N212 Pathophysiology Exam 2026 Actual Test
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Mr. Forbes is being prepared for open heart surgery when he suffers a myocardial infarction in
which a large part of his left ventricle has suffered lethal cell injury.
Mr. Forbes' CPK-MB and LDH1, enzymes associated with myocardial cells, are significantly
elevated. What is the best explanation for this?
a. It is a sign that necrotic myocardial cells have released their cytoplasmic contents into the
blood.
b. It is a sign of reversible fatty accumulation in the myocardial cells
c. It is a sign that the myocardial cells are undergoing hypertrophy.
d. None of the above. –
Correct Answer :A
A+ TEST BANK 1
, N212 Pathophysiology Exam
If a tissue specimen of myocardial cells were obtained for examination from Mr. Forbes, which
of the following findings would indicate irreversible cell injury?
a. cellular swelling
b. decreased ATP production
c. decreased intracellular calcium
d. dissolution of nuclear material –
Correct Answer :D
The accumulation of lactic acid that occurs with impaired energy production results from
which of the following?
a. increased intracellular glucose
b. increased anaerobic metabolism
c. decreased metabolic rate
d. increased oxidative phosphorylation –
Correct Answer :B
A mountain climber is stranded at 23,000 feet in the Swiss Alps and has lost all his equipment
and supplies in an avalanche. Subsequently, he suffers cell injury due to impaired ATP
production. The reason for the decrease in ATP is which of the following?
a. enzyme inhibition
b. uncoupling
c. hypoxia
d. none of the above –
Correct Answer :C
A+ TEST BANK 2
, N212 Pathophysiology Exam
An elderly patient develops an obstruction in his left middle cerebral artery. The brain tissue
supplied by this artery becomes hypoxic. The best explanation for this is which of the
following?
a. the obstruction results in decreased blood flow
b. the obstruction results in decreased hemoglobin in the blood
c. while blood flow stays the same, the obstruction reduces oxygen content in the blood
d. none of the above explain the reason for the hypoxia –
Correct Answer :A
Increased mobilization and delivery of free fatty acids to liver cells can result in fat
accumulation. Which of the following problems results in increased mobilization of free fatty
acids?
a. anemia
b. hepatic toxins
c. starvation
d. hypoxia –
Correct Answer :C
Generalized hypoxia results in a switch to anaerobic metabolism in cells. Anaerobic
metabolism results in which of the following?
a. decreased lactic acid inside cells
b. decreased arterial pH
c. more effective ATP production
d. increased pH inside cells –
A+ TEST BANK 3
, N212 Pathophysiology Exam
Correct Answer :B
There is a disease of the spleen, which results in an excessive destruction of RBCs. This
increase in RBC destruction can lead to which of the following?
a. hypoxia
b. hypobilirubinemia
c. an increase in platelets
d. all of the above –
Correct Answer :A
Your body has developed an increased demand for thyroid hormones. This will lead to
____________ of the thyroid gland.
a. atrophy
b. hypertrophy
c. dysplasia
d. metaplasia –
Correct Answer :B
You palpate a gangrenous leg and note the presence of crepitus. Crepitus is associated with
which of the following?
a. wet gangrene
b. dry gangrene
c. gas gangrene
d. all of the above –
A+ TEST BANK 4