WSCC Pharmacology Exam 1 Latest Update
Drug - ANSWER Any chemical substance that, when administered,
produces a change in function
Pharmacology - ANSWER The study of the effects of chemical substances
on living tissues. More specifically, it is the study of drugs, their sources,
their nature, and their properties: and more importantly for our purposes, it
is the study of body's reaction to drugs
Clinical Pharmacology - ANSWER the study of drugs used to treat,
diagnose, or prevent a disease
1914 Harrison Narcotic Act - ANSWER Regulates and taxes the
production, importation, and distribution of opiates and cocoa products
1938 Food, Drug, and Cosmetic Act - ANSWER Empowered the FDA to
monitor and regulate the manufacturer of drugs
1970 Controlled Substance Act - ANSWER Classify drugs according to
abuse potential
Teratogenic - ANSWER Turns babies into monsters (Loss of limbs)
Black Box - ANSWER Side effects that show up after the drug is put on the
market
Tuskegee - ANSWER 1932 study about syphilis, penicillin came out & they
didn't give the medication to the patients in the trial, and some people died
from it
, What is the name of the governing body who decides the laws regarding
drug administration in Tennessee? - ANSWER The Tennessee State Board
of Nursing
Off-label uses - ANSWER A medication used for something that it has not
been approved for
Pharmaceutic phase of drug action - ANSWER -Disintegration (Chew it)
and Dissolution (Happens in stomach)
-Needed for PO meds only
-May be enhanced by excipients
-May be altered by gastric pH
Why should the nurse not crush enteric coated pills? - ANSWER because
they get absorbed to quickly
Why should the nurse not crush sustained-release capsules? - ANSWER
Because the patient would get it all at once instead of systematically
Pharmacokinetic Processes - ANSWER 2nd phase of drug action
absorption, distribution, metabolism, and excretion
Absorption - ANSWER -Can be passive or active
-Passive doesn't need energy (Diffusion and Facilitated diffusion)
-Active (Water soluble needs energy)
-Pinocytosis
Hepatic First-Pass Effect - ANSWER Drugs taken orally are "routed" to the
liver via the portal vein
All meds taken orally will have a percentage of this effect.
Some of the medicine will go to work, while the other part of the medicine
will be metabolized out of the body.
If the patient is given 5mg of IV morphine, the patient will be given a bigger
dose when given PO morphine
Bio-availability - ANSWER A subcategory of absorption
Always less than a 100% for drugs given PO
May be 100% for drugs given IV
Drug - ANSWER Any chemical substance that, when administered,
produces a change in function
Pharmacology - ANSWER The study of the effects of chemical substances
on living tissues. More specifically, it is the study of drugs, their sources,
their nature, and their properties: and more importantly for our purposes, it
is the study of body's reaction to drugs
Clinical Pharmacology - ANSWER the study of drugs used to treat,
diagnose, or prevent a disease
1914 Harrison Narcotic Act - ANSWER Regulates and taxes the
production, importation, and distribution of opiates and cocoa products
1938 Food, Drug, and Cosmetic Act - ANSWER Empowered the FDA to
monitor and regulate the manufacturer of drugs
1970 Controlled Substance Act - ANSWER Classify drugs according to
abuse potential
Teratogenic - ANSWER Turns babies into monsters (Loss of limbs)
Black Box - ANSWER Side effects that show up after the drug is put on the
market
Tuskegee - ANSWER 1932 study about syphilis, penicillin came out & they
didn't give the medication to the patients in the trial, and some people died
from it
, What is the name of the governing body who decides the laws regarding
drug administration in Tennessee? - ANSWER The Tennessee State Board
of Nursing
Off-label uses - ANSWER A medication used for something that it has not
been approved for
Pharmaceutic phase of drug action - ANSWER -Disintegration (Chew it)
and Dissolution (Happens in stomach)
-Needed for PO meds only
-May be enhanced by excipients
-May be altered by gastric pH
Why should the nurse not crush enteric coated pills? - ANSWER because
they get absorbed to quickly
Why should the nurse not crush sustained-release capsules? - ANSWER
Because the patient would get it all at once instead of systematically
Pharmacokinetic Processes - ANSWER 2nd phase of drug action
absorption, distribution, metabolism, and excretion
Absorption - ANSWER -Can be passive or active
-Passive doesn't need energy (Diffusion and Facilitated diffusion)
-Active (Water soluble needs energy)
-Pinocytosis
Hepatic First-Pass Effect - ANSWER Drugs taken orally are "routed" to the
liver via the portal vein
All meds taken orally will have a percentage of this effect.
Some of the medicine will go to work, while the other part of the medicine
will be metabolized out of the body.
If the patient is given 5mg of IV morphine, the patient will be given a bigger
dose when given PO morphine
Bio-availability - ANSWER A subcategory of absorption
Always less than a 100% for drugs given PO
May be 100% for drugs given IV
