MLA SB A Qu estion B an k
Abnormal Blood Film
50 single best answer questions — Domain 6: Conditions, Body system: Blood and Lymph
Based on the GMC Medical Licensing Assessment (MLA) content map — applicable from September 2026
,BLOOD AND LY MPH Question 1 of 50
Abnormal Blood Film Haemolytic uraemic syndrome
A 4-year-old boy develops bloody diarrhoea after eating undercooked beef, followed 5 days later by pallor, oliguria, and bruising. Blood
tests show anaemia, thrombocytopenia, and acute kidney injury. What is the most likely diagnosis?
A Thrombotic thrombocytopenic purpura
B Immune thrombocytopenic purpura
C Disseminated intravascular coagulation
D Haemolytic uraemic syndrome
E Henoch-Schönlein purpura
Select the single best answer.
,BLOOD AND LY MPH Question 1 of 50 — Answer
Abnormal Blood Film Haemolytic uraemic syndrome
A 4-year-old boy develops bloody diarrhoea after eating undercooked beef, followed 5 days later by pallor, oliguria, and bruising. Blood tests show anaemia,
thrombocytopenia, and acute kidney injury. What is the most likely diagnosis?
A Thrombotic thrombocytopenic purpura
B Immune thrombocytopenic purpura
C Disseminated intravascular coagulation
D Haemolytic uraemic syndrome ✓ Correct
E Henoch-Schönlein purpura
EXPLANATION
The triad of microangiopathic haemolytic anaemia, thrombocytopenia, and acute kidney injury following a diarrhoeal illness (often bloody, from Shiga-toxin producing
E. coli) is classic for typical (D+) haemolytic uraemic syndrome.
, BLOOD AND LY MPH Question 2 of 50
Abnormal Blood Film Haemolytic uraemic syndrome
Typical haemolytic uraemic syndrome (D+ HUS) in children is most commonly caused by infection with which organism?
A Campylobacter jejuni alone
B Streptococcus pneumoniae
C Shiga-toxin producing Escherichia coli (E. coli O157:H7)
D Clostridioides difficile
E Salmonella typhi
Select the single best answer.
Abnormal Blood Film
50 single best answer questions — Domain 6: Conditions, Body system: Blood and Lymph
Based on the GMC Medical Licensing Assessment (MLA) content map — applicable from September 2026
,BLOOD AND LY MPH Question 1 of 50
Abnormal Blood Film Haemolytic uraemic syndrome
A 4-year-old boy develops bloody diarrhoea after eating undercooked beef, followed 5 days later by pallor, oliguria, and bruising. Blood
tests show anaemia, thrombocytopenia, and acute kidney injury. What is the most likely diagnosis?
A Thrombotic thrombocytopenic purpura
B Immune thrombocytopenic purpura
C Disseminated intravascular coagulation
D Haemolytic uraemic syndrome
E Henoch-Schönlein purpura
Select the single best answer.
,BLOOD AND LY MPH Question 1 of 50 — Answer
Abnormal Blood Film Haemolytic uraemic syndrome
A 4-year-old boy develops bloody diarrhoea after eating undercooked beef, followed 5 days later by pallor, oliguria, and bruising. Blood tests show anaemia,
thrombocytopenia, and acute kidney injury. What is the most likely diagnosis?
A Thrombotic thrombocytopenic purpura
B Immune thrombocytopenic purpura
C Disseminated intravascular coagulation
D Haemolytic uraemic syndrome ✓ Correct
E Henoch-Schönlein purpura
EXPLANATION
The triad of microangiopathic haemolytic anaemia, thrombocytopenia, and acute kidney injury following a diarrhoeal illness (often bloody, from Shiga-toxin producing
E. coli) is classic for typical (D+) haemolytic uraemic syndrome.
, BLOOD AND LY MPH Question 2 of 50
Abnormal Blood Film Haemolytic uraemic syndrome
Typical haemolytic uraemic syndrome (D+ HUS) in children is most commonly caused by infection with which organism?
A Campylobacter jejuni alone
B Streptococcus pneumoniae
C Shiga-toxin producing Escherichia coli (E. coli O157:H7)
D Clostridioides difficile
E Salmonella typhi
Select the single best answer.
