MLA SB A Qu estion B an k
Idiopathic Thrombocytopenic Purpura (ITP)
50 single best answer questions — Domain 6: Conditions, Body system: Blood and Lymph
Based on the GMC Medical Licensing Assessment (MLA) content map — applicable from September 2026
,BLOOD AND LY MPH Question 1 of 50
Immune Thrombocytopenia (ITP) Immune thrombocytopenia (ITP) in adults
A 32-year-old woman presents with widespread petechiae and easy bruising over the past week, with no other symptoms. Full blood count
shows an isolated platelet count of 18 x10^9/L, with normal haemoglobin and white cell count. What is the most likely diagnosis?
A Acute myeloid leukaemia
B Thrombotic thrombocytopenic purpura
C Immune thrombocytopenia (ITP)
D Disseminated intravascular coagulation
E Vitamin B12 deficiency
Select the single best answer.
,BLOOD AND LY MPH Question 1 of 50 — Answer
Immune Thrombocytopenia (ITP) Immune thrombocytopenia (ITP) in adults
A 32-year-old woman presents with widespread petechiae and easy bruising over the past week, with no other symptoms. Full blood count shows an isolated platelet count
of 18 x10^9/L, with normal haemoglobin and white cell count. What is the most likely diagnosis?
A Acute myeloid leukaemia
B Thrombotic thrombocytopenic purpura
C Immune thrombocytopenia (ITP) ✓ Correct
D Disseminated intravascular coagulation
E Vitamin B12 deficiency
EXPLANATION
ITP typically presents with isolated thrombocytopenia (with normal haemoglobin and white cell count) in an otherwise well patient, caused by autoimmune
destruction of platelets by antiplatelet antibodies.
, BLOOD AND LY MPH Question 2 of 50
Immune Thrombocytopenia (ITP) Immune thrombocytopenia (ITP) in adults
A 28-year-old woman with new ITP undergoes a thorough history and examination. Which additional finding, if present, would suggest a
secondary cause of her ITP rather than primary (idiopathic) disease?
A Mild bruising only
B Isolated thrombocytopenia with no other abnormality
C Features suggestive of an underlying condition such as HIV, hepatitis C, or systemic lupus erythematosus
D Petechiae on examination
E A normal physical examination otherwise
Select the single best answer.
Idiopathic Thrombocytopenic Purpura (ITP)
50 single best answer questions — Domain 6: Conditions, Body system: Blood and Lymph
Based on the GMC Medical Licensing Assessment (MLA) content map — applicable from September 2026
,BLOOD AND LY MPH Question 1 of 50
Immune Thrombocytopenia (ITP) Immune thrombocytopenia (ITP) in adults
A 32-year-old woman presents with widespread petechiae and easy bruising over the past week, with no other symptoms. Full blood count
shows an isolated platelet count of 18 x10^9/L, with normal haemoglobin and white cell count. What is the most likely diagnosis?
A Acute myeloid leukaemia
B Thrombotic thrombocytopenic purpura
C Immune thrombocytopenia (ITP)
D Disseminated intravascular coagulation
E Vitamin B12 deficiency
Select the single best answer.
,BLOOD AND LY MPH Question 1 of 50 — Answer
Immune Thrombocytopenia (ITP) Immune thrombocytopenia (ITP) in adults
A 32-year-old woman presents with widespread petechiae and easy bruising over the past week, with no other symptoms. Full blood count shows an isolated platelet count
of 18 x10^9/L, with normal haemoglobin and white cell count. What is the most likely diagnosis?
A Acute myeloid leukaemia
B Thrombotic thrombocytopenic purpura
C Immune thrombocytopenia (ITP) ✓ Correct
D Disseminated intravascular coagulation
E Vitamin B12 deficiency
EXPLANATION
ITP typically presents with isolated thrombocytopenia (with normal haemoglobin and white cell count) in an otherwise well patient, caused by autoimmune
destruction of platelets by antiplatelet antibodies.
, BLOOD AND LY MPH Question 2 of 50
Immune Thrombocytopenia (ITP) Immune thrombocytopenia (ITP) in adults
A 28-year-old woman with new ITP undergoes a thorough history and examination. Which additional finding, if present, would suggest a
secondary cause of her ITP rather than primary (idiopathic) disease?
A Mild bruising only
B Isolated thrombocytopenia with no other abnormality
C Features suggestive of an underlying condition such as HIV, hepatitis C, or systemic lupus erythematosus
D Petechiae on examination
E A normal physical examination otherwise
Select the single best answer.
