What are the major functions of the α1 Increase vascular smooth muscle contraction, increase
receptor? pupillary dilator muscle contraction (mydriasis), increase
intestinal and bladder sphincter muscle contraction
What are the major functions of the α2 Decrease sympathetic outflow, decrease insulin release,
receptor? decrease lipolysis, increase platelet aggregation, decrease
aqueous humor production
,Pharmacology Nursing Q&A
What are the major functions of the β1 Increase heart rate, increase contractility, increase renin
receptor? release, increase lipolysis
What are the major functions of the β2 Vasodilation, bronchodilation, increase lipolysis, increase
receptor? insulin release, decrease uterine tone (tocolysis), ciliary
muscle relaxation, increase aqueous humor production
What are the major functions of the M1 CNS, enteric nervous system
receptor?
,Pharmacology Nursing Q&A
What are the major functions of the M2 Decrease heart rate and contractility of atria
receptor?
What are the major functions of the M3 Increase exocrine gland secretions (e.g., lacrimal, salivary,
receptor? gastric acid), increase gut peristalsis, increase bladder
contraction, increase bronchoconstriction, pupillary sphincter
muscle contraction (miosis), ciliary muscle contraction
(accommodation)
What are the major functions of the D1 Relaxes renal vascular smooth muscle
receptor?
, Pharmacology Nursing Q&A
What are the major functions of the D2 Modulates transmitter release, especially in the brain
receptor?
What are the major functions of the H1 Increase nasal and bronchial mucus production, increase
receptor? vascular permeability, contraction of bronchioles, pruritis, pain
What are the major functions of the H2 Increase gastric acid secretion
receptor?
What are the major functions of the V1 Increase vascular smooth muscle contraction
receptor?
What are the major functions of the V2 Increase H2O permeability and reabsorption in collecting
receptor? tubules of kidney (V2 is found in the "2" kidneys)
What receptors are associate with Gq? H1, α1, V1, M1, and M3