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Med-Surg II HESI – Set 3 | Questions & Answers with Detailed Rationales | Nursing Study Guide 2026

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Prepare for Med-Surg II HESI Set 3 with a comprehensive nursing study and practice resource featuring practice questions, answers, and detailed rationales. Designed for nursing students reviewing advanced adult medical-surgical concepts, this resource supports clinical judgment, patient assessment, prioritization, intervention selection, and patient safety.

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HESI
Med-Surg II– Set 3 | Questions & Answers with
x x x x x x x x




x Detailed Rationales | Nursing Study Guide 2026
x x x x x x




RESOURCE FEATURES x




• Med-Surg II HESI Set 3 practice questions
x x x x x x x




• Answers for self-assessment
x x x




• Detailed rationales and explanations
x x x x




• Clinical scenario-based questions
x x x




• Prioritization and delegation practice x x x x




• Adult medical-surgical review
x x x




• NCLEX-style clinical judgment x x x




• 2026 exam preparation
x x

, Med-Surg II HESI – Set 3 | Questions & x x x x x x x x




x Answers with Detailed Rationales | Nursing x x x x x




x Study Guide 2026 x x




1. Angiotensin-converting enzyme (ACE) inhibitors may be prescribed
x x x x x x x




x for the client with diabetes mellitus to reduce vascular changes and
x x x x x x x x x x




x possibly prevent or delay development of:
x x x x x




1. Chronic obstructive pulmonary disease (COPD).
x x x x




2. Pancreatic cancer. x




3. Renal failure. x




4. Cerebrovascular accident. x




Correct Answer: 3 x x




Rationale: ACE inhibitors reduce intraglomerular pressure and have
x x x x x x x




renoprotective effects. They are first-line agents to slow the progression of
x x x x x x x x x x x




diabetic nephropathy (renal failure). They do not directly affect COPD,
x x x x x x x x x x




pancreatic cancer, or CVA prevention beyond general blood-pressure
x x x x x x x x




control.
x




2. The nurse should teach the diabetic client that which of the
x x x x x x x x x x x




x following is the most common symptom of hypoglycemia?
x x x x x x x




1. Nervousness.
2. Anorexia.

, 3. Kussmaul's respirations. x




4. Bradycardia.

Correct Answer: 1 x x




Rationale: Nervousness, along with tremors, diaphoresis, and palpitations,
x x x x x x x




are adrenergic symptoms of hypoglycemia caused by the counter-regulatory
x x x x x x x x x




epinephrine release. Anorexia is not typical; Kussmaul’s respirations occur in
x x x x x x x x x x




DKA (hyperglycemia); bradycardia is not a common hypoglycemic sign
x x x x x x x x x




(tachycardia is more typical).
x x x x




3. The nurse is assessing the client's use of medications. Which of the
x x x x x x x x x x x x




x following medications may cause a complication with the treatment
x x x x x x x x




x plan of a client with diabetes?
x x x x x




1. Aspirin.
2. Steroids.
3. Sulfonylureas.
4. Angiotensin-converting enzyme (ACE) inhibitors. x x x




Correct Answer: 2 x x




Rationale: Corticosteroids (steroids) increase blood glucose by promoting
x x x x x x x




gluconeogenesis and insulin resistance, often requiring dose adjustments of
x x x x x x x x x




hypoglycemic agents. Aspirin and ACE inhibitors are generally safe (even
x x x x x x x x x x




beneficial); sulfonylureas are anti-diabetic agents themselves.
x x x x x x




4. A client with type 1 diabetes mellitus has influenza. The nurse
x x x x x x x x x x x




x should instruct the client to:
x x x x




1. Increase the frequency of self-monitoring (blood glucose testing).
x x x x x x x

, 2. Reduce food intake to diminish nausea. x x x x x




3. Discontinue that dose of insulin if unable to eat. x x x x x x x x




4. Take half of the normal dose of insulin.
x x x x x x x




Correct Answer: 1 x x




Rationale: Illness (infection) increases stress hormones, raising blood
x x x x x x x




glucose. The client should test more frequently (every 2–4 hours) to guide
x x x x x x x x x x x x




insulin adjustments. Insulin should never be stopped (risk of DKA); the client
x x x x x x x x x x x x




should try to maintain carbohydrate intake with sick-day rules.
x x x x x x x x x




5. Which of the following is a priority goal for the diabetic client who
x x x x x x x x x x x x x




x is taking insulin and has nausea and vomiting from a viral illness or
x x x x x x x x x x x x




x influenza?

1. Obtaining adequate food intake. x x x




2. Managing own health. x x




3. Relieving pain. x




4. Increasing activity. x




Correct Answer: 1 x x




Rationale: During illness, maintaining carbohydrate intake is crucial to
x x x x x x x x




prevent hypoglycemia (if taking insulin) and ketoacidosis. Even with nausea,
x x x x x x x x x x




the client should consume small, frequent portions of easy-to-digest
x x x x x x x x x




carbohydrates. Pain relief and activity are secondary.
x x x x x x x




6. A client with diabetes begins to cry and says, "I just cannot stand the
x x x x x x x x x x x x x x




x thought of having to give myself a shot every day." Which of the
x x x x x x x x x x x x




x following would be the best response by the nurse?
x x x x x x x x

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