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Test Bank-Pharmacotherapeutics for Advanced Practice-A Practical Approach 5th Edition Arcangelo, Peterson,Wilbur & Kang(2022), All Chapters 1-56

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Test Bank-Pharmacotherapeutics for Advanced Practice-A Practical Approach 5th Edition Arcangelo, Peterson,Wilbur & Kang(2022), All Chapters 1-56Chapter 1 Issues for the Practitioner in Drug Therapy MULTIPLE CHOICE 1. Nurse practitioner prescriptive authority is regulated by: A. The National Council of State Boards of Nursing B. The U.S. Drug Enforcement Administration C. The State Board of Nursing for each state D. The State Board of Pharmacy ANS: C PTS: 1 2. Physician Assistant (PA) prescriptive authority is regulated by: A. The National Council of State Boards of Nursing B. The U.S. Drug Enforcement Administration C. The State Board of Nursing D. The State Board of Medical Examiners ANS: D PTS: 1 3. Clinical judgment in prescribing includes: A. Factoring in the cost to the patient of the medication prescribed B. Always prescribing the newest medication available for the disease process C. Handing out drug samples to poor patients D. Prescribing all generic medications to cut costs ANS: A PTS: 1 4. Criteria for choosing an effective drug for a disorder include: A. Asking the patient what drug they think would work best for them B. Consulting nationally recognized guidelines for disease management C. Prescribing medications that are available as samples before writing a prescription D. Following U.S. Drug Enforcement Administration (DEA) guidelines for prescribing ANS: B PTS: 1 5. Nurse practitioner practice may thrive under health-care reform due to: A. The demonstrated ability of nurse practitioners to control costs and improve patient outcomes B. The fact that nurse practitioners will be able to practice independently C. The fact that nurse practitioners will have full reimbursement under health-care reform D. The ability to shift accountability for Medicaid to the state level ANS: A PTS: 1 Chapter 2.Pharmacokinetic Basis of Therapeutics and Pharmacodynamic MULTIPLE CHOICE 1. A patient's nutritional intake and lab work reflects hypoalbuminemia. This is critical to prescribing because: A. Distribution of drugs to target tissue may be affected B. The solubility of the drug will not match the site of absorption C. There will be less free drug available to generate an effect D. Drugs bound to albumin are readily excreted by the kidney ANS: A PTS: 1 2. Drugs that have a significant first-pass effect: A. Must be given by the enteral (oral) route only B. Bypass the hepatic circulation C. Are rapidly metabolized by the liver and may have little if any desired action D. Are converted by the liver to more active and fat-soluble forms ANS: C PTS: 1 3. The route of excretion of a volatile drug will likely be: A. The kidneys B. The lungs C. The bile and feces D. The skin ANS: B PTS: 1 4. Medroxyprogesterone (Depo Provera) is prescribed IM to create a storage reservoir of the drug. Storage reservoirs: A. Assure that the drug will reach its intended target tissue B. Are the reason for giving loading doses C. Increase the length of time a drug is available and active D. Are most common in collagen tissues ANS: C PTS: 1 5. The NP chooses to give cephalexin every 8 hours based on knowledge of the drug's: A. Propensity to go to the target receptor B. Biological half-life C. Pharmacodynamics D. Safety and side effects ANS: B PTS: 1 6. Azithromycin dosing requires the first day's dose be twice those of the other 4 days of the prescription. This is considered a loading dose. A loading dose: A. Rapidly achieves drug levels in the therapeutic range B. Requires four to five half-lives to attain C. Is influenced by renal function D. Is directly related to the drug circulating to the target tissues ANS: A PTS: 1 7. The point in time on the drug concentration curve that indicates the first sign of a therapeutic effect is the: A. Minimum adverse effect level B. Peak of action C. Onset of action D. Therapeutic range ANS: C PTS: 1 8. Phenytoin requires a trough level be drawn. Peak and trough levels are done: A. When the drug has a wide therapeutic range B. When the drug will be administered for a short time only C. When there is a high correlation between the dose and saturation of receptor sites D. To determine if a drug is in the therapeutic range ANS: D PTS: 1 9. A laboratory result indicates the peak level for a drug is above the minimum toxic concentration. This means that the: A. Concentration will produce therapeutic effects B. Concentration will produce an adverse response C. Time between doses must be shortened D. Duration of action of the drug is too long ANS: B PTS: 1 10. Drugs that are receptor agonists may demonstrate what property? A. Irreversible binding to the drug receptor site B. Up-regulation with chronic use C. Desensitization or down-regulation with continuous use D. Inverse relationship between drug concentration and drug action ANS: C PTS: 1 11. Drugs that are receptor antagonists, such as beta blockers, may cause: A. Down-regulation of the drug receptor B. An exaggerated response if abruptly discontinued C. Partial blockade of the effects of agonist drugs D. An exaggerated response to competitive drug agonists ANS: B PTS: 1 12. Factors that affect gastric drug absorption include: A. Liver enzyme activity B. Protein-binding properties of the drug molecule C. Lipid solubility of the drug D. Ability to chew and swallow ANS: C PTS: 1 13. Drugs administered via intravenous (IV) route: A. Need to be lipid soluble in order to be easily absorbed B. Begin distribution into the body immediately C. Are easily absorbed if they are nonionized D. May use pinocytosis to be absorbed ANS: B PTS: 1 14. When a medication is added to a regimen for a synergistic effect, the combined effect of the drugs is: A. The sum of the effects of each drug individually B. Greater than the sum of the effects of each drug individually C. Less than the effect of each drug individually D. Not predictable, as it varies with each individual ANS: B PTS: 1 15. Which of the following statements about bioavailability is true? A. Bioavailability issues are especially important for drugs with narrow therapeutic ranges or sustained release mechanisms. B. All brands of a drug have the same bioavailability. C. Drugs that are administered more than once a day have greater bioavailability than drugs given once daily. D. Combining an active drug with an inert substance does not affect bioavailability. ANS: A PTS: 1 16. Which of the following statements about the major distribution barriers (blood-brain or fetal-placental) is true? A. Water soluble and ionized drugs cross these barriers rapidly. B. The blood-brain barrier slows the entry of many drugs into and from brain cells. C. The fetal-placental barrier protects the fetus from drugs taken by the mother. D. Lipid soluble drugs do not pass these barriers and are safe for pregnant women. ANS: B PTS: 1 17. Drugs are metabolized mainly by the liver via Phase I or Phase II reactions. The purpose of both of these types of reactions is to: A. Inactivate prodrugs before they can be activated by target tissues B. Change the drugs so they can cross plasma membranes C. Change drug molecules to a form that an excretory organ can excrete D. Make these drugs more ionized and polar to facilitate excretion ANS: C PTS: 1 18. Once they have been metabolized by the liver, the metabolites may be: A. More active than the parent drug B. Less active than the parent drug C. Totally “deactivated” so that they are excreted without any effect D. All of the above ANS: D PTS: 1 19. All drugs continue to act in the body until th

Content preview

TESTBANK

Pharmacotherapeutics For Advanced Practice APractical Ap mo mo mo mo mo mo




proach 5th Edition By Arcangelo; Wilbur; Ch 1 to 56 mo mo mo mo mo mo mo mo mo




Tableofcontent m
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Chapter I Issues for the Practitioner in Drug Therapy
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Chapter 2 Pharmacokinetic Basis of Therapeutics and Pharmacodynamic Principles
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Chapter 3 Impact of Drug Interactions and Adverse Events on Therapeutics
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Chapter 4 Principles of Pharmacotherapy in Pediatrics, Pregnancy, and Lactation
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Chapter 5 Pharmacotherapy Principles in Older Adults
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Chapter 6 Principles of Antimicrobial Therapy
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Chapter 7 Pharmacogenomies
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Chapter 8 The Economics of Pharmacotherapeutics
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Chapter 9 Pharmacotherapy of Pain Management
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Chapter I0 Pain Management in Opioid Use Disorder (OUD) Patients
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Chapter 11 Cannabis and Pain Management
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Chapter 12 Contact Dermatitis
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Chapter 13 Fungal, Viral, and Bacterial Infections of the Skin C
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hapter 14 Psoriasis
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Chapter I5 Acne Vulgaris and Rosacea
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Chapter 16 Ophthalmic Disorders
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Chapter I7 Otitis Media and Otitis Externa C
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hapter I8 Hypertension
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Chapter I9 Hyperlipidemia
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Chapter 20 Chronic Stable Angina and Myocardial Infarction
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mo Chapter 2I Heart Failure
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Chapter 22 Arrhythmias
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Chapter 23 Respiratory Infections
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Chapter 24 Asthma and Chronic Obstructive Pulmonary Disease
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Chapter 25 Gastric, Functional, and Inflammatory Boẉel Disorders
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Chapter 26 Gastroesophageal Reflux Disease and Peptic Ulcer Disease
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mo Chapter 27 Liver Diseases
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,Chapter 28 Urinary Tract Infection
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Chapter 29 Prostatic Disorders and Erectile Dysfunction
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Chapter 30 Overactive Bladder
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Chapter 3I Sexually Transmitted Infection
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Chapter 32 Osteoarthritis and Gout
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Chapter 33 Osteoporosis mo mo




Chapter 34 Rheumatoid Arthritis
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Chapter 35 Headaches mo mo




Chapter 36 Seizure Disorders
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Chapter 37 Alzheimer's Disease
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Chapter 38 Parkinson's diseas
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Chapter 39 Major Depressive Disorder and Bipolar Disorders
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Chapter 40 Anxiety Disorders
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Chapter 41 Sleep Disorders
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Chapter 42 Attention Deficit Hyperactivity Disorder
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Chapter 43 Substance Use Disorders
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Chapter 44 Diabetes Mellitus
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Chapter 45 Thyroid and Parathyroid Disorders
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Chapter 46 Allergies and Allergic Reactions C
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hapter47 Human Immunodeficiency Virus
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Chapter 48 Organ Transplantation
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Chapter 49 Thromboembolic Disorders Cha
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pter 50 Anemias
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Chapter 5l Immunizations mo mo mo




Chapter 52 Smoking Cessation C
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hapter 53 Ẉeight Loss
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Chapter 54 Contraception mo mo




Chapter 55 Menopause mo mo




Chapter 56 Vaginitis m o m o

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Chapter 1 Issues for the Practitioner in Drug Therapy
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MULTIPLE CHOICE mo




1. Nurse practitioner prescriptive authority is regulated by:
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A. The National Council of State Boards of Nursing
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B. The U.S. Drug Enforcement Administration
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C. The State Board of Nursing for each state
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D. The State Board of Pharmacy
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ANSWER: C m o PTS: 1 m o




2. Physician Assistant (PA) prescriptive authority is regulated by:
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A. The National Council of State Boards of Nursing
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B. The U.S. Drug Enforcement Administration
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C. The State Board of Nursing
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D. The State Board of Medical Examiners
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ANSWER: D m o PTS: 1 m o




3. Clinical judgment in prescribing includes:
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A. Factoring in the cost to the patient of the medication prescribed
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B. Alẉays prescribing the neẉest medication available for the disease process
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C. Handing out drug samples to poor patients mo mo mo mo mo mo




D. Prescribing all generic medications to cut costs mo mo mo mo mo mo




ANSWER: A m o PTS: 1 m o




4. Criteria for choosing an effective drug for a disorder include:
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A. Asking the patient ẉhat drug they think ẉould ẉork best for them
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B. Consulting nationally recognized guidelines for disease management
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C. Prescribing medications that are available as samples before ẉriting a prescription
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D. Folloẉing U.S. Drug Enforcement Administration (DEA) guidelin
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es for prescribing
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ANSWER: B m o PTS: 1 m o




5. Nurse practitioner practice may thrive under health-care reform due to:
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A. The demonstrated ability of nurse practitioners to control costs and improve
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B. The fact that nurse practitioners ẉill be able to practice independently
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C. The fact that nurse practitioners ẉill have full reimbursement under heal
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D. The ability to shift accountability for Medicaid to the state level
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ANSWER: A m o PTS: 1 m o

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Chapter 2.Pharmacokinetic Basis of Therapeutics and Pharmacodynamic
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MULTIPLE CHOICE mo




1. A patient's nutritional intake and lab ẉork reflects hypoalbuminemia. This is cr
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itical to prescribing because:
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A. Distribution of drugs to target tissue may be affected mo mo mo mo mo mo mo mo




B. The solubility of the drug ẉill not match the site of absorption
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C. There ẉill be less free drug available to generate an effect
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D. Drugs bound to albumin are readily excreted by the kidney
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ANSWER: A m o PTS: 1 m o




2. Drugs that have a significant first-pass effect:
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A. Must be given by the enteral (oral) route only
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B. Bypass the hepatic circulation mo mo mo




C. Are rapidly metabolized by the liver and may have little if any desired action
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D. Are converted by the liver to more active and fat-soluble forms
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ANSWER: C m o PTS: 1 m o




3. The route of excretion of a volatile drug ẉill likely be:
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ANSWER: B m o PTS: 1 m o




4. Medroxyprogesterone (Depo Provera) is prescribed IM to create a storage reservoi mo mo mo mo mo mo mo mo mo mo




r of the drug. Storage reservoirs:
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A. Assure that the drug ẉill reach its intended target tissue
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B. Are the reason for giving loading doses
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C. Increase the length of time a drug is available and active
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D. Are most common in collagen tissues
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ANSWER: C m o PTS: 1 m o




5. The NP chooses to give cephalexin every 8 hours based on knoẉledge of the drug's:
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A. Propensity to go to the target receptor mo mo mo mo mo mo




B. Biological half-life mo




C. Pharmacodynamics
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ANSWER: B m o PTS: 1 m o




6. Azithromycin dosing requires the first day's dose be tẉice those of the other 4 day
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s of the prescription. This is considered a loading dose. A loading dose:
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A. Rapidly achieves drug levels in the therapeutic range
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B. Requires four to five half-lives to attain mo mo mo mo mo mo




C. Is influenced by renal function
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Connected book
 image
ARCANGELO, Virginia Poole Arcangelo, PhD Crnp, Andrew M Peterson, Pharmd PhD, Veronica Wilbur, Jennifer A Reinhold Pharmacotherapeutic Advanced Practice 5
Publisher: Unknown ISBN: 9781975160593 Edition: Unknown

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