1|Page
HESI PHARMACOLOGY EVOLVE / EVOLVE PHARMACOLOGY
HESI NEWEST 2026/2027 COMPLETE 180 QUESTIONS AND
CORRECT DETAILED ANSWERS (VERIFIED ANSWERS) |ALREADY
GRADED A+||JUST OUT!!!
A client with HIV who was recently diagnosed with tuberculosis
(TB) asks the nurse, "Why do I need to take all of these
medications for TB?" What information should the nurse
provide?
A. Antiretroviral medications decrease the efficacy of the TB
drugs.
B. Multiple drugs prevent the development of resistant
organisms.
C. Duration of the medication regimen is shortened.
D. Potential adverse drug reactions are minimized. - ANSWER-B.
Multiple drugs prevent the development of resistant organisms.
A multidrug regimen is prescribed for a client with HIV and TB
to prevent the development of resistance of the tubercle bacilli.
Although antitubercular medications can inhibit some
antiretrovirals, a multidrug regimen is needed to inhibit the
proliferation of the virulent tubercle bacilli. The duration of
antitubercular therapy is typically 6 to 9 months and is not
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shortened by the use of multiple medications. A client who is
receiving HIV and TB therapy is at an increased risk of adverse
reactions because of the complex medication regimens and
complications secondary to immunosuppression.
A 67-year-old client is discharged from the hospital with a
prescription for digoxin, 0.25 mg daily. Which instruction should
the nurse include in this client's discharge teaching plan?
A. Take the medication in the morning before rising.
B. Take and record radial pulse rate daily.
C. Expect some vision changes caused by the medication.
D. Increase intake of foods rich in vitamin K. - ANSWER-B. Take
and record radial pulse rate daily.
Monitoring pulse rate is very important when taking digoxin.
The client should be further instructed to report pulse rates <60
or >110 beats/min and to withhold the dosage until consulting
with the health care provider in such a case. Options A and D
are not necessary. Option C is an indication of drug toxicity, and
the client should be instructed to report this immediately.
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A client is prescribed a cholinesterase inhibitor, and a family
member asks the nurse how this medication works. Which
pharmacophysiologic explanation should the nurse use to
describe this class of drug?
A. Promotes excretion of neurotoxins.
B. Slows nerve cell degeneration.
C. Improves nerve impulse transmission.
D. Stimulates nerve cell regeneration. - ANSWER-C. Improves
nerve impulse transmission.
Cholinesterase inhibitors work to increase the availability of
acetylcholine at cholinergic synapses, which aids in neuronal
transmission and assists in memory formation. Basing an
explanation on this concept, option C should provide an
accurate explanation that the family can understand. Options A,
B, and D are incorrect.
In developing a nursing care plan for a 9-month-old infant with
cystic fibrosis, the nurse writes a nursing diagnosis of alteration
in nutrition: less than body requirements, related to inadequate
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digestion of nutrients. Which intervention would best meet this
child's needs?
A. Give aluminum hydroxide and magnesium hydroxide after
meals.
B. Give pancrelipase capsule mixed with applesauce before
each meal.
C. Administer cholestyramine resin before each meal and at
bedtime.
D. Administer omeprazole for gastroesophageal reflux. -
ANSWER-B. Give pancrelipase capsule mixed with applesauce
before each meal.
Pancreatic enzyme replacement with pancrelipase is a major
component of cystic fibrosis nutritional management.
Aluminum hydroxide and magnesium hydroxide may be given
before meals with enzymes to reduce gastric acidity and
prevent enzyme destruction but are ineffective when used
alone to promote enzyme replacement. Options C and D are
used to treat steatorrhea in cystic fibrosis.
HESI PHARMACOLOGY EVOLVE / EVOLVE PHARMACOLOGY
HESI NEWEST 2026/2027 COMPLETE 180 QUESTIONS AND
CORRECT DETAILED ANSWERS (VERIFIED ANSWERS) |ALREADY
GRADED A+||JUST OUT!!!
A client with HIV who was recently diagnosed with tuberculosis
(TB) asks the nurse, "Why do I need to take all of these
medications for TB?" What information should the nurse
provide?
A. Antiretroviral medications decrease the efficacy of the TB
drugs.
B. Multiple drugs prevent the development of resistant
organisms.
C. Duration of the medication regimen is shortened.
D. Potential adverse drug reactions are minimized. - ANSWER-B.
Multiple drugs prevent the development of resistant organisms.
A multidrug regimen is prescribed for a client with HIV and TB
to prevent the development of resistance of the tubercle bacilli.
Although antitubercular medications can inhibit some
antiretrovirals, a multidrug regimen is needed to inhibit the
proliferation of the virulent tubercle bacilli. The duration of
antitubercular therapy is typically 6 to 9 months and is not
,2|Page
shortened by the use of multiple medications. A client who is
receiving HIV and TB therapy is at an increased risk of adverse
reactions because of the complex medication regimens and
complications secondary to immunosuppression.
A 67-year-old client is discharged from the hospital with a
prescription for digoxin, 0.25 mg daily. Which instruction should
the nurse include in this client's discharge teaching plan?
A. Take the medication in the morning before rising.
B. Take and record radial pulse rate daily.
C. Expect some vision changes caused by the medication.
D. Increase intake of foods rich in vitamin K. - ANSWER-B. Take
and record radial pulse rate daily.
Monitoring pulse rate is very important when taking digoxin.
The client should be further instructed to report pulse rates <60
or >110 beats/min and to withhold the dosage until consulting
with the health care provider in such a case. Options A and D
are not necessary. Option C is an indication of drug toxicity, and
the client should be instructed to report this immediately.
,3|Page
A client is prescribed a cholinesterase inhibitor, and a family
member asks the nurse how this medication works. Which
pharmacophysiologic explanation should the nurse use to
describe this class of drug?
A. Promotes excretion of neurotoxins.
B. Slows nerve cell degeneration.
C. Improves nerve impulse transmission.
D. Stimulates nerve cell regeneration. - ANSWER-C. Improves
nerve impulse transmission.
Cholinesterase inhibitors work to increase the availability of
acetylcholine at cholinergic synapses, which aids in neuronal
transmission and assists in memory formation. Basing an
explanation on this concept, option C should provide an
accurate explanation that the family can understand. Options A,
B, and D are incorrect.
In developing a nursing care plan for a 9-month-old infant with
cystic fibrosis, the nurse writes a nursing diagnosis of alteration
in nutrition: less than body requirements, related to inadequate
, 4|Page
digestion of nutrients. Which intervention would best meet this
child's needs?
A. Give aluminum hydroxide and magnesium hydroxide after
meals.
B. Give pancrelipase capsule mixed with applesauce before
each meal.
C. Administer cholestyramine resin before each meal and at
bedtime.
D. Administer omeprazole for gastroesophageal reflux. -
ANSWER-B. Give pancrelipase capsule mixed with applesauce
before each meal.
Pancreatic enzyme replacement with pancrelipase is a major
component of cystic fibrosis nutritional management.
Aluminum hydroxide and magnesium hydroxide may be given
before meals with enzymes to reduce gastric acidity and
prevent enzyme destruction but are ineffective when used
alone to promote enzyme replacement. Options C and D are
used to treat steatorrhea in cystic fibrosis.
