Hematology Questions | Questions with 100% Verified Answers
| Latest Update 2026/2027
Question: A patient comes to their PCP with pallor, fatigue, shortness of breath, and low blood pressure. What
could be the hematological differential diagnosis?
A. Hemolysis
B. thrombocytopenia
C. Anemia
D. Splenomegaly
Answer: C. Anemia
Question: In order to make a differential diagnosis of abnormalities in the blood _______, WBC, platelets, and
coagulation should be analyzed
Answer: RBC
Question: If a patient presents to their primary care physician with a social history of 36 cans of beer each day,
increased weight loss, and a vitamin B12 level of 150 pg/mL. What hematological disorder could be present in
this patient?
A. Microcytic anemia
B. Megaloblastic anemia
C. Polycythemia
D. Leukemia
Answer: B. Megaloblastic anemia
Question: A 6 year old boy presents with spoon nails, glossitis, and an abnormal craving to eat sand and dirt.
Which of the following disease states could be the cause of these symptoms?
A. Hodgkin lymphoma
B. Iron deficiency
C. Clotting factor deficiency
D. Hemolysis
Answer: B. Iron deficiency
Question: Select 2 possible causes of glossitis
A. Iron deficiency
B. Vitamin B12 deficiency
C. Thiamine
D. Folic Acid
Answer: A & B
Question: Select the answer that has the correct reference range matched with the correct lab value
A. Sodium: 50-60 mEq/L
B. Magnesium: 15-20 mEq/L
C. Albumin 3.5-5.5 g/dL
D. Alkaline phosphatase: 120-140 U/L
Answer: C. Albumin 3.5-5.5 g/dL
, Question: A patient has a mean cell hemoglobin concentration of 21% hb/cell. What are the possible causes?
A. Deficiency in Hgb synthesis
B. Spherocytosis
C. Autoimmune diseases
D. Bone marrow diseases
E. A and B
F. All of the above
Answer: E. A and B
Question: Which of the following 3 definitions are matched correctly?
A. Anemia - increase in red cell count
B. Leukocytosis - decrease in white cell count
C. Pancytopenia - decrease in all myeloid elements
D. Erythrocytosis - increase in red cell count
E. Thrombocytopenia - increase in platelet count
F. Lymphocytosis - increase in lymphocyte count
Answer: C, D, & F
Question: A bone marrow biopsy would be appropriate to determine which of the following?
A. Elevated platelet count
B. Decreased MCH
C. Increased myeloblasts
D. Anisocytosis
Answer: C. Increased myeloblasts
Question: _______ is when blood samples are smeared on a microscope slide and changes in number and shape
of cells are recognized
A. Culture and sensitivity
B. Blood culture
C. Peripheral smear
D. Hemoglobin-Hematocrit analysis
Answer: C. Peripheral smear
Question: What are the 3 important body components of hematology?
A. Secondary lymphoid tissue
B. Heart
C. Biliary system
D. Thymus
E. Gastrointestinal system
F. Bone marrow
Answer: A, D, & F
Question: Bone marrow tissue contains all of the following cells except:
A. Platelets
B. Mononuclear cells
C. Megakaryocytes
D. Fat Cells
Answer: A. Platelets
| Latest Update 2026/2027
Question: A patient comes to their PCP with pallor, fatigue, shortness of breath, and low blood pressure. What
could be the hematological differential diagnosis?
A. Hemolysis
B. thrombocytopenia
C. Anemia
D. Splenomegaly
Answer: C. Anemia
Question: In order to make a differential diagnosis of abnormalities in the blood _______, WBC, platelets, and
coagulation should be analyzed
Answer: RBC
Question: If a patient presents to their primary care physician with a social history of 36 cans of beer each day,
increased weight loss, and a vitamin B12 level of 150 pg/mL. What hematological disorder could be present in
this patient?
A. Microcytic anemia
B. Megaloblastic anemia
C. Polycythemia
D. Leukemia
Answer: B. Megaloblastic anemia
Question: A 6 year old boy presents with spoon nails, glossitis, and an abnormal craving to eat sand and dirt.
Which of the following disease states could be the cause of these symptoms?
A. Hodgkin lymphoma
B. Iron deficiency
C. Clotting factor deficiency
D. Hemolysis
Answer: B. Iron deficiency
Question: Select 2 possible causes of glossitis
A. Iron deficiency
B. Vitamin B12 deficiency
C. Thiamine
D. Folic Acid
Answer: A & B
Question: Select the answer that has the correct reference range matched with the correct lab value
A. Sodium: 50-60 mEq/L
B. Magnesium: 15-20 mEq/L
C. Albumin 3.5-5.5 g/dL
D. Alkaline phosphatase: 120-140 U/L
Answer: C. Albumin 3.5-5.5 g/dL
, Question: A patient has a mean cell hemoglobin concentration of 21% hb/cell. What are the possible causes?
A. Deficiency in Hgb synthesis
B. Spherocytosis
C. Autoimmune diseases
D. Bone marrow diseases
E. A and B
F. All of the above
Answer: E. A and B
Question: Which of the following 3 definitions are matched correctly?
A. Anemia - increase in red cell count
B. Leukocytosis - decrease in white cell count
C. Pancytopenia - decrease in all myeloid elements
D. Erythrocytosis - increase in red cell count
E. Thrombocytopenia - increase in platelet count
F. Lymphocytosis - increase in lymphocyte count
Answer: C, D, & F
Question: A bone marrow biopsy would be appropriate to determine which of the following?
A. Elevated platelet count
B. Decreased MCH
C. Increased myeloblasts
D. Anisocytosis
Answer: C. Increased myeloblasts
Question: _______ is when blood samples are smeared on a microscope slide and changes in number and shape
of cells are recognized
A. Culture and sensitivity
B. Blood culture
C. Peripheral smear
D. Hemoglobin-Hematocrit analysis
Answer: C. Peripheral smear
Question: What are the 3 important body components of hematology?
A. Secondary lymphoid tissue
B. Heart
C. Biliary system
D. Thymus
E. Gastrointestinal system
F. Bone marrow
Answer: A, D, & F
Question: Bone marrow tissue contains all of the following cells except:
A. Platelets
B. Mononuclear cells
C. Megakaryocytes
D. Fat Cells
Answer: A. Platelets
