NR 565 ADVANCED PHARMACOLOGY FUNDAMENTALS EXAM PREP 2026 MEDICATION SAFETY AND CLINICAL DECISION MAKING GUIDE

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NR 565 ADVANCED PHARMACOLOGY FUNDAMENTALS EXAM PREP 2026 MEDICATION SAFETY AND CLINICAL DECISION MAKING GUIDE

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NR 565 ADVANCED PHARMACOLOGY FUNDAMENTALS EXAM PREP 2026 MEDICATION SAFETY AND CLINICAL DECISION MAKING GUIDE

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NR 565 ADVANCED PHARMACOLOGY
FUNDAMENTALS EXAM PREP 2026
MEDICATION SAFETY AND CLINICAL
DECISION MAKING GUIDE

◉ Xenobiotics
Answer: Substances that are foreign to the body
Synthetic chemical compounds
Medications
All can potentially adversely affect the body
*Occasionally can be transformed into toxic metabolite

◉ Cytochrome P450 (CYP450)
Answer: Xenobioitic-metabolizing enzymes
Necessary for the production of cholesterol and steroids

◉ Role of CYP450
Answer: Detoxification of chemicals
Drug metabolism

◉ CYP450: cyto

, Answer: Binds to cell membrane

◉ CYP450: chrome + p
Answer: Contains heme pigment

◉ CYP450: 450 mm
Answer: Absorbs light at 450 mm wavelength when exposed to
carbon monoxide (CO)

◉ CYP450 system is thought to be ___
Answer: Major system of enzymes responsible for phase 1
metabolism

◉ 3 possible outcomes of phase 1 metabolism
Answer: Oxidized (most common)
Reduced
Hydrolyzed

◉ Oxidation
Answer: Drug becomes completely inactive

◉ Reduction

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Study: NR 548 ADVANCED PHARMACOLOGY ASSESSMENT 2026 MEDIC
Uploaded on: August 23, 2026
Number of pages: 10
Written in: 2026/2027
Type: Exam (elaborations)
Contains: Questions & answers

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