg/day every 1-2wk, max dose
200mg
✔✔Fluoxetine indications - ✔✔Depression, d/c syndrome (give 20mg tab), for
activation, noncompliance, and to decrease appetite
✔✔Citalopram (Celexa) and Escitalopram (Lexapro) Pneumonic - ✔✔Think car seat for
SEATalopram to remember to obtain an Electrocardiogram forQTC prolongation
✔✔Carbamazepine treats - ✔✔First line and acute mania, acute/prophylaxis mania,
anti-aggressive, rapid cycling, mix patience
✔✔Carbamazepine labs - ✔✔Level range is 4-12, LFTs, CBC, EKG, multiple drug to
drug interactions
✔✔Carbamazepine dosing - ✔✔100 milligrams a day initially then increase 200 mg per
day everyone to four days to a max dose of 1.6 g per day
✔✔Carbamazepine mnemonic - ✔✔CBZ Cranial nerve pain, bipolar disorder, seiZures.
CarbamASIApine Do you remember that Asian dissent patients have an increased risk
of Steven Johnson syndrome and are recommended to be screened
✔✔Carbamazepine side effects - ✔✔Water retention, ataxia, n/v/d, rash, dizzy,
sedation, confusion, transaminitis
✔✔Carbamazepine adverse effects - ✔✔CNS, rash. Rarely SJS/toxic epidermal
necrolysis. Black box warning for aplastic anemia, thrombocytopenia, leukopenia.
✔✔Carbamazepine mechanism - ✔✔Block voltage-dependent sodium channels,
anticholinergic, antidiuretic, antimania, anticonvulsant, antineuralgic, antiarrythmic
✔✔Valproic Acid (Depakote) mnemonic - ✔✔ValproATE a folate PLaTe, folate linked to
neural tube defects. Pancreatitis, Liver problems (hepatotoxic), Thrombocytopenia
✔✔Valproate (Depakote) indications - ✔✔Mania (equal to Li), comorbid sub.
Abuse/anxious, mixed patient, rapid cycling
QUESTIONS SET A+
✔✔escitalopram dosing - ✔✔Initial dose is 10 mg per day increase at 10 mg a day per
week and the max dose is 30 mg a day
✔✔Fluoxetine mnemonic - ✔✔FLUoxetine remember that the flu lasts 1 to 2 weeks
which is related to the longer half-life of fluoxetine
✔✔Fluoxetine interactions - ✔✔-Warfarin (flux can displace it)
-St. John's wort (may cause Serotonin Syndrome) burn up and can overdose
-Dabigatran
P450 interactions are significant
✔✔Sertraline mnemonic - ✔✔SQUIRTraline related to its adverse effects of increased
diarrhea and the benefit of a safe while pregnancy and breast-feeding
✔✔sertraline indication/benefits - ✔✔MDD, OCD, PMDD middle of the road
antidepressant with no buildup
✔✔Paroxetine adverse effects - ✔✔Withdrawal symptoms, more sedating, increase
appetite
✔✔Paroxetine mnemonic - ✔✔Think pair of oxen related to it works fast and has a short
half-life
✔✔Paroxetine Interactions - ✔✔Potent CYP 2D6 Inhibitor and substrate equals many
interactions
✔✔Paroxetine dosing - ✔✔Immediate release start at 20 mg per day and titrate 10 to 20
mg per day per week max dose is 50 mg per day, Extended release start at 25 mg per
day increase by 12.5 mg per day each week to a max dose of 62.5 mg
, ✔✔Anti-depressants side effects 10 - ✔✔Anhedonia, apathy, n/v, drowsy/dizzy,
somnolence, headache, bruxism, vivid dreams, fatigue, change in sexual behavior.
✔✔Antidepressant Mechanism on action - ✔✔Ser-438 residue determines potency
(hSERT) SSRI (unk exact mech).
✔✔sertraline dose - ✔✔Init 20mg/day, titrate 25-50mg/day every 1-2wk, max dose
200mg
✔✔Fluoxetine indications - ✔✔Depression, d/c syndrome (give 20mg tab), for
activation, noncompliance, and to decrease appetite
✔✔Citalopram (Celexa) and Escitalopram (Lexapro) Pneumonic - ✔✔Think car seat for
SEATalopram to remember to obtain an Electrocardiogram forQTC prolongation
✔✔Carbamazepine treats - ✔✔First line and acute mania, acute/prophylaxis mania,
anti-aggressive, rapid cycling, mix patience
✔✔Carbamazepine labs - ✔✔Level range is 4-12, LFTs, CBC, EKG, multiple drug to
drug interactions
✔✔Carbamazepine dosing - ✔✔100 milligrams a day initially then increase 200 mg per
day everyone to four days to a max dose of 1.6 g per day
✔✔Carbamazepine mnemonic - ✔✔CBZ Cranial nerve pain, bipolar disorder, seiZures.
CarbamASIApine Do you remember that Asian dissent patients have an increased risk
of Steven Johnson syndrome and are recommended to be screened
✔✔Carbamazepine side effects - ✔✔Water retention, ataxia, n/v/d, rash, dizzy,
sedation, confusion, transaminitis
✔✔Carbamazepine adverse effects - ✔✔CNS, rash. Rarely SJS/toxic epidermal
necrolysis. Black box warning for aplastic anemia, thrombocytopenia, leukopenia.
✔✔Carbamazepine mechanism - ✔✔Block voltage-dependent sodium channels,
anticholinergic, antidiuretic, antimania, anticonvulsant, antineuralgic, antiarrythmic
✔✔Valproic Acid (Depakote) mnemonic - ✔✔ValproATE a folate PLaTe, folate linked to
neural tube defects. Pancreatitis, Liver problems (hepatotoxic), Thrombocytopenia
✔✔Valproate (Depakote) indications - ✔✔Mania (equal to Li), comorbid sub.
Abuse/anxious, mixed patient, rapid cycling
