T2 EX5 L6 (SCHIZOPHRENIA PT. 2) (HOUSER) EXAM WITH
COMPLETE SOLUTIONS 100% VERIFIED!!! ALREADY GRADED A+
Preferred first-line options for first acute psychotic episode? - (answer)SGAs preferred
Aripiprazole, risperidone, ziprasidone recommended
T/F: Long-acting injectable antipsychotics (LAIAs) should be considered in all stages of schizophrenia. -
(answer)True
When do we consider clozapine? (three circumstances) - (answer)1. Consider when poor symptom
improvement w/ two different antipsychotic trials at appropriate dose and duration.
2. Decreasing suicidal behavior in stage 2
3. Can also be considered in stage 2 w/ patients that have a history of violence or comorbid substance
abuse.
Treatment goals during first week of antipsychotic therapy? - (answer)Decrease agitation, hostility,
combativeness, anxiety, tension, and aggression
Titrate medication to average effective dose over first few days
Normalization of sleep and eating patterns
Initial treatment election for antipsychotic therapy with SGAs should take into consideration what? -
(answer)Target symptoms (i.e., violent behavior)
Comorbidities, patient tolerability
Consider switching treatment if not effective within 3-4 weeks
Stabilization therapy for antipsychotics considerations? - (answer)Symptom improvement may occur
over 6-12 weeks
, T2 EX5 L6 (SCHIZOPHRENIA PT. 2) (HOUSER) EXAM WITH
COMPLETE SOLUTIONS 100% VERIFIED!!! ALREADY GRADED A+
First 2-3 weeks, goals should include *increased socialization, improvement in selfcare habits and mood*
Improvement in though disorders should follow *may take 6-8 weeks extra (total 20 weeks)*
After remission of first psychotic episode, therapy should be continued for at least... - (answer)18
months
Experts recommend antipsychotic treatment duration of at least how long in patients with an effective
medication response? - (answer)At least 5 years
Three different mechanisms of SGAs? - (answer)1. Antagonists of dopamine and serotonin (5-HT2a)
receptors
2. D2 antagonism with rapid dissociation
3. D2 partial agonism (aripiprazole, brexpiprazole, cariprazine)
Medications who fall into the "D2 antagonism with rapid dissociation" bucket? (four) -
(answer)Quetiapine
Clozapine
(Faster dissociation, weaker affinity for binding)
Risperidone
Paliperidone
(High potency SGAs)
SGAs class effect overview? (four) - (answer)1. Enhanced efficacy for treatment of negative symptoms
2. Low effect on serum prolactin (EXCEPT RISPERIDONE)
3. Low risk of EPS and TD (particularly clozapine, olanzapine)
COMPLETE SOLUTIONS 100% VERIFIED!!! ALREADY GRADED A+
Preferred first-line options for first acute psychotic episode? - (answer)SGAs preferred
Aripiprazole, risperidone, ziprasidone recommended
T/F: Long-acting injectable antipsychotics (LAIAs) should be considered in all stages of schizophrenia. -
(answer)True
When do we consider clozapine? (three circumstances) - (answer)1. Consider when poor symptom
improvement w/ two different antipsychotic trials at appropriate dose and duration.
2. Decreasing suicidal behavior in stage 2
3. Can also be considered in stage 2 w/ patients that have a history of violence or comorbid substance
abuse.
Treatment goals during first week of antipsychotic therapy? - (answer)Decrease agitation, hostility,
combativeness, anxiety, tension, and aggression
Titrate medication to average effective dose over first few days
Normalization of sleep and eating patterns
Initial treatment election for antipsychotic therapy with SGAs should take into consideration what? -
(answer)Target symptoms (i.e., violent behavior)
Comorbidities, patient tolerability
Consider switching treatment if not effective within 3-4 weeks
Stabilization therapy for antipsychotics considerations? - (answer)Symptom improvement may occur
over 6-12 weeks
, T2 EX5 L6 (SCHIZOPHRENIA PT. 2) (HOUSER) EXAM WITH
COMPLETE SOLUTIONS 100% VERIFIED!!! ALREADY GRADED A+
First 2-3 weeks, goals should include *increased socialization, improvement in selfcare habits and mood*
Improvement in though disorders should follow *may take 6-8 weeks extra (total 20 weeks)*
After remission of first psychotic episode, therapy should be continued for at least... - (answer)18
months
Experts recommend antipsychotic treatment duration of at least how long in patients with an effective
medication response? - (answer)At least 5 years
Three different mechanisms of SGAs? - (answer)1. Antagonists of dopamine and serotonin (5-HT2a)
receptors
2. D2 antagonism with rapid dissociation
3. D2 partial agonism (aripiprazole, brexpiprazole, cariprazine)
Medications who fall into the "D2 antagonism with rapid dissociation" bucket? (four) -
(answer)Quetiapine
Clozapine
(Faster dissociation, weaker affinity for binding)
Risperidone
Paliperidone
(High potency SGAs)
SGAs class effect overview? (four) - (answer)1. Enhanced efficacy for treatment of negative symptoms
2. Low effect on serum prolactin (EXCEPT RISPERIDONE)
3. Low risk of EPS and TD (particularly clozapine, olanzapine)
