CLINICAL PHARMACOLOGY COMPLETE
PREPARATION GUIDE WITH MEDICATION
CLASSIFICATIONS AND SAFE ADMINISTRATION
REVIEW
◉ What are the two meanings of the Greek word 'pharmakon'?
Answer: Remedy and poison.
◉ What is clinical pharmacology?
Answer: The study of drugs in the human body.
◉ Approximately what percentage of a nurse's time is spent on
medication activities?
Answer: 40%.
◉ What percentage of NCLEX Exam questions pertain to
pharmacologic concepts?
Answer: 13-19%.
◉ What are the properties of an ideal drug?
,Answer: Effective, safe, selective, reversible action, predictable, easy
to administer, freedom of interactions, low cost, chemically stable,
and possess a simple generic name.
◉ What is the therapeutic objective in pharmacology?
Answer: To provide maximum benefit with minimum harm to
clients.
◉ What is informed consent in drug research?
Answer: Patients have the right to be informed and participation is
voluntary.
◉ What are the four phases of human clinical experimentation?
Answer: Phase 1: Safety testing; Phase 2: Effectiveness and safety
evaluation; Phase 3: Confirm effectiveness and monitor side effects;
Phase 4: Post-marketing studies.
◉ What is the drug approval process guided by in the United States?
Answer: Federal legislation, specifically by the US Food and Drug
Administration (FDA).
◉ What does 'off-label use' mean?
Answer: Using a medication for a purpose other than its FDA-
approved indication.
, ◉ What is the difference between indication and contraindication?
Answer: Indication is the reason for taking the drug;
contraindication is a reason not to give the drug.
◉ What is the significance of the 1938 Federal Food, Drug, and
Cosmetic Act?
Answer: It empowered the FDA to ensure drug safety before
marketing.
◉ What does the term 'generic drug' refer to?
Answer: A drug that has the same active ingredients as a brand-
name drug but is usually less expensive.
◉ What is required for a generic drug to be considered
therapeutically equivalent to a brand-name drug?
Answer: It must demonstrate less than a 20% variance in drug
absorption, distribution, metabolism, and excretion levels.
◉ What is a notable concern regarding generic drugs?
Answer: They may use different chemical binders and fillers, which
can impact effectiveness in some patients.
◉ What is the role of the nurse in medication administration?
PREPARATION GUIDE WITH MEDICATION
CLASSIFICATIONS AND SAFE ADMINISTRATION
REVIEW
◉ What are the two meanings of the Greek word 'pharmakon'?
Answer: Remedy and poison.
◉ What is clinical pharmacology?
Answer: The study of drugs in the human body.
◉ Approximately what percentage of a nurse's time is spent on
medication activities?
Answer: 40%.
◉ What percentage of NCLEX Exam questions pertain to
pharmacologic concepts?
Answer: 13-19%.
◉ What are the properties of an ideal drug?
,Answer: Effective, safe, selective, reversible action, predictable, easy
to administer, freedom of interactions, low cost, chemically stable,
and possess a simple generic name.
◉ What is the therapeutic objective in pharmacology?
Answer: To provide maximum benefit with minimum harm to
clients.
◉ What is informed consent in drug research?
Answer: Patients have the right to be informed and participation is
voluntary.
◉ What are the four phases of human clinical experimentation?
Answer: Phase 1: Safety testing; Phase 2: Effectiveness and safety
evaluation; Phase 3: Confirm effectiveness and monitor side effects;
Phase 4: Post-marketing studies.
◉ What is the drug approval process guided by in the United States?
Answer: Federal legislation, specifically by the US Food and Drug
Administration (FDA).
◉ What does 'off-label use' mean?
Answer: Using a medication for a purpose other than its FDA-
approved indication.
, ◉ What is the difference between indication and contraindication?
Answer: Indication is the reason for taking the drug;
contraindication is a reason not to give the drug.
◉ What is the significance of the 1938 Federal Food, Drug, and
Cosmetic Act?
Answer: It empowered the FDA to ensure drug safety before
marketing.
◉ What does the term 'generic drug' refer to?
Answer: A drug that has the same active ingredients as a brand-
name drug but is usually less expensive.
◉ What is required for a generic drug to be considered
therapeutically equivalent to a brand-name drug?
Answer: It must demonstrate less than a 20% variance in drug
absorption, distribution, metabolism, and excretion levels.
◉ What is a notable concern regarding generic drugs?
Answer: They may use different chemical binders and fillers, which
can impact effectiveness in some patients.
◉ What is the role of the nurse in medication administration?
