NU 661 MIDTERM EXAM PRIMARY CARE CHILDBEARING WOMAN REGIS Actual Exam 2026/2027 – Complete 200 Exam- Questions | 100% Verified Answers – Pass Guaranteed – Already Graded A+

NU 661 MIDTERM EXAM PRIMARY
CARE CHILDBEARING WOMAN REGIS
Actual Exam 2026/2027 – Complete
200 Exam- Questions | 100% Verified
Answers – Pass Guaranteed – Already
Graded A+


SECTION 11: PRENATAL GENETICS & SCREENING (Continued)

56. A 35-year-old G1P0 at 12 weeks gestation asks about
options for prenatal genetic testing. What is the most
appropriate initial response regarding cell-free DNA testing?

 A) It is diagnostic for chromosomal abnormalities
 B) It is a screening test with high sensitivity for trisomy 21
 C) It is only available after 20 weeks
 D) It requires an invasive procedure

Correct Answer: B) It is a screening test with high sensitivity
for trisomy 21

Rationale: Cell-free DNA testing (NIPT) is a highly sensitive
screening test for trisomy 21, 18, and 13, but it remains a
screening test, not diagnostic. It can be performed as early as 10

, weeks gestation. Positive results require confirmation with
diagnostic testing (CVS or amniocentesis).




57. A patient at 16 weeks gestation has a Quad Screen
showing elevated alpha-fetoprotein (AFP). What is the most
likely concern?

 A) Trisomy 21
 B) Neural tube defect
 C) Trisomy 18
 D) Gestational diabetes

Correct Answer: B) Neural tube defect

Rationale: Elevated AFP is associated with open neural tube
defects (spina bifida, anencephaly) and abdominal wall defects
(omphalocele, gastroschisis). Low AFP is associated with trisomy
21. Further evaluation with ultrasound is indicated.




58. What is the primary purpose of chorionic villus sampling
(CVS)?

 A) To assess fetal lung maturity
 B) To diagnose chromosomal abnormalities in the first trimester
 C) To evaluate amniotic fluid volume
 D) To determine fetal sex only

, Correct Answer: B) To diagnose chromosomal abnormalities
in the first trimester

Rationale: CVS is performed between 10-13 weeks to diagnose
chromosomal abnormalities. It provides earlier results than
amniocentesis but carries a slightly higher risk of miscarriage
(about 1 in 300-500 procedures).




59. What percentage of neural tube defects can be prevented
with adequate folic acid supplementation before conception?

 A) 30-40%
 B) 50-70%
 C) 70-80%
 D) 90-100%

Correct Answer: B) 50-70%

Rationale: Adequate folic acid supplementation (400-800 mcg
daily) before conception and during early pregnancy can prevent
50-70% of neural tube defects. This is why all women of
childbearing age are advised to take folic acid.




60. Which of the following is NOT part of the Quad Screen?

 A) Alpha-fetoprotein (AFP)
 B) Human chorionic gonadotropin (hCG)
 C) Estriol

,  D) Progesterone

Correct Answer: D) Progesterone

Rationale: The Quad Screen measures four markers: AFP, hCG,
estriol, and inhibin-A. Progesterone is not part of this screening
test.




61. A patient with a family history of cystic fibrosis asks about
carrier screening. What is the most appropriate response?

 A) Screening is only recommended if both parents are Caucasian
 B) Carrier screening should be offered to all women of
reproductive age
 C) Screening is not recommended until the third trimester
 D) Only the father needs to be screened

Correct Answer: B) Carrier screening should be offered to all
women of reproductive age

Rationale: ACOG recommends offering cystic fibrosis carrier
screening to all women who are considering pregnancy or are
currently pregnant. If the woman is found to be a carrier, the
partner should be offered screening.




62. Spinal muscular atrophy (SMA) carrier screening is
recommended for: