PEDS HESI Practice Test 2026/2027 – 60+ Questions & Answers | Growth & Development, Cardiac, Respiratory, GI, Endocrine, Medications & Pediatric Nursing

This comprehensive PEDS HESI Practice Test 2026/2027 contains 60+ exam-style pediatric nursing questions with answers across 42 pages, providing targeted review of pediatric assessment, growth and development, age-appropriate communication, medication administration, respiratory and cardiac disorders, gastrointestinal conditions, endocrine problems, hematology, musculoskeletal care, immunizations, safety, emergency nursing, and family-centered care. The questions use clinical scenarios and priority-based decision making to help nursing students practice selecting appropriate assessments, interventions, teaching strategies, and responses for infants, toddlers, preschoolers, school-age children, and adolescents. A major component focuses on pediatric growth, development, communication, and psychosocial care. Questions address expected toddler and preschool behaviors, possessiveness, temper tantrums, initiative, language development, separation and hospitalization, adolescent body image, social interaction, age-appropriate play, discipline, and therapeutic communication. Students practice recognizing developmental milestones and selecting approaches such as dolls and drawing to communicate effectively with younger children. The pediatric cardiovascular material includes Tetralogy of Fallot, ventricular septal defect, patent ductus arteriosus, congestive heart failure, cardiac catheterization, and digoxin therapy. Clinical scenarios require recognition of findings such as clubbing, tachypnea, feeding difficulties, and abnormal apical heart rates, while also testing preprocedure preparation, oxygen management, nutritional intake, and family education for children with congenital heart disease. Respiratory nursing is represented through asthma, pneumonia, cystic fibrosis, oxygen therapy, respiratory assessment, and secretion management. Questions address intercostal retractions, theophylline levels, oxygen mist tents, availability of suction equipment, respiratory treatments for cystic fibrosis, aerosol therapy, postural drainage, and steatorrhea associated with cystic fibrosis. The guide repeatedly emphasizes assessment and prioritization when respiratory compromise is possible. The document provides substantial practice in gastrointestinal and congenital disorders, including pyloric stenosis, gastroesophageal reflux, celiac disease, Hirschsprung disease, esophageal atresia, cleft lip and cleft palate repair, vomiting, diarrhea, dehydration, and nutritional management. Students review manifestations such as projectile vomiting, choking and cyanosis, ribbon-like stools, feeding difficulties, and dietary choices while also considering postoperative protection of surgical sites and appropriate use of restraints. The endocrine and metabolic questions address hypothyroidism, hypopituitarism and growth hormone therapy, SIADH, hyperthyroidism, and childhood diabetes. The practice test includes cessation of previously normal growth as an early finding discussed for hypothyroidism, polyuria and polydipsia in relation to growth hormone therapy, neurological assessment with SIADH, manifestations associated with hyperthyroidism, and developmentally appropriate participation in diabetes management. Medication safety and pharmacology receive dedicated attention. Students review digoxin, theophylline, nystatin, tetracyclines, growth hormone, liquid antibiotics, liquid iron preparations, IV fluids containing potassium, and pediatric dosage calculations. The questions emphasize safe administration techniques, adverse effects, contraindications, parent education, laboratory assessment, accurate liquid measurement, topical absorption in infants, and the use of height, weight, body surface area, and nomograms when calculating pediatric medication doses. The guide also covers hematologic, oncologic, and immune-related nursing care, including sickle cell disease and sequestration crisis, hemophilia A, chemotherapy-associated neutropenia, Wilms tumor, and blood transfusion reactions. Priority interventions include maintaining hydration in sickle cell disease, applying pressure and ice for bleeding in hemophilia, recognizing infection risk with neutropenia, avoiding abdominal palpation with Wilms tumor, and stopping a transfusion when symptoms such as chills, headache, and nausea develop. Musculoskeletal, dermatologic, and injury-related content includes scoliosis surgery, fractures and cast care, Russell's traction, juvenile rheumatoid arthritis, eczema, burns, lacerations, and neurovascular assessment. Students practice identifying compromised circulation, protecting surgical sites, selecting developmentally appropriate pain-assessment methods, preventing scratching and excoriation, assessing burn patients according to priorities, and recognizing differences in estimating pediatric burn surface area. Preventive pediatric care is reinforced through questions concerning MMR and influenza vaccination, tetanus boosters, poisoning prevention, well-child assessment, fontanels, vital signs, otoscopic examination, nutrition, and medication safety. The material asks students to select safe home-care instructions and recognize findings that require additional assessment or intervention. The later questions place additional emphasis on priority setting and emergency pediatric nursing. Scenarios involve severe hypertension with acute glomerulonephritis, hypotension and polyuria, accidental vitamin ingestion, burn-related airway assessment, neurovascular changes with traction, blood transfusion reactions, and other situations requiring identification of the nurse's first or highest-priority action. Family-centered nursing concepts appear throughout the practice test. Questions address parental teaching for diabetes, cystic fibrosis, gastroesophageal reflux, hemophilia, sickle cell disease, medication administration, accidental poisoning prevention, and hospitalization. The document also examines how siblings and parents can remain involved when a child requires repeated hospitalization, reinforcing the importance of communication and family participation in pediatric care. Relevant Students This document is particularly relevant for Pediatric HESI exam candidates, nursing students taking pediatric or child-health courses, RN students, BSN students, ADN students, practical nursing students, pediatric nursing students, nursing school exit-exam candidates, clinical nursing students, and learners preparing for pediatric nursing examinations. It is especially useful for students who need scenario-based practice in pediatric assessment, growth and development, prioritization, congenital disorders, respiratory and cardiac care, GI disorders, medication safety, emergency care, patient education, and family-centered nursing. 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