NR507- Midterm Advanced Patho- cardiac, pulmonary, hematology, renal
NR507- Midterm Advanced Patho- cardiac, pulmonary, hematology, renal
Study online at https://quizlet.com/_6vx0kv
1. Hematopoiesis blood cell formation
Fetus- liver and spleen
Adult- bone marrow
2. Anemia A condition in which the blood is deficient in red blood cells, in hemoglobin, or in
total volume.
3. Erythropoiesis formation of red blood cells
In kidney in response to hypoxia
4. macrocytic nor- Large RBC's, normal hemoglobin
mochromic ane- Folic acid or Vitamin B12 deficiency
mia
5. microcytic small, abnormally shaped erythrocytes that are not able to carry normal hemoglo-
hypochromic bin
anemia Thalassemia- mediterranean
6. normocytic nor- Characterized by red cells that are relatively normal in size and normal hemoglobin
mochromic ane- Aplastic, hemorrhagic, hemolytic, sickle cell
mia
7. iron deficiency anemia resulting when there is not enough iron to build hemoglobin for red blood
anemia cells
Affects children, poverty, child bearing age
8. Erythrocytes red blood cells
Most abundant cell in the body
Responsible for tissue oxygenation
Mitotic division- 100-120 days
9. sickle cell anemia A genetic disorder in which erythroctyes take on an abnormal curved or "sickle"
shape (Hb-s)
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, NR507- Midterm Advanced Patho- cardiac, pulmonary, hematology, renal
NR507- Midterm Advanced Patho- cardiac, pulmonary, hematology, renal
Study online at https://quizlet.com/_6vx0kv
10. Thalassemia Inherited defect in the ability to produce hemoglobin, usually seen in persons of
Mediterranean background.
11. pernicious ane- Lack of mature erythrocytes caused by inability to absorb vitamin B12 into the
mia bloodstream
12. hemolytic ane- Characterized by an inadequate number of circulating red blood cells due to the
mia premature destruction of red blood cells by the spleen
Pancytopenia- reduction in all 3 types of blood cells (RBC, WBC, Plt)
13. Erythropoietin Hormone secreted by the kidney to stimulate the production of red blood cells by
(EPO) bone marrow
In response to hypoxia
In the fetus the liver produces this
14. Hemoglobin Iron-containing protein in red blood cells that carries oxygen for delivery to cells
4 molecules of O2
Made of polypeptide, heme, iron
15. anemia due to Iron def anemia is major cause after this
gastrectomy Removal of stomach often leads to marked decrease in production of gastric acid.
This acid is necessary to convert dietary iron to a form that is more readily absorbed
by the duodenum
16. hemolytic ane- Sickle cell disease, ABO or Rh incompatibility, drug induced
mia causes
17. Role of Innate:
macrophages 1. Phagocytosis
PRR or opsonization w/ complement
2. Secrete Cytokines: Recruit more cells, inflammation, fever, etc.
Adaptive:
2 of 11
NR507- Midterm Advanced Patho- cardiac, pulmonary, hematology, renal
Study online at https://quizlet.com/_6vx0kv
1. Hematopoiesis blood cell formation
Fetus- liver and spleen
Adult- bone marrow
2. Anemia A condition in which the blood is deficient in red blood cells, in hemoglobin, or in
total volume.
3. Erythropoiesis formation of red blood cells
In kidney in response to hypoxia
4. macrocytic nor- Large RBC's, normal hemoglobin
mochromic ane- Folic acid or Vitamin B12 deficiency
mia
5. microcytic small, abnormally shaped erythrocytes that are not able to carry normal hemoglo-
hypochromic bin
anemia Thalassemia- mediterranean
6. normocytic nor- Characterized by red cells that are relatively normal in size and normal hemoglobin
mochromic ane- Aplastic, hemorrhagic, hemolytic, sickle cell
mia
7. iron deficiency anemia resulting when there is not enough iron to build hemoglobin for red blood
anemia cells
Affects children, poverty, child bearing age
8. Erythrocytes red blood cells
Most abundant cell in the body
Responsible for tissue oxygenation
Mitotic division- 100-120 days
9. sickle cell anemia A genetic disorder in which erythroctyes take on an abnormal curved or "sickle"
shape (Hb-s)
1 of 11
, NR507- Midterm Advanced Patho- cardiac, pulmonary, hematology, renal
NR507- Midterm Advanced Patho- cardiac, pulmonary, hematology, renal
Study online at https://quizlet.com/_6vx0kv
10. Thalassemia Inherited defect in the ability to produce hemoglobin, usually seen in persons of
Mediterranean background.
11. pernicious ane- Lack of mature erythrocytes caused by inability to absorb vitamin B12 into the
mia bloodstream
12. hemolytic ane- Characterized by an inadequate number of circulating red blood cells due to the
mia premature destruction of red blood cells by the spleen
Pancytopenia- reduction in all 3 types of blood cells (RBC, WBC, Plt)
13. Erythropoietin Hormone secreted by the kidney to stimulate the production of red blood cells by
(EPO) bone marrow
In response to hypoxia
In the fetus the liver produces this
14. Hemoglobin Iron-containing protein in red blood cells that carries oxygen for delivery to cells
4 molecules of O2
Made of polypeptide, heme, iron
15. anemia due to Iron def anemia is major cause after this
gastrectomy Removal of stomach often leads to marked decrease in production of gastric acid.
This acid is necessary to convert dietary iron to a form that is more readily absorbed
by the duodenum
16. hemolytic ane- Sickle cell disease, ABO or Rh incompatibility, drug induced
mia causes
17. Role of Innate:
macrophages 1. Phagocytosis
PRR or opsonization w/ complement
2. Secrete Cytokines: Recruit more cells, inflammation, fever, etc.
Adaptive:
2 of 11
