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Edexcel IGCSE Biology (Higher Tier) — Complete Revision Guide Paper 1 (Topics 1–3): Cells, Nutrition, Reproduction & Genetics

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A complete, exam-focused revision guide covering Topics 1–3 of the Edexcel IGCSE Biology (Higher Tier) Paper 1 specification: The Nature and Variety of Living Organisms, Structures and Functions in Living Organisms, and Reproduction and Inheritance. What's included: - Clear, concise notes on every sub-topic — cell structure, classification, diffusion/osmosis/active transport, photosynthesis, digestion, respiration, gas exchange, transport systems, reproduction, mitosis vs meiosis, genetics and Punnett squares, and natural selection - Highlighted definition boxes for every key term you need to know - "Common mistake" call-outs flagging exactly where students lose marks - Exam-style practice questions with full mark-scheme-style answers at the end of every topic - Laid out in a clean, colour-coded design that's actually enjoyable to revise from — not a wall of text Written by a current Edexcel IGCSE student, so the level of detail and phrasing matches what you'll actually be tested on. Perfect for building revision notes, last-minute exam prep, or filling gaps in your understanding.

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EDEXCEL
IGCSE
BIOLOGY
REVISION GUIDE

, Topic 1: The Nature and
Variety of Living
Organisms
1.1 Characteristics of living organisms



All living organisms share seven life processes. A useful mnemonic is MRS GREN:

Movement — an action by an organism causing a change of position or place
Respiration — the chemical reactions in cells that break down nutrient molecules and release
energy
Sensitivity — the ability to detect and respond to changes in the environment
Growth — a permanent increase in size
Reproduction — processes that make more of the same kind of organism
Excretion — removal from organisms of the waste products of metabolism, toxic materials, and
substances in excess of requirements
Nutrition — taking in of materials for energy, growth and development



1.2 Cell structure

Animal and plant cells share some structures but differ in others. This is a very common exam
comparison question.

Nucleus: Contains genetic material (DNA) that controls the cell's activities
Cytoplasm: Gel-like substance where most chemical reactions happen
Cell membrane: Controls what enters and leaves the cell
Mitochondria: Site of aerobic respiration — releases energy
Ribosomes: Site of protein synthesis

Plant cells additionally have:

Cell wall (made of cellulose) — provides structural support
Chloroplasts — contain chlorophyll, site of photosynthesis
Permanent vacuole — contains cell sap, helps maintain turgor pressure



1.3 Classification

Organisms are classified into groups based on shared features. The hierarchy, from largest to
smallest group, is:

Kingdom → Phylum → Class → Order → Family → Genus → Species

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August 19, 2026
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