for Molecular Biology of the Cell, 6th Edition by Alberts
| Chapters 1–24 | Questions & Answers with Rationales
RESOURCE FEATURES x
• Chapters 1–24
• Practice questions and answers
• Detailed rationales and explanations
• Molecular and cellular biology review
• Concept-based learning
• Application and critical-thinking questions
• Genetics and gene-expression review
• Cell-signaling and cell-cycle concepts
• Exam preparation for biology and life-science courses
, MOLECULAR BIOLOGY OF THE CELL, SIXTH EDITION xc xc xc xc xc xc
CHAPTER 1: CELLS AND GENOMES xc x c xc x c x c
© cGarland cScience c2015
x x x
1 Scientists cdiscover cmore cthan cten cthousand cnew cspecies cof cliving corganisms cevery
x x x x x x x x x x x
cyear.
x c What cis cshared cbetween call cof cthese corganisms?
x x x x x x x x
A. They care cmade cof ccells, cwhose cnuclei cenclose ctheir cDNA.
x x x x x x x x x
B. They cobtain ctheir cenergy cfrom csunlight.
x x x x x
C. They cproduce cand cuse cadenosine ctriphosphate c(ATP).
x x x x x x
D. Their cgenome ccontains cat cleast c1000 cgenes.
x x x x x x
E. All cof cthe cabove.
x x x
2 All ccells c…
x x
A. have cmembrane ctransport cproteins.
x x x
B. synthesize cproteins con cthe cribosome. x x x x
C. replicate ctheir cgenome cby cDNA cpolymerization.
x x x x x
D. transcribe ctheir cgenetic cinformation cby cRNA cpolymerization.
x x x x x x
E. All cof cthe cabove.
x x x
3 Imagine ca csegment cof cDNA c(within ca cgene) cencoding ca ccertain camount cof
x x x x x x x x x x x x
cinformation cin cits cnucleotide csequence. cWhen cthis csegment cis cfully ctranscribed cinto cmRNA
x x x x x x x x x x x x x
cand cthen ctranslated cinto cprotein, cin cgeneral, c…
x x x x x x x x
A. the cprotein csequence cwould ccarry cmore cinformation ccompared cto cthe cDNA cand
x x x x x x x x x x x
cmRNA csequences, cbecause cits calphabet chas c20 cletters.
x x x x x x x x
x c B. x cthe cprotein csequence cwould ccarry cless cinformation ccompared cto cthe cDNA cand
x x x x x x x x x x x
x cmRNA csequences, cbecause cseveral ccodons ccan ccorrespond cto cone camino cacid.
x x x x x x x x x x
C. the camount cof cinformation cin cthe cmRNA csequence cis clower, cbecause cthe cmRNA
x x x x x x x x x x x x
chas cbeen ctranscribed cusing conly cone cof cthe cDNA cstrands cas cthe ctemplate.
x x x x x x x x x x x x x
D. the camount cof cinformation cin cthe cmRNA csequence cis chigher, cbecause cseveral
x x x x x x x x x x x
cmRNA cmolecules ccan cbe ctranscribed cfrom cone cDNA cmolecule.
x x x x x x x x x
4 Which cof cthe cfollowing cprocesses cthat chappens cinside ca ccell cDOES cNOT cnormally
x x x x x x x x x x x x
crequire cconsumption cof cfree cenergy cby cthe ccell?
x x x x x x x x
, A. Replication cof cthe cgenetic cmaterial x x x x
B. Import cof cnutrients cfrom cthe cenvironment
x x x x x
C. Diffusion cof csmall cmolecules cwithin cthe ccell x x x x x x
D. Regulation cof cgene cexpression x x x
E. Synthesis cof cenzymes cthat ccatalyze ccellular creactions
x x x x x x
5 Which cof cthe cfollowing cwould cyou cN c OT cexpect cto cfind cin ca cbacterial ccell?
x x x x x x x x x x x x x x
A. Swimming cusing cflagella x x
B. Having ca ccell cwall caround cthe cplasma cmembrane x x x x x x x
xc C. c ATP cproduction cin cmitochondria
x x x x
D. Protein cproduction con cthe cribosome x x x x
E. Sexual cexchange cof cDNA cwith cother cbacteria x x x x x x
6 To ctrace cfamily crelationships cbetween cdistantly crelated corganisms csuch cas chumans,
x x x x x x x x x x
calgae, cbacteria, cand carchaea, cone cshould ccompare ctheir cgenomes cin cregions c…
x x x x x x x x x x x x
A. that cevolve crapidly. x x
B. that chave ca chigher cmutation crate.
x x x x x
C. that ccode cfor cproteins.
x x x
D. where cmutations care chardly ctolerated.
x x x x
E. where cmost cmutations care cselectively cneutral.
x x x x x
7 Laboratory cstrains cof cthe cmodel corganism cEscherichia ccoli cthat care cresistant cto
x x x x x x x x x x x
cantibiotics care cvery coften cused cin cresearch claboratories cas cwell cas cin cthe cbiotechnology
x x x x x x x x x x x x x x
cindustry.
x c If ccultures
x c of csuch cbacteria cwere callowed cto ccontaminate cthe cenvironment
x x x x x x x x x x
cuncontrollably, cit cis cpossible cthat
x c at csome cpoint, cpathogenic cbacteria csuch cas cNeisseria
x x x x x x x x x x x x
cmeningitidis c(which ccauses cmeningitis cand ccan ccause cdeath, cespecially cin cchildren) ccould
x x x x x x x x x x x x
cacquire cthe csame cantibiotic-resistance cgene,
x x x c causing ca cmeningitis coutbreak cthat cis cdifficult
x x x x x x x x x
cto ctreat. cIn cthis cscenario, cwhich cof cthe cfollowing cmechanisms cis ca cmore clikely csource cof
x x x x x x x x x x x x x x x x
cthe cantibiotic-resistance cgene cin cN. cmeningitidis?
x x x x x x
A. Random cnew cgene cgeneration x x x
B. Intragenic cmutation x
C. Gene cduplication x
D. DNA csegment cshuffling x x
E. Horizontal cgene ctransfer x x
8 A cvirus c…
x x
A. is ca ctype cof ccell.x x x x
, B. has cgenetic cmaterial cmade cof cproteins.
x x x x x
C. can conly cinfect ca csingle chost cspecies.
x x x x x x
D. can cact cas ca cvector cfor cgene ctransfer.
x x x x x x x
E. cannot cpersist cin cits chost cfor cmore cthan cone ccell cgeneration.
x x x x x x x x x x
9 Which cof cthe cfollowing cdoes cNOT ctypically cinvolve chorizontal cgene ctransfer?
x x x x x x x x x x
A. Sexual creproduction cin chumans x x x
B. Bacteriophage cinfection cof cbacteria x x x
C. The cevolutionary chistory cof cthe ceukaryotic ccell
x x x x x x
D. The caccidental cduplication cof ca csmall cregion cof ca cbacterial cchromosome cfollowed
x x x x x x x x x x x
cby c cell cdivision
x x x
E. Introduction cof cplasmids cinto cbacteria cin ca claboratory x x x x x x x
10 Gene cduplication ccan cgive crise cto chomologous cgenes cthat care cpart cof cgene cfamilies.
x x x x x x x x x x x x x
cFor cexample, cthere care csix cactin cgenes cin cthe cgenome cof cmost cmammalian cspecies. cIn
x x x x x x x x x x x x x x x
chumans, cthe cACTB cgene, cwhich cencodes ca ccytoskeletal cactin, cis cexpressed cubiquitously,
x x x x x x x x x x x x
cwhile cACTC1 cis cexpressed cmainly cin ccardiac ccells. cAlthough cbacteria clack cthe ceukaryotic
x x x x x x x x x x x x x
ccytoskeletal
x c organization, cthe cbacterial cMreB cgene cbears crecognizable csequence csimilarity
x x x x x x x x x
cto cmammalian cactin cgenes cand ccodes cfor ca cprotein cthat cis csimilar cto cactin cin cstructure cand
x x x x x x x x x x x x x x x x x
cfunction. cWhich cof cthe cfollowing cstatements cis ctrue cabout cthese cgenes?
x x x x x x x x x x x
A. ACTB cis chomologous cto cACTC1 cbut cnot cto cMreB.
x x x x x x x x
B. ACTB cis corthologous cto cACTC1 cbut cnot cto cMreB.
x x x x x x x x
C. ACTB cis cparalogous cto cACTC1 cbut cnot cto cMreB.
x x x x x x x x
D. MreB cis corthologous cto cACTB cbut cnot cto cACTC1.
x x x x x x x x
E. ACTB cis cparalogous cto cboth cACTC1 cand cMreB.
x x x x x x x
11 Out cof cnearly c5000 cprotein-coding cgene cfamilies, cthere cis ca cset cof cnearly c300
x x x x x x x x x x x x x
cconserved cgene cfamilies cthat care cfound cin cspecies cfrom call cdomains cof clife. cWhen cone
x x x x x x x x x x x x x x x
xc looks cat cthe cgeneral cfunctions cassigned cto cthese cgene cfamilies, cit cis cfound cthat c…
x x x x x x x x x x x x x x
A. the cmajority cof cthem cfunction cin ccell-to-cell csignaling.
x x x x x x x
B. the cmajority cof cthem care cpoorly ccharacterized.
x x x x x x
C. more c than c one-third c of c them c are c involved c in c translation c or c amino c acid
x x x x x x x x x x x
c transport c and cm c etabolism.
x x x x
D. more c than c one-half c of c the c shared c families c are c involved c in c DNA
x x x x x x x x x x
c replication c and
x c transcription. x x
E. Nearly call cof cthem care cinvolved cin cenergy cproduction cand ccarbohydrate cmetabolism.
x x x x x x x x x x x