NURS 6501 Exam 3 | NURS 6501 Advanced
Pathophysiology | Actual Q&A with Rationale (NURS
6501 Exam 3) | Walden
Section A: Multiple Choice (30 questions)
Q1. Which neurotransmitter is primarily deficient in Parkinson’s disease?
A. Acetylcholine
B. Dopamine ✅
C. Serotonin
D. GABA
Rationale: Parkinson’s disease results from degeneration of dopaminergic neurons in
the substantia nigra.
Q2. Which type of hypersensitivity reaction is mediated by IgE?
A. Type I ✅
B. Type II
C. Type III
D. Type IV
Rationale: Type I hypersensitivity involves IgE antibodies triggering mast cell
degranulation (e.g., allergies, anaphylaxis).
Q3. Which condition is characterized by demyelination of CNS neurons?
A. Multiple sclerosis ✅
B. Guillain-Barré syndrome
C. Myasthenia gravis
, D. ALS
Rationale: MS is an autoimmune disorder causing CNS demyelination, leading to
sensory and motor deficits.
Q4. Which GI disorder is associated with “skip lesions” and transmural inflammation?
A. Ulcerative colitis
B. Crohn’s disease ✅
C. IBS
D. Diverticulitis
Rationale: Crohn’s disease features patchy “skip lesions” and full-thickness
inflammation.
Q5. Which electrolyte imbalance is common in Addison’s disease?
A. Hypernatremia
B. Hyponatremia ✅
C. Hypokalemia
D. Hypocalcemia
Rationale: Addison’s disease causes aldosterone deficiency → sodium loss
(hyponatremia) and potassium retention (hyperkalemia). (Both hyponatremia and
hyperkalemia are correct; the single best answer here is hyponatremia.)
Q6. Which respiratory condition is characterized by reversible airway obstruction?
A. COPD
B. Asthma ✅
C. Pulmonary fibrosis
D. Emphysema
Pathophysiology | Actual Q&A with Rationale (NURS
6501 Exam 3) | Walden
Section A: Multiple Choice (30 questions)
Q1. Which neurotransmitter is primarily deficient in Parkinson’s disease?
A. Acetylcholine
B. Dopamine ✅
C. Serotonin
D. GABA
Rationale: Parkinson’s disease results from degeneration of dopaminergic neurons in
the substantia nigra.
Q2. Which type of hypersensitivity reaction is mediated by IgE?
A. Type I ✅
B. Type II
C. Type III
D. Type IV
Rationale: Type I hypersensitivity involves IgE antibodies triggering mast cell
degranulation (e.g., allergies, anaphylaxis).
Q3. Which condition is characterized by demyelination of CNS neurons?
A. Multiple sclerosis ✅
B. Guillain-Barré syndrome
C. Myasthenia gravis
, D. ALS
Rationale: MS is an autoimmune disorder causing CNS demyelination, leading to
sensory and motor deficits.
Q4. Which GI disorder is associated with “skip lesions” and transmural inflammation?
A. Ulcerative colitis
B. Crohn’s disease ✅
C. IBS
D. Diverticulitis
Rationale: Crohn’s disease features patchy “skip lesions” and full-thickness
inflammation.
Q5. Which electrolyte imbalance is common in Addison’s disease?
A. Hypernatremia
B. Hyponatremia ✅
C. Hypokalemia
D. Hypocalcemia
Rationale: Addison’s disease causes aldosterone deficiency → sodium loss
(hyponatremia) and potassium retention (hyperkalemia). (Both hyponatremia and
hyperkalemia are correct; the single best answer here is hyponatremia.)
Q6. Which respiratory condition is characterized by reversible airway obstruction?
A. COPD
B. Asthma ✅
C. Pulmonary fibrosis
D. Emphysema
