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LPN/LVN Nurse Refresher Comprehensive Exam 2026 | LPN-NR-CE | 100 Advanced Practice Questions & Answers with Detailed Rationales | Complete Exam Prep & Study Guide

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Prepare for the LPN/LVN Nurse Refresher Comprehensive Exam — Code: LPN-NR-CE with this comprehensive 2026 advanced practice exam and study guide. This resource contains 100 practice questions with correct answers and detailed rationales, designed to support LPN/LVN learners reviewing essential practical nursing knowledge, clinical skills, patient care, safety, and professional nursing concepts. The practice questions are structured to encourage clinical reasoning and application of nursing knowledge to realistic patient-care situations. Detailed rationales explain the reasoning behind each answer, helping learners identify knowledge gaps and strengthen their exam preparation. Key Features 100 advanced LPN/LVN nurse refresher practice questions Correct answers for every question Detailed rationales for comprehensive review Practical nursing-focused exam preparation Clinical scenario-based questions Fundamentals of nursing Patient assessment and monitoring Medication administration and safety Dosage calculation concepts Infection prevention and control Vital signs and patient monitoring Basic medical-surgical nursing Chronic and acute patient care Emergency nursing concepts Documentation and communication Patient safety and risk reduction Health education and patient-centered care Professional nursing responsibilities Comprehensive 2026 refresher preparation

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LPN/LVN Nurse Refresher
Comprehensive Exam — Code: LPN-NR-
CE | 100-Question Advanced Practice
Exam 2026 | Questions & Answers with
Detailed Rationales | Complete Exam
Prep & Study Guide


1.

A client with heart failure suddenly develops severe dyspnea, pink frothy sputum,
and bilateral crackles. Which action should the LPN/LVN take first?

A. Encourage oral fluids
B. Place the client in high-Fowler's position
C. Obtain the client's daily weight
D. Administer a prescribed oral diuretic

Answer: B. Place the client in high-Fowler's position

Rationale: High-Fowler's positioning improves lung expansion and decreases
venous return, helping reduce pulmonary congestion while additional
interventions are initiated.

,2.

A postoperative client becomes restless and confused. The respiratory rate is
30/min, oxygen saturation is 86% on room air, and the skin is cool. What is the
priority action?

A. Administer an opioid analgesic
B. Reassure the client
C. Apply supplemental oxygen according to protocol
D. Document the findings

Answer: C. Apply supplemental oxygen according to protocol

Rationale: Acute hypoxemia can initially manifest as restlessness and confusion.
Oxygenation is the immediate priority while the cause is assessed and further
treatment is initiated.

3.

A client receiving IV potassium chloride reports burning at the IV site. The site
appears swollen and cool. What should the nurse do first?

A. Slow the infusion
B. Apply a warm compress
C. Stop the infusion
D. Flush the catheter vigorously

Answer: C. Stop the infusion

Rationale: Pain, swelling, and coolness suggest infiltration or extravasation.
Potassium is irritating to tissue, so the infusion should be stopped immediately
and the IV assessed according to facility protocol.

4.

A client with diabetes is awake, diaphoretic, shaky, and has a blood glucose level
of 52 mg/dL. What is the best initial intervention?

,A. Administer regular insulin
B. Give 15 g of rapid-acting carbohydrate
C. Give a high-protein meal
D. Restrict oral intake

Answer: B. Give 15 g of rapid-acting carbohydrate

Rationale: A conscious client who can swallow safely should receive
approximately 15 g of fast-acting carbohydrate, followed by reassessment of
glucose according to the 15-15 approach.

5.

A client receiving warfarin has an INR of 5.8 and reports new gum bleeding. Which
action is most appropriate?

A. Administer the next scheduled dose
B. Encourage foods high in vitamin K immediately
C. Hold the medication and notify the provider
D. Administer aspirin

Answer: C. Hold the medication and notify the provider

Rationale: An elevated INR accompanied by active bleeding indicates excessive
anticoagulation and requires prompt provider notification and further
management.

6.

A client with COPD is receiving oxygen. Which finding requires the most
immediate attention?

A. Oxygen saturation of 90%
B. Productive cough with clear sputum
C. Increasing somnolence and shallow respirations
D. Respiratory rate of 20/min

Answer: C. Increasing somnolence and shallow respirations

, Rationale: Increasing somnolence with hypoventilation may indicate worsening
carbon dioxide retention and respiratory failure.

7.

A client with suspected stroke suddenly develops facial drooping and right-sided
weakness. Which information is most important to determine immediately?

A. Last bowel movement
B. Time the client was last known well
C. Current dietary preference
D. Previous influenza vaccination

Answer: B. Time the client was last known well

Rationale: The exact last-known-well time is critical because eligibility for time-
sensitive stroke therapies depends on the onset or last-known-normal time.

8.

A client with chronic kidney disease has a potassium level of 6.7 mEq/L. Which
finding is the greatest concern?

A. Muscle weakness
B. Peaked T waves on ECG
C. Mild nausea
D. Increased thirst

Answer: B. Peaked T waves on ECG

Rationale: Severe hyperkalemia can cause life-threatening cardiac
dysrhythmias. ECG changes require immediate intervention and provider
notification.

9.

A client receiving a blood transfusion develops chills, fever, and low back pain 15
minutes after the transfusion begins. What should the nurse do first?

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