NUR 546 Midterm Exam Review: Psychopharmacology PMHNP Study Guide

Chamberlain University

NUR 546 Psychopharmacology
for the Psychiatric-Mental
Health Nurse Practitioner
NUR 546 Midterm
Course Title and Number: NUR 546 Psychopharmacology for
the Psychiatric-Mental Health Nurse Practitioner

Exam Title: NUR 546 Midterm

Exam Date: MIDTERM Exam 2024- 2025

Instructor: [Insert Instructor’s Name]

Student Name: [Insert Student’s Name]

Student ID: [Insert Student ID]


Midterm Examination
180 minutes

Instructions:
1. Read each question carefully.
2. Answer all questions.
3. Use the provided answer sheet to mark your
responses.
4. Ensure all answers are final before submitting the
exam.

Good Luck!

,NUR 546 Psychopharmacology for the
Psychiatric-Mental Health Nurse
Practitioner PMHNP 2024-2025 NUR
546 Midterm Actual Exam Review
Questions and Answers | 100% Pass |
Grades A+| Guaranteed Success
The amygdala hypothetically plays a central role in the
_______________. Cortico-striato-thalamo-cortical (CSTC)
circuits are thought to play a key role in mediating the
symptom of __________. - Answer>> fear response,
worry

________,_________,_________,________ are all key
modulators of the hypothetical fear and worry circuits -
Answer>> Serotonin, norepinephrine, alpha-2 delta
ligands and GABA

Why is trazodone not used as a front-line
antidepressant - Answer>> Its antidepressant that has
a secondary effect of blocking histamine and
adrenergic receptors
-causes sedation and somnolence and as a result
*often used as an adjunct in therapy when a depressed
patient has difficulty sleeping

effect on neurotransmitters and side effects: Selective
Serotonin Reuptake Inhibitors (SSRIs) - Answer>>
Inhibits the reuptake of serotonin, which can cause
nausea, agitation, headache, and sexual dysfunction

effect on neurotransmitters and side effects: Serotonin
and Norepinephrine Reuptake Inhibitors (SNRIs) -

,Answer>> Inhibits the reuptake of serotonin and
norepinephrine, which can cause nausea, sweating,
insomnia, tremors, sexual dysfunction

effect on neurotransmitters and side effects: Tricyclic
Antidepressants - Answer>> -Inhibits the reuptake of
serotonin and norepinephrine, which can cause sexual
dysfunction
-Blocks norepinephrine receptors, which can cause
hypotension and tachycardia
-Blocks histamine receptors, which can cause sedation
and weight gain
-Blocks acetylcholine receptors, which can cause dry
mouth, constipation, blurred vision, and urinary
retention

effect on neurotransmitters and side effects:
Monoamine Oxidase Inhibitors (MAOIs) - Answer>>
Increases norepinephrine and serotonin by inhibiting
the enzyme that inactivates it, which can cause
sedation, dizziness, sexual dysfunction, and
hypertensive crisis

effect on neurotransmitters and side effects:
Benzodiazepines - Answer>> Increases the receptor
affinity for GABA, which can cause dependence and
confusion

effect on neurotransmitters and side effects: Bupropion
- Answer>> Inhibits the reuptake of norepinephrine
and dopamine, which can cause insomnia, dry mouth,
tremors, and seizures

antagonist - Answer>> causes a conformational
change that stabilizes the receptor in the baseline state
and thus is "silent."
-blocks the action of a neurotransmitter

, agonists - Answer>> fully stimulate G-protein-linked
receptors

partial agonists - Answer>> stimulate receptors to a
lesser degree than an agonist or natural
neurotransmitter

SSRIs, SNRIs, and tricyclic antidepressants increase
________ levels.
___________ do not impact serotonin levels. - Answer>>
increase serotonin levels.
Benzodiazepines do not impact serotonin levels.

Is nicotine an inducer or an inhibitor of the CYP 1A2
enzyme? - Answer>> inducer

Nicotine is an inducer of the CYP 1A2 enzyme. Does the
PMHNP anticipate Joshua may need a higher or lower
dose of olanzapine to achieve a therapeutic response? -
Answer>> Higher
-Nicotine is an inducer of the CYP 1A2 enzyme, so it
lowers the concentration of drugs. Therefore, a higher
dose of olanzapine may be needed to control his
symptoms.

Ernesto, a 60-year-old, presents to the PMHNP with
report of having anxiety, frequent occurrences of
feeling frozen in place and like his heart is pounding out
of his chest, as well as having difficulty sleeping.
The PMHNP suspects the client has an elevated level of
which neurotransmitter? - Answer>> Norepinephrine
-responsible for the regulation of fight or flight
responses and can impact mood and sleep.

Which of the following is the best medication class for
the PMHNP to prescribe for Ernesto to address his