NU 310 EXAM 2 ACTUAL EXAM NEWEST 2026-2027
WITH COMPLETE QUESTIONS AND CORRECT
DETAILED ANSWERS BRAND NEW VERSION!
140 QUESTIONS
TABLE OF CONTENTS
# TOPIC
1 Apply advanced pathophysiology to clinical scenarios
2 Interpret diagnostic data and adjust nursing interventions
3 Evaluate ethical and legal implications in nursing practice
4 Synthesize pharmacological principles with patient safety
5 Nu 310 Exam 2 Actual Exam Newest 2026
6 2027 With Complete Questions And Correct Detailed Answers Brand New Version!
7 Foundations of Nursing - Medical-Surgical and Advanced Concepts
8 Applied Nursing - Medical-Surgical and Advanced Concepts
9 Advanced Nursing - Medical-Surgical and Advanced Concepts
10 Nursing - Medical-Surgical and Advanced Concepts Review
Q1 APPLY ADVANCED PATHOPHYSIOLOGY TO CLINICAL SCENARIOS
A patient with chronic heart failure is started on sacubitril/valsartan. Which finding
indicates the need to discontinue this medication?
A. Serum creatinine increase of 0.3 mg/dL
B. Symptomatic hypotension
C. Serum potassium of 5.2 mEq/L
D. History of angioedema CORRECT
RATIONALE: Sacubitril/valsartan is contraindicated in patients with a history of angioedema due
to the risk of recurrence. While hypotension, hyperkalemia, and creatinine elevation require
monitoring, they are manageable and not absolute contraindications.
Page 1
,Q2 APPLY ADVANCED PATHOPHYSIOLOGY TO CLINICAL SCENARIOS
Which acid-base disturbance is most likely in a patient with prolonged vomiting
and subsequent hypokalemia?
A. Respiratory alkalosis with compensatory renal bicarbonate excretion
B. Metabolic acidosis with increased anion gap
C. Metabolic alkalosis with paradoxical aciduria CORRECT
D. Respiratory acidosis with renal bicarbonate retention
RATIONALE: Prolonged vomiting causes loss of hydrogen and chloride ions, leading to metabolic
alkalosis. Hypokalemia results from renal potassium loss as the kidneys attempt to conserve
hydrogen ions, causing paradoxical aciduria. This is a classic pathophysiologic response.
Q3 APPLY ADVANCED PATHOPHYSIOLOGY TO CLINICAL SCENARIOS
In a patient with sepsis, which hemodynamic profile is consistent with the
hyperdynamic phase?
A. Low cardiac output, high systemic vascular resistance
B. High cardiac output, low systemic vascular resistance CORRECT
C. Low cardiac output, low pulmonary capillary wedge pressure
D. High cardiac output, high central venous pressure
RATIONALE: In the hyperdynamic phase of sepsis, systemic vasodilation reduces systemic
vascular resistance, while cardiac output increases as a compensatory mechanism. This results
in warm extremities, bounding pulses, and wide pulse pressure. Low SVR and high CO are
hallmark findings.
Page 2
,Q4 APPLY ADVANCED PATHOPHYSIOLOGY TO CLINICAL SCENARIOS
A nurse is preparing to administer a blood transfusion. Which action is most
important to prevent a transfusion-associated circulatory overload (TACO)?
A. Verify the patient's blood type and crossmatch
B. Administer a diuretic before transfusion
C. Slow the infusion rate and monitor for dyspnea CORRECT
D. Use a leukocyte-reduced blood product
RATIONALE: TACO is caused by rapid infusion of blood products, especially in patients with
heart failure or renal impairment. Slowing the infusion rate and monitoring for signs of fluid
overload (dyspnea, crackles, hypertension) are essential. Diuretics may be used but are not the
primary preventive measure.
Q5 APPLY ADVANCED PATHOPHYSIOLOGY TO CLINICAL SCENARIOS
Which finding is most indicative of malignant hyperthermia in a postoperative
patient?
A. Temperature of 38.5°C and tachycardia
B. Muscle rigidity and elevated creatine kinase CORRECT
C. Hypotension and bradycardia
D. Respiratory depression and hypoxia
RATIONALE: Malignant hyperthermia is a hypermetabolic crisis triggered by volatile anesthetics
or succinylcholine. Muscle rigidity, especially of the jaw, and elevated creatine kinase are classic
signs. While hyperthermia and tachycardia occur, rigidity and CK elevation are more specific.
Page 3
, Q6 APPLY ADVANCED PATHOPHYSIOLOGY TO CLINICAL SCENARIOS
A patient on vancomycin develops red man syndrome. Which action is
appropriate?
A. Stop the infusion and administer diphenhydramine CORRECT
B. Slow the infusion rate and give epinephrine
C. Discontinue vancomycin and switch to linezolid
D. Continue the infusion and monitor closely
RATIONALE: Red man syndrome is an infusion-related reaction caused by histamine release,
not a true allergy. Management includes slowing or stopping the infusion and administering
antihistamines like diphenhydramine. Epinephrine is reserved for anaphylaxis, and
discontinuation is not always necessary.
Q7 APPLY ADVANCED PATHOPHYSIOLOGY TO CLINICAL SCENARIOS
Which ethical principle is most directly violated when a nurse discloses a patient's
HIV status to a family member without consent?
A. Beneficence
B. Justice
C. Autonomy CORRECT
D. Nonmaleficence
RATIONALE: Autonomy respects the patient's right to decide who receives their health
information. Unauthorized disclosure violates this principle. While nonmaleficence and
beneficence are important, the primary violation is against autonomy, as it disregards the
patient's control over personal data.
Page 4
WITH COMPLETE QUESTIONS AND CORRECT
DETAILED ANSWERS BRAND NEW VERSION!
140 QUESTIONS
TABLE OF CONTENTS
# TOPIC
1 Apply advanced pathophysiology to clinical scenarios
2 Interpret diagnostic data and adjust nursing interventions
3 Evaluate ethical and legal implications in nursing practice
4 Synthesize pharmacological principles with patient safety
5 Nu 310 Exam 2 Actual Exam Newest 2026
6 2027 With Complete Questions And Correct Detailed Answers Brand New Version!
7 Foundations of Nursing - Medical-Surgical and Advanced Concepts
8 Applied Nursing - Medical-Surgical and Advanced Concepts
9 Advanced Nursing - Medical-Surgical and Advanced Concepts
10 Nursing - Medical-Surgical and Advanced Concepts Review
Q1 APPLY ADVANCED PATHOPHYSIOLOGY TO CLINICAL SCENARIOS
A patient with chronic heart failure is started on sacubitril/valsartan. Which finding
indicates the need to discontinue this medication?
A. Serum creatinine increase of 0.3 mg/dL
B. Symptomatic hypotension
C. Serum potassium of 5.2 mEq/L
D. History of angioedema CORRECT
RATIONALE: Sacubitril/valsartan is contraindicated in patients with a history of angioedema due
to the risk of recurrence. While hypotension, hyperkalemia, and creatinine elevation require
monitoring, they are manageable and not absolute contraindications.
Page 1
,Q2 APPLY ADVANCED PATHOPHYSIOLOGY TO CLINICAL SCENARIOS
Which acid-base disturbance is most likely in a patient with prolonged vomiting
and subsequent hypokalemia?
A. Respiratory alkalosis with compensatory renal bicarbonate excretion
B. Metabolic acidosis with increased anion gap
C. Metabolic alkalosis with paradoxical aciduria CORRECT
D. Respiratory acidosis with renal bicarbonate retention
RATIONALE: Prolonged vomiting causes loss of hydrogen and chloride ions, leading to metabolic
alkalosis. Hypokalemia results from renal potassium loss as the kidneys attempt to conserve
hydrogen ions, causing paradoxical aciduria. This is a classic pathophysiologic response.
Q3 APPLY ADVANCED PATHOPHYSIOLOGY TO CLINICAL SCENARIOS
In a patient with sepsis, which hemodynamic profile is consistent with the
hyperdynamic phase?
A. Low cardiac output, high systemic vascular resistance
B. High cardiac output, low systemic vascular resistance CORRECT
C. Low cardiac output, low pulmonary capillary wedge pressure
D. High cardiac output, high central venous pressure
RATIONALE: In the hyperdynamic phase of sepsis, systemic vasodilation reduces systemic
vascular resistance, while cardiac output increases as a compensatory mechanism. This results
in warm extremities, bounding pulses, and wide pulse pressure. Low SVR and high CO are
hallmark findings.
Page 2
,Q4 APPLY ADVANCED PATHOPHYSIOLOGY TO CLINICAL SCENARIOS
A nurse is preparing to administer a blood transfusion. Which action is most
important to prevent a transfusion-associated circulatory overload (TACO)?
A. Verify the patient's blood type and crossmatch
B. Administer a diuretic before transfusion
C. Slow the infusion rate and monitor for dyspnea CORRECT
D. Use a leukocyte-reduced blood product
RATIONALE: TACO is caused by rapid infusion of blood products, especially in patients with
heart failure or renal impairment. Slowing the infusion rate and monitoring for signs of fluid
overload (dyspnea, crackles, hypertension) are essential. Diuretics may be used but are not the
primary preventive measure.
Q5 APPLY ADVANCED PATHOPHYSIOLOGY TO CLINICAL SCENARIOS
Which finding is most indicative of malignant hyperthermia in a postoperative
patient?
A. Temperature of 38.5°C and tachycardia
B. Muscle rigidity and elevated creatine kinase CORRECT
C. Hypotension and bradycardia
D. Respiratory depression and hypoxia
RATIONALE: Malignant hyperthermia is a hypermetabolic crisis triggered by volatile anesthetics
or succinylcholine. Muscle rigidity, especially of the jaw, and elevated creatine kinase are classic
signs. While hyperthermia and tachycardia occur, rigidity and CK elevation are more specific.
Page 3
, Q6 APPLY ADVANCED PATHOPHYSIOLOGY TO CLINICAL SCENARIOS
A patient on vancomycin develops red man syndrome. Which action is
appropriate?
A. Stop the infusion and administer diphenhydramine CORRECT
B. Slow the infusion rate and give epinephrine
C. Discontinue vancomycin and switch to linezolid
D. Continue the infusion and monitor closely
RATIONALE: Red man syndrome is an infusion-related reaction caused by histamine release,
not a true allergy. Management includes slowing or stopping the infusion and administering
antihistamines like diphenhydramine. Epinephrine is reserved for anaphylaxis, and
discontinuation is not always necessary.
Q7 APPLY ADVANCED PATHOPHYSIOLOGY TO CLINICAL SCENARIOS
Which ethical principle is most directly violated when a nurse discloses a patient's
HIV status to a family member without consent?
A. Beneficence
B. Justice
C. Autonomy CORRECT
D. Nonmaleficence
RATIONALE: Autonomy respects the patient's right to decide who receives their health
information. Unauthorized disclosure violates this principle. While nonmaleficence and
beneficence are important, the primary violation is against autonomy, as it disregards the
patient's control over personal data.
Page 4
