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Med-Surg II HESI – Set 2 | Questions & Answers with Detailed Rationales | Nursing Study Guide 2026

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Prepare for Med-Surg II HESI Set 2 with a comprehensive nursing study and practice resource featuring practice questions, answers, and detailed rationales. Designed for nursing students reviewing advanced adult medical-surgical concepts, this resource emphasizes clinical judgment, patient assessment, prioritization, interventions, and patient safety.

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HESI
Med-Surg II – Set 2 | Questions & Answers with
x x x x x x x x x




x Detailed Rationales | Nursing Study Guide 2026
x x x x x x




RESOURCE FEATURES x




• Med-Surg II HESI Set 2 practice questions
x x x x x x x




• Answers for self-assessment
x x x




• Detailed rationales and explanations
x x x x




• Clinical scenario-based practice
x x x




• Priority and delegation questions
x x x x




• Adult medical-surgical review
x x x




• NCLEX-style clinical judgment x x x




• 2026 exam preparation
x x

, Med-Surg II HESI – Set 2 | Questions & Answers x x x x x x x x x




with Detailed Rationales | Nursing Study Guide
x x x x x x x




x 2026
1. The nurse is assessing a 48-year-old client with a history of smoking
x x x x x x x x x x x x




x during a routine clinic visit. The client, who exercises regularly, reports
x x x x x x x x x x




x having pain in the calf during exercise that disappears at rest. Which of
x x x x x x x x x x x x




x the following findings requires further evaluation?
x x x x x




1. Heart rate 57 bpm. x x x




2. SpO₂ of 94% on room air. x x x x x




3. Blood pressure 134/82. x x




4. Ankle-brachial index of 0.65. x x x




Correct Answer: 4 x x




Rationale: An ABI of 0.65 is significantly below the normal range (1.0–1.4)
x x x x x x x x x x x




and indicates moderate-to-severe peripheral arterial disease. The calf pain
x x x x x x x x x




with exercise that resolves with rest (intermittent claudication) is classic for
x x x x x x x x x x x




PAD, but the ABI provides objective evidence. The other findings are within
x x x x x x x x x x x x




acceptable limits (heart rate 57 can be normal in a fit person; SpO₂ 94% is
x x x x x x x x x x x x x x x




acceptable; BP 134/82 is prehypertension but not the priority).
x x x x x x x x x




2. A client with peripheral vascular disease has undergone a right
x x x x x x x x x x




x femoral-popliteal bypass graft. The blood pressure has decreased from x x x x x x x x




x 124/80 to 94/62. What should the nurse assess first?
x x x x x x x x

, 1. IV fluid solution.
x x




2. Pedal pulses. x




3. Nasal cannula flow rate. x x x




4. Capillary refill. x




Correct Answer: 2 x x




Rationale: A drop in blood pressure after vascular surgery may indicate
x x x x x x x x x x




hemorrhage or graft occlusion. The priority is to assess distal perfusion by
x x x x x x x x x x x x




palpating pedal pulses. If pulses are absent or diminished, the graft may be
x x x x x x x x x x x x x




thrombosed, requiring immediate intervention. IV fluid and oxygen are
x x x x x x x x x




important but come after a focused vascular assessment.
x x x x x x x x




3. An overweight client taking warfarin (Coumadin) has dry skin due to
x x x x x x x x x x x




x decreased arterial blood flow. What should the nurse instruct the
x x x x x x x x x




x client to do? Select all that apply.
x x x x x x




1. Apply lanolin or petroleum jelly to intact skin.
x x x x x x x




2. Follow a reduced-calorie, reduced-fat diet.
x x x x




3. Inspect the involved areas daily for new ulcerations.
x x x x x x x




4. Instruct the client to limit activities of daily living (ADLs).
x x x x x x x x x




5. Use an electric razor to shave.
x x x x x




Correct Answers: 1, 2, 3, 5
x x x x x




Rationale:

• 1: Emollients help prevent skin cracking and infection.
x x x x x x x




• 2: Weight loss reduces cardiovascular risk and improves lipid profiles.
x x x x x x x x x




• 3: Daily skin inspection is essential to catch early ulcers.
x x x x x x x x x

, • 4: Limiting ADLs is incorrect; moderate activity (especially walking) is
x x x x x x x x x




encouraged for PAD.
x x x




• 5: Electric razors reduce the risk of cuts and bleeding in a client on
x x x x x x x x x x x x x




warfarin.
x




4. The nurse is caring for a client with peripheral artery disease who has
x x x x x x x x x x x x x




x recently been prescribed clopidogrel (Plavix). The nurse understands
x x x x x x x




x that more teaching is needed when the client states:
x x x x x x x x




1. "I should not be surprised if I bruise easier or if my gums bleed a little
x x x x x x x x x x x x x x x




when brushing my teeth."
x x x x




2. "It doesn't really matter if I take this medicine with or without food,
x x x x x x x x x x x x




whatever works best for my stomach."
x x x x x x




3. "I should stop taking Plavix if it makes me feel weak and dizzy."
x x x x x x x x x x x x




4. "The doctor prescribed this medicine to make my platelets less likely to
x x x x x x x x x x x




stick together and help prevent clots from forming."
x x x x x x x x




Correct Answer: 3 x x




Rationale: Weakness and dizziness may indicate bleeding (e.g.,
x x x x x x x




gastrointestinal bleed) or other adverse effects, but the client should not
x x x x x x x x x x x




stop Plavix abruptly; they should notify the healthcare provider immediately.
x x x x x x x x x x




Stopping an antiplatelet agent increases the risk of thrombosis. The other
x x x x x x x x x x x




statements are correct: bruising/bleeding gums are expected; food does not
x x x x x x x x x x




affect absorption; and the action is antiplatelet.
x x x x x x x




5. A client is receiving Cilostazol (Pletal) for peripheral arterial disease
x x x x x x x x x x




x causing intermittent claudication. The nurse determines this
x x x x x x




x medication is effective when the client reports which of the following?
x x x x x x x x x x

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