CMN 572 CERTIFICATION EVALUATION
2026 SOLVED QUESTION SET GRADED A+
◉ Most common clinically significant HPV infection manifestations:.
Answer: Genital warts
Cervical cell abnormalities
◉ Genital Warts (HPV) types:.
Answer: Condylomata acuminata-Cauliflower-like appearance:Skin-
colored, pink, or hyperpigmented
Smooth papules-Usually dome-shaped and skin-colored
Flat papules-Macular to slightly raised
Flesh-colored, with smooth surface
More commonly found on internal structures
Keratotic warts-Thick horny layer that can resemble common warts
or seborrheic keratosis
Warts commonly occur in areas of coital friction.
◉ genital wart associated symptoms.
,Answer: Genital warts usually cause no symptoms other than the
warts themselves.
dyspareunia, pruritis, burning discomfort, discharge/bleeding if
around mucous membrane
◉ Cervical Cell Abnormalities.
Answer: Usually subclinical & caused by high risk HPV (16 &18)
Detected by Pap test, colposcopy, or biopsy
Most women infected with high-risk HPV types have normal Pap test
results
Often regress spontaneously without treatment
◉ Classification of Cervical Cell Abnormalities.
Answer: 2001 Bethesda System:
Atypical squamous cells (ASC):cells do not appear to be completely
normal.
ASC-US—atypical squamous cells of undetermined significance
[potential changes r/t HPV]
,ASC-H—atypical squamous cells cannot exclude a high-grade
squamous intraepithelial lesion[precancerous abnorms]
Low-grade squamous intraepithelial lesion (LSIL)--generally a
transient infection with a high-risk HPV type
High-grade squamous intraepithelial lesion (HSIL)--generally a
persistent infection with a high-risk HPV type with a higher risk for
progression to cervical cancer
◉ Diagnosis of Genital Warts: Do's/Dont's.
Answer: Diagnosis is usually made by visual inspection with bright
light.
Diagnosis can be confirmed by biopsy when:
Diagnosis is uncertain
Patient is immunocompromised
Warts are pigmented, indurated, or fixed
Lesions do not respond or worsen with standard treatment
There is persistent ulceration or bleeding
Use of type-specific HPV DNA tests for routine diagnosis and
management of genital warts is not recommended.
, Acetic acid evaluation (acetowhitening) of external genitalia is not
recommended.
◉ Molluscum contagiosum:.
Answer: papules with central dimple, caused by a pox virus; rarely
involves mucosal surfaces
◉ CDC-Recommended Regimens For External Genital Warts:
Patient-Applied & Provider Applied.
Answer: Patient Applied:
Podofilox 0.5% solution or gel (Condylox™)
Patients should apply solution with cotton swab or gel with a finger
to visible warts twice a day for 3 days, followed by 4 days of no
therapy.
Cycle may be repeated as needed up to 4 cycles.
OR
Imiquimod 3.75 or 5% cream (Aldara™)
Patients should apply cream once daily at bedtime, 3 times a week
for up to 16 weeks.
Treatment area should be washed with soap and water 6-10 hours
after application.
OR
Sinecatechins 15% ointment
Patients should apply the ointment 3 times daily for up to 16 weeks
2026 SOLVED QUESTION SET GRADED A+
◉ Most common clinically significant HPV infection manifestations:.
Answer: Genital warts
Cervical cell abnormalities
◉ Genital Warts (HPV) types:.
Answer: Condylomata acuminata-Cauliflower-like appearance:Skin-
colored, pink, or hyperpigmented
Smooth papules-Usually dome-shaped and skin-colored
Flat papules-Macular to slightly raised
Flesh-colored, with smooth surface
More commonly found on internal structures
Keratotic warts-Thick horny layer that can resemble common warts
or seborrheic keratosis
Warts commonly occur in areas of coital friction.
◉ genital wart associated symptoms.
,Answer: Genital warts usually cause no symptoms other than the
warts themselves.
dyspareunia, pruritis, burning discomfort, discharge/bleeding if
around mucous membrane
◉ Cervical Cell Abnormalities.
Answer: Usually subclinical & caused by high risk HPV (16 &18)
Detected by Pap test, colposcopy, or biopsy
Most women infected with high-risk HPV types have normal Pap test
results
Often regress spontaneously without treatment
◉ Classification of Cervical Cell Abnormalities.
Answer: 2001 Bethesda System:
Atypical squamous cells (ASC):cells do not appear to be completely
normal.
ASC-US—atypical squamous cells of undetermined significance
[potential changes r/t HPV]
,ASC-H—atypical squamous cells cannot exclude a high-grade
squamous intraepithelial lesion[precancerous abnorms]
Low-grade squamous intraepithelial lesion (LSIL)--generally a
transient infection with a high-risk HPV type
High-grade squamous intraepithelial lesion (HSIL)--generally a
persistent infection with a high-risk HPV type with a higher risk for
progression to cervical cancer
◉ Diagnosis of Genital Warts: Do's/Dont's.
Answer: Diagnosis is usually made by visual inspection with bright
light.
Diagnosis can be confirmed by biopsy when:
Diagnosis is uncertain
Patient is immunocompromised
Warts are pigmented, indurated, or fixed
Lesions do not respond or worsen with standard treatment
There is persistent ulceration or bleeding
Use of type-specific HPV DNA tests for routine diagnosis and
management of genital warts is not recommended.
, Acetic acid evaluation (acetowhitening) of external genitalia is not
recommended.
◉ Molluscum contagiosum:.
Answer: papules with central dimple, caused by a pox virus; rarely
involves mucosal surfaces
◉ CDC-Recommended Regimens For External Genital Warts:
Patient-Applied & Provider Applied.
Answer: Patient Applied:
Podofilox 0.5% solution or gel (Condylox™)
Patients should apply solution with cotton swab or gel with a finger
to visible warts twice a day for 3 days, followed by 4 days of no
therapy.
Cycle may be repeated as needed up to 4 cycles.
OR
Imiquimod 3.75 or 5% cream (Aldara™)
Patients should apply cream once daily at bedtime, 3 times a week
for up to 16 weeks.
Treatment area should be washed with soap and water 6-10 hours
after application.
OR
Sinecatechins 15% ointment
Patients should apply the ointment 3 times daily for up to 16 weeks
