NR 566
NR 566 MIDTERM EXAM QUESTIONS AND ANSWERS
Which non-amphetamines are FDA approved for weight loss that have
lower abuse risk? - correct answer Phentermine and Diethylpropion
How does Phentermine and Diethylpropion promote weight loss? -
correct answer -Promote weight loss by decreasing appetite
-They are central nervous system (CNS) stimulants that suppress
appetite by increasing the availability of norepinephrine at receptors in
the brain
What is the maximum recommended duration of use for non-
amphetamines? - correct answer 3 months or less
What drug schedule are Phentermine and Diethylpropion under? - correct
answer Schedule IV
,NR 566
What labs should be monitored with Phentermine and Diethylpropion?
What condition should we screen for? - correct answer -baseline CMP
(watch electrolytes and creatinine)
-screen for depression
Phentermine adverse effects - correct answer -increase HR and BP
-dry mouth and constipation
What is role of topiramate in weight loss? - correct answer Increases satiety
What are some Phentermine/topiramate contraindications for use? -
correct answer not approved in children and contraindicated with severe
hepatic impairment
How should we educate patient to take Phentermine/topiramate to
avoid insomnia? - correct answer given before 1600
What are some high-risk patient conditions that we should use
Phentermine/topiramate with caution? - correct answer hx drug abuse,
glaucoma, pregnant, HTN, hyperthyroidism
Phentermine/topiramate adverse effects - correct answer insomnia,
nervousness, anxiety, depression, blurred vision
,NR 566
Which of the following would be a contraindication to prescribing
phentermine/topiramate? Select all that apply. - correct answer A)
Glaucoma
B) Hypothyroidism
C) Hypertension
D) Hyperthyroidism
E) Vitamin D Deficiency
F) A, B, E
ANSWER: A,C,D
Orlistat is a lipase inhibitor that acts on the _________ and reduces
absorption of fat by 30%. - correct answer GI tract
Take multivitamin ___hours before/after to supplement fat-soluble
vitamins that may not be absorbed well when taking Orlistat. - correct
answer 2
Orlistat is OTC as 60 mg TID with meals. Not approved in children
<____. - correct answer 12
Orlistat results in the least amount of weight loss of all. How much? -
correct answer 2-3% body weight (7 lbs in year)
, NR 566
Orlistat adverse effects - correct answer Fecal incontinence, oily rectal
leakage, flatus, abdominal cramps. liver damage (light-colored stools,
dark urine, fatigue, jaundice, anorexia)
When is Orlistat contraindicated? - correct answer In those with
malabsorption syndrome or cholestasis
What vitamin deficiency are we concerned about when taking
Orlistat...especially if the patient is on coumadin? - correct answer Monitor
Coumadin as Vitamin K deficiency may occur and intensify effect of
Coumadin.
A patient with a BMI of 27 would be considered: - correct answer
overweight
Lorcaserin adverse effects - correct answer headache, URI, back pain,
hypoglycemia (in DM), blood dyscrasias, cognitive impairment,
psychiatric disorders, priapism, pulmonary hypertension, and valvular
heart disease
Lorcaserin MOA - correct answer Reduces waist circumference, fasting
glucose, insulin, total cholesterol, LDL, triglycerides
When is Lorcaserin contraindicated? - correct answer CrCl <30
NR 566 MIDTERM EXAM QUESTIONS AND ANSWERS
Which non-amphetamines are FDA approved for weight loss that have
lower abuse risk? - correct answer Phentermine and Diethylpropion
How does Phentermine and Diethylpropion promote weight loss? -
correct answer -Promote weight loss by decreasing appetite
-They are central nervous system (CNS) stimulants that suppress
appetite by increasing the availability of norepinephrine at receptors in
the brain
What is the maximum recommended duration of use for non-
amphetamines? - correct answer 3 months or less
What drug schedule are Phentermine and Diethylpropion under? - correct
answer Schedule IV
,NR 566
What labs should be monitored with Phentermine and Diethylpropion?
What condition should we screen for? - correct answer -baseline CMP
(watch electrolytes and creatinine)
-screen for depression
Phentermine adverse effects - correct answer -increase HR and BP
-dry mouth and constipation
What is role of topiramate in weight loss? - correct answer Increases satiety
What are some Phentermine/topiramate contraindications for use? -
correct answer not approved in children and contraindicated with severe
hepatic impairment
How should we educate patient to take Phentermine/topiramate to
avoid insomnia? - correct answer given before 1600
What are some high-risk patient conditions that we should use
Phentermine/topiramate with caution? - correct answer hx drug abuse,
glaucoma, pregnant, HTN, hyperthyroidism
Phentermine/topiramate adverse effects - correct answer insomnia,
nervousness, anxiety, depression, blurred vision
,NR 566
Which of the following would be a contraindication to prescribing
phentermine/topiramate? Select all that apply. - correct answer A)
Glaucoma
B) Hypothyroidism
C) Hypertension
D) Hyperthyroidism
E) Vitamin D Deficiency
F) A, B, E
ANSWER: A,C,D
Orlistat is a lipase inhibitor that acts on the _________ and reduces
absorption of fat by 30%. - correct answer GI tract
Take multivitamin ___hours before/after to supplement fat-soluble
vitamins that may not be absorbed well when taking Orlistat. - correct
answer 2
Orlistat is OTC as 60 mg TID with meals. Not approved in children
<____. - correct answer 12
Orlistat results in the least amount of weight loss of all. How much? -
correct answer 2-3% body weight (7 lbs in year)
, NR 566
Orlistat adverse effects - correct answer Fecal incontinence, oily rectal
leakage, flatus, abdominal cramps. liver damage (light-colored stools,
dark urine, fatigue, jaundice, anorexia)
When is Orlistat contraindicated? - correct answer In those with
malabsorption syndrome or cholestasis
What vitamin deficiency are we concerned about when taking
Orlistat...especially if the patient is on coumadin? - correct answer Monitor
Coumadin as Vitamin K deficiency may occur and intensify effect of
Coumadin.
A patient with a BMI of 27 would be considered: - correct answer
overweight
Lorcaserin adverse effects - correct answer headache, URI, back pain,
hypoglycemia (in DM), blood dyscrasias, cognitive impairment,
psychiatric disorders, priapism, pulmonary hypertension, and valvular
heart disease
Lorcaserin MOA - correct answer Reduces waist circumference, fasting
glucose, insulin, total cholesterol, LDL, triglycerides
When is Lorcaserin contraindicated? - correct answer CrCl <30
