PHARMACOLGY (POST RN 1st SEMESTER) 2024
1. Pharmacokinetics is:
a. The study of biological and therapeutic effects of drugs
b. The study of absorption, distribution, metabolism and excretion of drugs
c. The study of mechanisms of drug action
d. The study of methods of new drug development
2. What does “pharmacokinetics” include?
a. Complications of drug therapy
b. Drug biotransformation in the organism
c. Influence of drugs on metabolism processes
d. Influence of drugs on genes
3. The branch of pharmacology which deal the dosage of drugs ___________ .
a. Pharmacy
b. Psology
c. Chemotherapy
d. A & B both
4. What does the term “bioavailability” mean?
a. Plasma protein binding degree of substance
b. Permeability through the brain-blood barrier
c. Fraction of an uncharged drug reaching the systemic circulation following any route
administration
d. Amount of a substance in urine relative to the initial doze
5. Pick out the appropriate alimentary route of administration when passage of drugs through liver
is minimized:
a. Oral
b. Transdermal
c. Rectal
d. Intraduodenal
6. Which route of drug administration is most likely to lead to the first-pass effect?
a. Sublingual
b. Oral
c. Intravenous
d. Intramuscular
7. All of the following antibiotics are macrolides, Except
a. Erythromycin
b. Clarithromycin
c. Azithromycin
, d. Ceftriaxone
8. All of the following antibiotics inhibit protein synthesis in bacteria cell ,EXCEPT
a. Macrolides
b. Aminoglycosides
c. Tetracycline
d. Penicillin
9. Those medicines for which the physician prescription is not required called __
a. OTC
b. Norcotics
c. Opoids
d. All of these
10. ____________ means when the combination of drugs increase the effect.
a. Antagonisms
b. Synergisms
c. Teratogenic
d. Agonist
11. A drug that binds to a cell receptor and causes a response is called an:
a. Agonist
b. Antagonist
c. Receptor blocker
d. none of these
12. Most drugs and metabolites are excreted by
a. The kidneys
b. The bile
c. The lungs
d. Perspiration, saliva and tears
13. The duration of action of a drug is dependent of its
a. Plasma and tissue binding
b. Metabolism
c. Tubular filtration and secretion
d. All the above
14. Oswald Schmiedeberg is known as
a. Father of Medicine
b. Father of Pharmacognosy
c. Father of Polypharmacy
d. Father of Pharmacology
15. Factor which can affect the absorption of drug is
a. Dissolution rate
b. Particle Size
c. Lipid Solubility
d. All the above
16. Teratogenicity is
1. Pharmacokinetics is:
a. The study of biological and therapeutic effects of drugs
b. The study of absorption, distribution, metabolism and excretion of drugs
c. The study of mechanisms of drug action
d. The study of methods of new drug development
2. What does “pharmacokinetics” include?
a. Complications of drug therapy
b. Drug biotransformation in the organism
c. Influence of drugs on metabolism processes
d. Influence of drugs on genes
3. The branch of pharmacology which deal the dosage of drugs ___________ .
a. Pharmacy
b. Psology
c. Chemotherapy
d. A & B both
4. What does the term “bioavailability” mean?
a. Plasma protein binding degree of substance
b. Permeability through the brain-blood barrier
c. Fraction of an uncharged drug reaching the systemic circulation following any route
administration
d. Amount of a substance in urine relative to the initial doze
5. Pick out the appropriate alimentary route of administration when passage of drugs through liver
is minimized:
a. Oral
b. Transdermal
c. Rectal
d. Intraduodenal
6. Which route of drug administration is most likely to lead to the first-pass effect?
a. Sublingual
b. Oral
c. Intravenous
d. Intramuscular
7. All of the following antibiotics are macrolides, Except
a. Erythromycin
b. Clarithromycin
c. Azithromycin
, d. Ceftriaxone
8. All of the following antibiotics inhibit protein synthesis in bacteria cell ,EXCEPT
a. Macrolides
b. Aminoglycosides
c. Tetracycline
d. Penicillin
9. Those medicines for which the physician prescription is not required called __
a. OTC
b. Norcotics
c. Opoids
d. All of these
10. ____________ means when the combination of drugs increase the effect.
a. Antagonisms
b. Synergisms
c. Teratogenic
d. Agonist
11. A drug that binds to a cell receptor and causes a response is called an:
a. Agonist
b. Antagonist
c. Receptor blocker
d. none of these
12. Most drugs and metabolites are excreted by
a. The kidneys
b. The bile
c. The lungs
d. Perspiration, saliva and tears
13. The duration of action of a drug is dependent of its
a. Plasma and tissue binding
b. Metabolism
c. Tubular filtration and secretion
d. All the above
14. Oswald Schmiedeberg is known as
a. Father of Medicine
b. Father of Pharmacognosy
c. Father of Polypharmacy
d. Father of Pharmacology
15. Factor which can affect the absorption of drug is
a. Dissolution rate
b. Particle Size
c. Lipid Solubility
d. All the above
16. Teratogenicity is
