SLLE BLOOD BANK EXAM QUESTIONS WELL ANSWERED LATEST UPDATE 2026
Rh & ABO chromosomes - Answers Rh - chromosome 1
ABO - chromosome 9
A Antigen terminal sugar - Answers N-acetylgalactosamine
B antigen terminal sugar - Answers D-galactose
H antigen terminal sugar - Answers L-fucose
Blood groups with greatest amount of H antigen to least amount - Answers O > A2 > B > A2B > A1 >
A1B
Differentiating A1 from A2 - Answers Lectin
Individual with A2 blood type, which blood group should be transfused? - Answers O or A2
because individuals with A2 blood have an antibody against A1
No H antigen - Answers Bombay (hh) genotype
ABO antibodies - Answers IgM (Group A and Group B)
IgG (Group O)
Detection of antigen-antibody reactions in blood bank by two forms - Answers 1. Hemolysis
(activation of complement)
2. Agglutination (clumping)
Group I Discrepancies - Answers Missing or weak Antibodies
Due to Newborns, old age, lymphoma, BM transplant, or immunosuppressive drugs
Solution: Incubate at room temp for 15 minutes
Group II Discrepancies - Answers Missing or weak Antigens
Due to subgroups of A & B
Leukemia, Hodgkin's disease
Solution:
Wash cells with normal saline
Group III Discrepancies - Answers Plasma or protein abnormalities
Due to: Multiple Myeloma, Hodgkin's Lymphoma or Roleaux formation
Solution: Wash cells with saline or few drops, if agglutination is still there then its true agglutination
and clumping will remain
Group IV Discrepancies - Answers Miscellaneous problems
Could be due to viral or bacterial infection
stem cell transplantation
HLA chromosome - Answers Chromosome 6
MHC I - Answers a transmembrane glycoprotein, found on all nucleated cells
MHC II - Answers Found on antigen presenting cells (macrophages, B cells, and activated T cells;
signal helper T cells, dendritic cells, neutrophils)
MHC III - Answers involved in the production of components of the complement system and
cytokines
Anti-I - Answers Following an infection with mycoplasma pneumoniae
cause Cold Agglutinin Disease
Anti-i - Answers associated with infectious mononucleosis
Anti-P - Answers Produced in individuals with Paroxymal Cold Hemoglobinuria (PCH)
Also called Donath-Landsteiner antibody
Antigens located on Glycophorin A? - Answers M & N
Antigens located on Glycophorin B? - Answers S & s, U
Lewis system chromosome - Answers chromosome 19
Genes
Rh & ABO chromosomes - Answers Rh - chromosome 1
ABO - chromosome 9
A Antigen terminal sugar - Answers N-acetylgalactosamine
B antigen terminal sugar - Answers D-galactose
H antigen terminal sugar - Answers L-fucose
Blood groups with greatest amount of H antigen to least amount - Answers O > A2 > B > A2B > A1 >
A1B
Differentiating A1 from A2 - Answers Lectin
Individual with A2 blood type, which blood group should be transfused? - Answers O or A2
because individuals with A2 blood have an antibody against A1
No H antigen - Answers Bombay (hh) genotype
ABO antibodies - Answers IgM (Group A and Group B)
IgG (Group O)
Detection of antigen-antibody reactions in blood bank by two forms - Answers 1. Hemolysis
(activation of complement)
2. Agglutination (clumping)
Group I Discrepancies - Answers Missing or weak Antibodies
Due to Newborns, old age, lymphoma, BM transplant, or immunosuppressive drugs
Solution: Incubate at room temp for 15 minutes
Group II Discrepancies - Answers Missing or weak Antigens
Due to subgroups of A & B
Leukemia, Hodgkin's disease
Solution:
Wash cells with normal saline
Group III Discrepancies - Answers Plasma or protein abnormalities
Due to: Multiple Myeloma, Hodgkin's Lymphoma or Roleaux formation
Solution: Wash cells with saline or few drops, if agglutination is still there then its true agglutination
and clumping will remain
Group IV Discrepancies - Answers Miscellaneous problems
Could be due to viral or bacterial infection
stem cell transplantation
HLA chromosome - Answers Chromosome 6
MHC I - Answers a transmembrane glycoprotein, found on all nucleated cells
MHC II - Answers Found on antigen presenting cells (macrophages, B cells, and activated T cells;
signal helper T cells, dendritic cells, neutrophils)
MHC III - Answers involved in the production of components of the complement system and
cytokines
Anti-I - Answers Following an infection with mycoplasma pneumoniae
cause Cold Agglutinin Disease
Anti-i - Answers associated with infectious mononucleosis
Anti-P - Answers Produced in individuals with Paroxymal Cold Hemoglobinuria (PCH)
Also called Donath-Landsteiner antibody
Antigens located on Glycophorin A? - Answers M & N
Antigens located on Glycophorin B? - Answers S & s, U
Lewis system chromosome - Answers chromosome 19
Genes
