ROBBINS BASIC PATHOLOGY 10TH EDITION
FINAL PAPER EXAM PREP QUESTIONS AND
ANSWERS GUARANTEED TO PASS
◉ What is transcytosis?
Answer: moving substances through endothelial cells
◉ What mediator promotes vascular leakage?
Answer: VEGF (vascular endothelial growth factor) via
vesiculovacuolar organelle
◉ List the 7 steps in the cellular events of inflammation in order.
Answer: 1)Margination
2)rolling
3)adhesion
4)transmigration
5)chemotaxis
6)activation
7)phagocytosis
◉ Why are new blood vessels leaky?
, Answer: they lack intercellular junctions
◉ What is the most important feature of inflammation?
Answer: -the recruit of leukocytes to affected tissues
◉ What is margination?
Answer: when blood is viscous due to inflammation WBCS are
pushed to the edges of vessels because of slow-moving RBC that are
small and therefore take the central region of the vessel
◉ What is another name for rouleaux-formation?
Answer: margination
◉ What is rolling?
Answer: WBCs temporarily adhere to endothelial cells via weak
interactions
◉ E-selections and P-selectins on the endothelial cells bind what
protein on leukocytes?
Answer: Sialyl-Lewis protein
◉ L-selectins on the leukocyte bind which receptor on the
endothelial cells?
FINAL PAPER EXAM PREP QUESTIONS AND
ANSWERS GUARANTEED TO PASS
◉ What is transcytosis?
Answer: moving substances through endothelial cells
◉ What mediator promotes vascular leakage?
Answer: VEGF (vascular endothelial growth factor) via
vesiculovacuolar organelle
◉ List the 7 steps in the cellular events of inflammation in order.
Answer: 1)Margination
2)rolling
3)adhesion
4)transmigration
5)chemotaxis
6)activation
7)phagocytosis
◉ Why are new blood vessels leaky?
, Answer: they lack intercellular junctions
◉ What is the most important feature of inflammation?
Answer: -the recruit of leukocytes to affected tissues
◉ What is margination?
Answer: when blood is viscous due to inflammation WBCS are
pushed to the edges of vessels because of slow-moving RBC that are
small and therefore take the central region of the vessel
◉ What is another name for rouleaux-formation?
Answer: margination
◉ What is rolling?
Answer: WBCs temporarily adhere to endothelial cells via weak
interactions
◉ E-selections and P-selectins on the endothelial cells bind what
protein on leukocytes?
Answer: Sialyl-Lewis protein
◉ L-selectins on the leukocyte bind which receptor on the
endothelial cells?