NRNP 6552 Advanced Nurse Practice in Reproductive Health
NRNP 6552 - Final Exam Prep
400 Questions and Answers with Rationales
Welcome to the NRNP 6552 Advanced Nurse Practice in Reproductive Health Final
Exam Preparation for the 2026/2027 Academic Year. This comprehensive resource
contains 400 original, verified questions aligned with the Walden University
NRNP 6552 course objectives.
The exam covers key domains of advanced reproductive health practice, including:
- Normal Pregnancy and Antepartum Care
- Prenatal Screening and Diagnostic Testing
- Complications of Pregnancy
- Gynecologic Conditions and Disorders
- Breast Health and Breast Cancer
- Reproductive Cancers
- Contraception and Family Planning
- Menopause and Perimenopause
- Sexual Health and Intimate Partner Violence
- Pharmacotherapy in Reproductive Health
- Ethical and Legal Issues
Every question has been written originally to reinforce the official NRNP 6552
course objectives, supporting actual exam readiness and clinical proficiency in
advanced reproductive health nursing practice. Each item pairs a clinically
accurate stem with four options and a concise rationale grounded in evidence-based
practice and current clinical guidelines.
Work through the test bank systematically, review rationales for incorrect
answers, and build confidence for your final examination. Good luck!
DOMAIN 1: NORMAL PREGNANCY AND ANTEPARTUM CARE (Questions 1-80)
1. At what time during pregnancy does nausea typically occur?
A. 2-4 weeks' gestation
B. 6-8 weeks' gestation
C. 10-12 weeks' gestation
D. 14-16 weeks' gestation
Correct Answer: B
,Rationale: Nausea and vomiting of pregnancy typically begin at 6-8 weeks' gestation,
peak at 9 weeks, and usually resolve by 12-14 weeks.
2. A 40-year-old white female whose mother died from ovarian cancer asks the nurse
practitioner if there is a way to prevent ovarian cancer. What is the best response?
A. There are factors that inhibit ovulation that can reduce the risk of developing ovarian
cancer
B. A prophylactic oophorectomy is recommended for all women with a family history
C. Oral contraceptives increase the risk of ovarian cancer
D. There is no way to prevent ovarian cancer
Correct Answer: A
Rationale: Factors that inhibit ovulation (pregnancy, breastfeeding, oral contraceptives)
reduce ovarian cancer risk.
3. Why are most cases of ovarian cancer diagnosed when the disease has already
reached an advanced stage?
A. The symptoms are vague
B. The disease progresses rapidly
C. Screening tests are not available
D. Women do not seek care early
Correct Answer: A
Rationale: Ovarian cancer symptoms are vague (bloating, pelvic pain, early satiety,
urinary urgency), leading to late diagnosis.
4. Sally, who is 18 weeks pregnant, had a maternal serum alpha-fetoprotein level done.
The results are elevated. What is the meaning of an elevated MSAFP level?
A. There is an increased risk that the fetus has an open neural tube defect
B. There is an increased risk of Down syndrome
C. The pregnancy is at risk for preterm delivery
D. The fetus has a cardiac defect
Correct Answer: A
Rationale: Elevated MSAFP is associated with open neural tube defects (spina bifida,
anencephaly) and abdominal wall defects.
5. A 24-year-old female insists on having a screening mammogram. The patient is
concerned because her mother has fibrocystic breast disease. The NP would be accurate if
she tells the patient that the major risk factor for development of breast cancer in women
is:
A. First full-term pregnancy after 30 years of age
B. Family history of fibrocystic breast disease
C. Use of oral contraceptives
D. Early menopause
Correct Answer: A
Rationale: Late first full-term pregnancy (>30 years) is a significant risk factor for breast
cancer.
,6. Which of the following drugs should be used with extreme caution in breastfeeding
mothers?
A. Phenobarbital
B. Acetaminophen
C. Ibuprofen
D. Penicillin
Correct Answer: A
Rationale: Phenobarbital is excreted in breast milk and can cause sedation in infants; it
should be used with extreme caution.
7. During pregnancy, it is important to be physically active. The NP should encourage her
pregnant patient who has a very sedentary lifestyle to:
A. Start walking daily and slowly build up distance
B. Start running immediately
C. Begin high-intensity interval training
D. Avoid exercise during pregnancy
Correct Answer: A
Rationale: Sedentary pregnant women should start with low-impact activities like walking
and gradually increase.
8. After how many weeks' gestation is a pregnancy loss considered a fetal death or
stillbirth?
A. 16 weeks
B. 18 weeks
C. 20 weeks
D. 22 weeks
Correct Answer: C
Rationale: In the United States, fetal death or stillbirth is defined as death at 20 weeks'
gestation or later.
9. In respect to an evidentiary examination, when should it be done?
A. Within 24 hours of the incident
B. Within 72 hours of the incident
C. The time frame within which it must take place depends on local standards
D. Immediately after the incident
Correct Answer: C
Rationale: The timeframe for evidentiary examinations varies by jurisdiction and local
standards.
10. What had been a significant problem in medical research well into the 1990s?
A. The lack of funding for research studies
B. The lack of representation of women in research trials
C. The lack of diversity in research participants
D. The lack of ethical oversight in research
, Correct Answer: B
Rationale: Women were historically underrepresented in clinical research trials until the
NIH Revitalization Act of 1993.
11. The most effective means of obtaining the history of abuse is to use a communication
model that:
A. Uses a structured questionnaire with yes/no answers
B. Allows the patient to talk without interruption and with time to relate, emphasize, and
repeat her full story
C. Focuses only on physical injuries
D. Limits the conversation to 15 minutes
Correct Answer: B
Rationale: A patient-centered, non-judgmental approach allowing the patient to tell her
story is most effective in obtaining abuse history.
12. What is the leading preventable cause of death across all populations in the US?
A. Alcohol
B. Obesity
C. Tobacco
D. Physical inactivity
Correct Answer: C
Rationale: Tobacco use is the leading preventable cause of death in the United States.
13. The most common sites of metastatic spread of invasive breast cancer include all of the
following except:
A. Bone
B. Liver
C. Brain
D. Pituitary
Correct Answer: D
Rationale: Common metastatic sites for breast cancer are bone, liver, lungs, and brain; the
pituitary is not a common site.
14. Endometrial cancer occurs most frequently in:
A. Premenopausal women in their 30s
B. Perimenopausal women in their 40s
C. Postmenopausal women between the ages of 60-65
D. Women of any age with a history of hormone use
Correct Answer: C
Rationale: Endometrial cancer most commonly occurs in postmenopausal women aged 60-
65.
15. A 30-year-old bisexual female is asking about treatment for uterine fibroids. The best
treatment is:
A. Hysterectomy
NRNP 6552 - Final Exam Prep
400 Questions and Answers with Rationales
Welcome to the NRNP 6552 Advanced Nurse Practice in Reproductive Health Final
Exam Preparation for the 2026/2027 Academic Year. This comprehensive resource
contains 400 original, verified questions aligned with the Walden University
NRNP 6552 course objectives.
The exam covers key domains of advanced reproductive health practice, including:
- Normal Pregnancy and Antepartum Care
- Prenatal Screening and Diagnostic Testing
- Complications of Pregnancy
- Gynecologic Conditions and Disorders
- Breast Health and Breast Cancer
- Reproductive Cancers
- Contraception and Family Planning
- Menopause and Perimenopause
- Sexual Health and Intimate Partner Violence
- Pharmacotherapy in Reproductive Health
- Ethical and Legal Issues
Every question has been written originally to reinforce the official NRNP 6552
course objectives, supporting actual exam readiness and clinical proficiency in
advanced reproductive health nursing practice. Each item pairs a clinically
accurate stem with four options and a concise rationale grounded in evidence-based
practice and current clinical guidelines.
Work through the test bank systematically, review rationales for incorrect
answers, and build confidence for your final examination. Good luck!
DOMAIN 1: NORMAL PREGNANCY AND ANTEPARTUM CARE (Questions 1-80)
1. At what time during pregnancy does nausea typically occur?
A. 2-4 weeks' gestation
B. 6-8 weeks' gestation
C. 10-12 weeks' gestation
D. 14-16 weeks' gestation
Correct Answer: B
,Rationale: Nausea and vomiting of pregnancy typically begin at 6-8 weeks' gestation,
peak at 9 weeks, and usually resolve by 12-14 weeks.
2. A 40-year-old white female whose mother died from ovarian cancer asks the nurse
practitioner if there is a way to prevent ovarian cancer. What is the best response?
A. There are factors that inhibit ovulation that can reduce the risk of developing ovarian
cancer
B. A prophylactic oophorectomy is recommended for all women with a family history
C. Oral contraceptives increase the risk of ovarian cancer
D. There is no way to prevent ovarian cancer
Correct Answer: A
Rationale: Factors that inhibit ovulation (pregnancy, breastfeeding, oral contraceptives)
reduce ovarian cancer risk.
3. Why are most cases of ovarian cancer diagnosed when the disease has already
reached an advanced stage?
A. The symptoms are vague
B. The disease progresses rapidly
C. Screening tests are not available
D. Women do not seek care early
Correct Answer: A
Rationale: Ovarian cancer symptoms are vague (bloating, pelvic pain, early satiety,
urinary urgency), leading to late diagnosis.
4. Sally, who is 18 weeks pregnant, had a maternal serum alpha-fetoprotein level done.
The results are elevated. What is the meaning of an elevated MSAFP level?
A. There is an increased risk that the fetus has an open neural tube defect
B. There is an increased risk of Down syndrome
C. The pregnancy is at risk for preterm delivery
D. The fetus has a cardiac defect
Correct Answer: A
Rationale: Elevated MSAFP is associated with open neural tube defects (spina bifida,
anencephaly) and abdominal wall defects.
5. A 24-year-old female insists on having a screening mammogram. The patient is
concerned because her mother has fibrocystic breast disease. The NP would be accurate if
she tells the patient that the major risk factor for development of breast cancer in women
is:
A. First full-term pregnancy after 30 years of age
B. Family history of fibrocystic breast disease
C. Use of oral contraceptives
D. Early menopause
Correct Answer: A
Rationale: Late first full-term pregnancy (>30 years) is a significant risk factor for breast
cancer.
,6. Which of the following drugs should be used with extreme caution in breastfeeding
mothers?
A. Phenobarbital
B. Acetaminophen
C. Ibuprofen
D. Penicillin
Correct Answer: A
Rationale: Phenobarbital is excreted in breast milk and can cause sedation in infants; it
should be used with extreme caution.
7. During pregnancy, it is important to be physically active. The NP should encourage her
pregnant patient who has a very sedentary lifestyle to:
A. Start walking daily and slowly build up distance
B. Start running immediately
C. Begin high-intensity interval training
D. Avoid exercise during pregnancy
Correct Answer: A
Rationale: Sedentary pregnant women should start with low-impact activities like walking
and gradually increase.
8. After how many weeks' gestation is a pregnancy loss considered a fetal death or
stillbirth?
A. 16 weeks
B. 18 weeks
C. 20 weeks
D. 22 weeks
Correct Answer: C
Rationale: In the United States, fetal death or stillbirth is defined as death at 20 weeks'
gestation or later.
9. In respect to an evidentiary examination, when should it be done?
A. Within 24 hours of the incident
B. Within 72 hours of the incident
C. The time frame within which it must take place depends on local standards
D. Immediately after the incident
Correct Answer: C
Rationale: The timeframe for evidentiary examinations varies by jurisdiction and local
standards.
10. What had been a significant problem in medical research well into the 1990s?
A. The lack of funding for research studies
B. The lack of representation of women in research trials
C. The lack of diversity in research participants
D. The lack of ethical oversight in research
, Correct Answer: B
Rationale: Women were historically underrepresented in clinical research trials until the
NIH Revitalization Act of 1993.
11. The most effective means of obtaining the history of abuse is to use a communication
model that:
A. Uses a structured questionnaire with yes/no answers
B. Allows the patient to talk without interruption and with time to relate, emphasize, and
repeat her full story
C. Focuses only on physical injuries
D. Limits the conversation to 15 minutes
Correct Answer: B
Rationale: A patient-centered, non-judgmental approach allowing the patient to tell her
story is most effective in obtaining abuse history.
12. What is the leading preventable cause of death across all populations in the US?
A. Alcohol
B. Obesity
C. Tobacco
D. Physical inactivity
Correct Answer: C
Rationale: Tobacco use is the leading preventable cause of death in the United States.
13. The most common sites of metastatic spread of invasive breast cancer include all of the
following except:
A. Bone
B. Liver
C. Brain
D. Pituitary
Correct Answer: D
Rationale: Common metastatic sites for breast cancer are bone, liver, lungs, and brain; the
pituitary is not a common site.
14. Endometrial cancer occurs most frequently in:
A. Premenopausal women in their 30s
B. Perimenopausal women in their 40s
C. Postmenopausal women between the ages of 60-65
D. Women of any age with a history of hormone use
Correct Answer: C
Rationale: Endometrial cancer most commonly occurs in postmenopausal women aged 60-
65.
15. A 30-year-old bisexual female is asking about treatment for uterine fibroids. The best
treatment is:
A. Hysterectomy
