NURS8024 PHARM EXAM 1 QUESTIONS AND
ANSWERS 2026/2027 SOLVED 100%
CORRECT
◉ In Parkinson's disease the amount of __________ lost directly
correlates to severity of symptoms. Answer: Dopamine
◉ The goal of treatment for Parkinson's disease is to CURE and
REVERSE degeneration. T / F Answer: False - Tx focus is on
restoring balance
◉ Sinamet (Levodopa & Carbidopa) MOA includes: Answer: Assist
in conversion of levodopa to dopamine in the basal nigra - Increase in
body's production of dopamine
◉ How does Carbidopa help in Parkinson's disease? Answer:
Carbidopa enhances availability of levodopa to cross the BBB.
Decrease metabolism of levodopa in the GI system
◉ An NP understand that treatment effectiveness _____________
between the 3rd and 5th year of Parkinson treatment using sinemet.
Answer: Decreases
◉ Important Pt Ed on Levodopa: Answer: Take on an Empty Stomach
,◉ ADE with Levodopa include: Answer: CNS effects
(Visual/Auditory Hallucinations, AIM, depression, GI effects, Tachy,
Acute glaucoma
◉ Amantadine is used to treat? Answer: MINOR Parkinsons
◉ MOA for Amantadine includes: Answer: Enhances dopaminergic
neurotransmission, muscarininc blocking
◉ An NP would be cautious in prescribing Amantadine for minor
Parkinson's in a patient with what dx? Answer: Seizure D/O & CHF
◉ Name two dopamine receptor agonists: Answer: Ropinirole &
Pramipexole
◉ Name the one anticholingeric for EPS / Parkinsons Answer:
Cogentin / Benzotropine
◉ ADE of dopamine receptor agonists include: Answer: GI, Postural
HYPO, Dyskinesias, confusion, delusions, hallucinations,
IMPULSIVITY
◉ Ropinirole and Pramipexole CAUSE: Answer: IMPULSIVITY
, ◉ Cogentin / Benzotropine is an________________ drug Answer:
Anticholinergic
◉ MAO-B Inbhitors Answer: Monamine Oxidase B Inhibitors
◉ When prescribing MAO-B Inhibitors use CAUTION with what
two medications? Answer: Fluoxetine or Meperidine (Prozac or
Demerol)
◉ MAO-B Inhibitors include: Answer: Selegiline (Eldepryl) &
Rasagiline (Azilect)
◉ Use MAO-B Inhibitors _____________ and adjunct with
__________. Answer: Early ; Levodopa
◉ COMT (Catehcol-O-Methyltransferase Inhibitors) Answer: Help
with uptake of Levodopa which increases dopamine in CNS
◉ CAUTION when using _______________ & ___________ as both
are major enzymes that metabolize catecholamines. Answer: MAO-B
and COMT
◉ Anticholinergics in Parkinson's disease are prescribed because........
Answer: Decrease Tremors
Decrease Rigidity
ANSWERS 2026/2027 SOLVED 100%
CORRECT
◉ In Parkinson's disease the amount of __________ lost directly
correlates to severity of symptoms. Answer: Dopamine
◉ The goal of treatment for Parkinson's disease is to CURE and
REVERSE degeneration. T / F Answer: False - Tx focus is on
restoring balance
◉ Sinamet (Levodopa & Carbidopa) MOA includes: Answer: Assist
in conversion of levodopa to dopamine in the basal nigra - Increase in
body's production of dopamine
◉ How does Carbidopa help in Parkinson's disease? Answer:
Carbidopa enhances availability of levodopa to cross the BBB.
Decrease metabolism of levodopa in the GI system
◉ An NP understand that treatment effectiveness _____________
between the 3rd and 5th year of Parkinson treatment using sinemet.
Answer: Decreases
◉ Important Pt Ed on Levodopa: Answer: Take on an Empty Stomach
,◉ ADE with Levodopa include: Answer: CNS effects
(Visual/Auditory Hallucinations, AIM, depression, GI effects, Tachy,
Acute glaucoma
◉ Amantadine is used to treat? Answer: MINOR Parkinsons
◉ MOA for Amantadine includes: Answer: Enhances dopaminergic
neurotransmission, muscarininc blocking
◉ An NP would be cautious in prescribing Amantadine for minor
Parkinson's in a patient with what dx? Answer: Seizure D/O & CHF
◉ Name two dopamine receptor agonists: Answer: Ropinirole &
Pramipexole
◉ Name the one anticholingeric for EPS / Parkinsons Answer:
Cogentin / Benzotropine
◉ ADE of dopamine receptor agonists include: Answer: GI, Postural
HYPO, Dyskinesias, confusion, delusions, hallucinations,
IMPULSIVITY
◉ Ropinirole and Pramipexole CAUSE: Answer: IMPULSIVITY
, ◉ Cogentin / Benzotropine is an________________ drug Answer:
Anticholinergic
◉ MAO-B Inbhitors Answer: Monamine Oxidase B Inhibitors
◉ When prescribing MAO-B Inhibitors use CAUTION with what
two medications? Answer: Fluoxetine or Meperidine (Prozac or
Demerol)
◉ MAO-B Inhibitors include: Answer: Selegiline (Eldepryl) &
Rasagiline (Azilect)
◉ Use MAO-B Inhibitors _____________ and adjunct with
__________. Answer: Early ; Levodopa
◉ COMT (Catehcol-O-Methyltransferase Inhibitors) Answer: Help
with uptake of Levodopa which increases dopamine in CNS
◉ CAUTION when using _______________ & ___________ as both
are major enzymes that metabolize catecholamines. Answer: MAO-B
and COMT
◉ Anticholinergics in Parkinson's disease are prescribed because........
Answer: Decrease Tremors
Decrease Rigidity
