MEDICAL GENETICS CHAPTER 20 ACTUAL TEST PAPER QUESTIONS AND SOLUTIONS GRADED A.pdf

MEDICAL GENETICS CHAPTER 20 ACTUAL
TEST PAPER QUESTIONS AND SOLUTIONS
GRADED A+

◉ chromosomal disorders.
Answer: entire chromosomes (or large segments) are missing,
duplicated, or otherwise altered


◉ single gene disorders.
Answer: single genes are altered
classified by the way they are inherited in families


◉ multifactorial disorders.
Answer: combination of multiple genetic & environmental causes


◉ mitochondrial disorders come from _______..
Answer: mother


◉ acquired somatic genetic diseases.
Answer: disease with a genetic basis but not hereditary

,◉ all genetic diseases involve defects at the _______ level..
Answer: cellular


◉ Where can errors occur?.
Answer: replication of genetic material
translation of genes into proteins
cell division


◉ chromatin.
Answer: makes up chromosomes
condenses before cell division to for chromosomes


◉ chromosomes.
Answer: contain genes


◉ genes.
Answer: basic unit of inheritance
segment of DNA


◉ how many pairs of chromosomes does each somatic cell have?.
Answer: 23 pairs

, ◉ how many total chromosomes does each somatic cell have?.
Answer: 46 total chromosomes


◉ haploid.
Answer: 1/2 number of chromosomes (23)


◉ the haploid # is maintained by ______..
Answer: meiosis


◉ histones.
Answer: DNA with 2 scaffold protein tetramers
involved in regulation of transcription of DNA
located in nucleus


◉ What are histones involved in?.
Answer: regulation of transcription of DNA


◉ DNA is a ______ molecule..
Answer: stable


◉ mutation.
Answer: permanent change in DNA sequence