,NR 293 Final Exam Pharmacology for Nursing Questions & Answers |
2026/2027 Chamberlain
1.** A nurse is reviewing pharmacology concepts. Which term describes what
the BODY does to the drug?
A) Pharmacodynamics
B) Pharmacotherapeutics
C) Pharmacokinetics
D) Pharmacognosy
**Correct Answer:** C) Pharmacokinetics
**Rationale:** Pharmacokinetics is the study of what the body does to the
drug, including absorption, distribution, metabolism, and excretion (ADME).
Pharmacodynamics is the study of what the drug does to the body.
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**2.** Which term describes what the DRUG does to the body?
A) Pharmacokinetics
B) Pharmacodynamics
C) Pharmacotherapeutics
D) Pharmacognosy
**Correct Answer:** B) Pharmacodynamics
,**Rationale:** Pharmacodynamics is the study of what the drug does to the
body—the biochemical and physiological effects of drugs and their
mechanisms of action, including receptor binding.
---
**3.** The "first-pass effect" refers to:
A) The drug being metabolized by the liver before reaching systemic
circulation
B) The drug binding to plasma proteins
C) The drug being excreted by the kidneys
D) The drug crossing the blood-brain barrier
**Correct Answer:** A) The drug being metabolized by the liver before
reaching systemic circulation
**Rationale:** The first-pass effect refers to the metabolism of an oral drug
by the liver before it reaches systemic circulation, reducing bioavailability.
Drugs administered via sublingual, buccal, or parenteral routes bypass this
effect.
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**4.** Bioavailability is defined as:
A) The time it takes for a drug to reach its maximum therapeutic response
B) The amount of active drug that reaches systemic circulation
C) The time it takes for a drug to elicit a therapeutic response
, D) The time a drug concentration is sufficient to elicit a response
**Correct Answer:** B) The amount of active drug that reaches systemic
circulation
**Rationale:** Bioavailability is the extent of drug absorption for a given drug
and route—the amount of active drug that reaches systemic circulation. It is
influenced by first-pass metabolism, drug formulation, and route of
administration.
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**5.** What is the term for the time it takes for a drug to reach its maximum
therapeutic response?
A) Onset
B) Duration
C) Peak
D) Half-life
**Correct Answer:** C) Peak
**Rationale:** Peak is the time it takes for a drug to reach its maximum
therapeutic response. Onset is the time to first response; duration is how
long the response lasts.
---
2026/2027 Chamberlain
1.** A nurse is reviewing pharmacology concepts. Which term describes what
the BODY does to the drug?
A) Pharmacodynamics
B) Pharmacotherapeutics
C) Pharmacokinetics
D) Pharmacognosy
**Correct Answer:** C) Pharmacokinetics
**Rationale:** Pharmacokinetics is the study of what the body does to the
drug, including absorption, distribution, metabolism, and excretion (ADME).
Pharmacodynamics is the study of what the drug does to the body.
---
**2.** Which term describes what the DRUG does to the body?
A) Pharmacokinetics
B) Pharmacodynamics
C) Pharmacotherapeutics
D) Pharmacognosy
**Correct Answer:** B) Pharmacodynamics
,**Rationale:** Pharmacodynamics is the study of what the drug does to the
body—the biochemical and physiological effects of drugs and their
mechanisms of action, including receptor binding.
---
**3.** The "first-pass effect" refers to:
A) The drug being metabolized by the liver before reaching systemic
circulation
B) The drug binding to plasma proteins
C) The drug being excreted by the kidneys
D) The drug crossing the blood-brain barrier
**Correct Answer:** A) The drug being metabolized by the liver before
reaching systemic circulation
**Rationale:** The first-pass effect refers to the metabolism of an oral drug
by the liver before it reaches systemic circulation, reducing bioavailability.
Drugs administered via sublingual, buccal, or parenteral routes bypass this
effect.
---
**4.** Bioavailability is defined as:
A) The time it takes for a drug to reach its maximum therapeutic response
B) The amount of active drug that reaches systemic circulation
C) The time it takes for a drug to elicit a therapeutic response
, D) The time a drug concentration is sufficient to elicit a response
**Correct Answer:** B) The amount of active drug that reaches systemic
circulation
**Rationale:** Bioavailability is the extent of drug absorption for a given drug
and route—the amount of active drug that reaches systemic circulation. It is
influenced by first-pass metabolism, drug formulation, and route of
administration.
---
**5.** What is the term for the time it takes for a drug to reach its maximum
therapeutic response?
A) Onset
B) Duration
C) Peak
D) Half-life
**Correct Answer:** C) Peak
**Rationale:** Peak is the time it takes for a drug to reach its maximum
therapeutic response. Onset is the time to first response; duration is how
long the response lasts.
---
