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NUR 2502 EXAM 2 LATEST 2026/2027 |
PHARMACOLOGY – GALEN COLLEGE | EXPERT
VERIFIED | 75 VERIFIED Q&A | DETAILED RATIONALES
| NGN-ALIGNED | PASS GUARANTEED – A+ GRADED
Question 1
A nurse is reviewing the mechanism of action of metformin. Which of the following is the primary
mechanism?
A. Increases insulin secretion from pancreatic beta cells
B. Decreases hepatic glucose production and increases insulin sensitivity
C. Increases glucose reabsorption in the kidneys
D. Delays carbohydrate absorption in the intestines
Correct Answer: B
Rationale: Metformin primarily decreases hepatic gluconeogenesis and increases peripheral insulin
sensitivity.
Question 2
A nurse is reviewing the contraindications for metformin. Which of the following is a
contraindication?
A. Mild renal impairment
B. Severe renal impairment (eGFR <30 mL/min/1.73m²)
C. Hypertension
D. Obesity
Correct Answer: B
Rationale: Metformin is contraindicated in severe renal impairment due to lactic acidosis risk.
Question 3
A nurse is reviewing the mechanism of action of insulin. Which of the following is the primary
mechanism?
A. Decreases hepatic glucose production
B. Increases glucose uptake into cells
C. Increases glucose excretion
D. Delays carbohydrate absorption
Correct Answer: B
Rationale: Insulin increases glucose uptake into cells by promoting GLUT4 translocation.
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Question 4
A nurse is reviewing the types of insulin. Which of the following is a rapid-acting insulin?
A. Insulin glargine
B. Insulin lispro
C. NPH insulin
D. Insulin detemir
Correct Answer: B
Rationale: Insulin lispro (and aspart, glulisine) are rapid-acting with onset of 15-30 minutes.
Question 5
A nurse is reviewing the types of insulin. Which of the following is a long-acting insulin?
A. Insulin lispro
B. Regular insulin
C. Insulin glargine
D. NPH insulin
Correct Answer: C
Rationale: Insulin glargine (and detemir, degludec) are long-acting with no pronounced peak.
Question 6
A nurse is reviewing the mechanism of action of sulfonylureas. Which of the following is the primary
mechanism?
A. Decrease hepatic glucose production
B. Increase insulin secretion from pancreatic beta cells
C. Increase insulin sensitivity
D. Delay carbohydrate absorption
Correct Answer: B
Rationale: Sulfonylureas (e.g., glipizide) stimulate insulin secretion from beta cells.
Question 7
A nurse is reviewing the mechanism of action of thiazolidinediones (TZDs). Which of the following is
the primary mechanism?
A. Increase insulin secretion
B. Increase insulin sensitivity in peripheral tissues
C. Increase glucose excretion
D. Delay carbohydrate absorption
, 3
Correct Answer: B
Rationale: TZDs (e.g., pioglitazone) increase insulin sensitivity in peripheral tissues.
Question 8
A nurse is reviewing the mechanism of action of alpha-glucosidase inhibitors. Which of the following
is the primary mechanism?
A. Increase insulin secretion
B. Delay carbohydrate absorption in the intestines
C. Increase insulin sensitivity
D. Increase glucose excretion
Correct Answer: B
Rationale: Alpha-glucosidase inhibitors (e.g., acarbose) delay carbohydrate absorption.
Question 9
A nurse is reviewing the mechanism of action of SGLT2 inhibitors. Which of the following is the
primary mechanism?
A. Increase insulin secretion
B. Increase glucose excretion in the urine
C. Increase insulin sensitivity
D. Delay carbohydrate absorption
Correct Answer: B
Rationale: SGLT2 inhibitors (e.g., empagliflozin) increase glucose excretion in urine.
Question 10
A nurse is reviewing the mechanism of action of DPP-4 inhibitors. Which of the following is the
primary mechanism?
A. Increase insulin secretion
B. Increase incretin levels, increasing insulin secretion
C. Increase insulin sensitivity
D. Increase glucose excretion
Correct Answer: B
Rationale: DPP-4 inhibitors (e.g., sitagliptin) increase incretin levels, enhancing insulin secretion.
Question 11
A nurse is reviewing the mechanism of action of GLP-1 receptor agonists. Which of the following is
the primary mechanism?
NUR 2502 EXAM 2 LATEST 2026/2027 |
PHARMACOLOGY – GALEN COLLEGE | EXPERT
VERIFIED | 75 VERIFIED Q&A | DETAILED RATIONALES
| NGN-ALIGNED | PASS GUARANTEED – A+ GRADED
Question 1
A nurse is reviewing the mechanism of action of metformin. Which of the following is the primary
mechanism?
A. Increases insulin secretion from pancreatic beta cells
B. Decreases hepatic glucose production and increases insulin sensitivity
C. Increases glucose reabsorption in the kidneys
D. Delays carbohydrate absorption in the intestines
Correct Answer: B
Rationale: Metformin primarily decreases hepatic gluconeogenesis and increases peripheral insulin
sensitivity.
Question 2
A nurse is reviewing the contraindications for metformin. Which of the following is a
contraindication?
A. Mild renal impairment
B. Severe renal impairment (eGFR <30 mL/min/1.73m²)
C. Hypertension
D. Obesity
Correct Answer: B
Rationale: Metformin is contraindicated in severe renal impairment due to lactic acidosis risk.
Question 3
A nurse is reviewing the mechanism of action of insulin. Which of the following is the primary
mechanism?
A. Decreases hepatic glucose production
B. Increases glucose uptake into cells
C. Increases glucose excretion
D. Delays carbohydrate absorption
Correct Answer: B
Rationale: Insulin increases glucose uptake into cells by promoting GLUT4 translocation.
,2
Question 4
A nurse is reviewing the types of insulin. Which of the following is a rapid-acting insulin?
A. Insulin glargine
B. Insulin lispro
C. NPH insulin
D. Insulin detemir
Correct Answer: B
Rationale: Insulin lispro (and aspart, glulisine) are rapid-acting with onset of 15-30 minutes.
Question 5
A nurse is reviewing the types of insulin. Which of the following is a long-acting insulin?
A. Insulin lispro
B. Regular insulin
C. Insulin glargine
D. NPH insulin
Correct Answer: C
Rationale: Insulin glargine (and detemir, degludec) are long-acting with no pronounced peak.
Question 6
A nurse is reviewing the mechanism of action of sulfonylureas. Which of the following is the primary
mechanism?
A. Decrease hepatic glucose production
B. Increase insulin secretion from pancreatic beta cells
C. Increase insulin sensitivity
D. Delay carbohydrate absorption
Correct Answer: B
Rationale: Sulfonylureas (e.g., glipizide) stimulate insulin secretion from beta cells.
Question 7
A nurse is reviewing the mechanism of action of thiazolidinediones (TZDs). Which of the following is
the primary mechanism?
A. Increase insulin secretion
B. Increase insulin sensitivity in peripheral tissues
C. Increase glucose excretion
D. Delay carbohydrate absorption
, 3
Correct Answer: B
Rationale: TZDs (e.g., pioglitazone) increase insulin sensitivity in peripheral tissues.
Question 8
A nurse is reviewing the mechanism of action of alpha-glucosidase inhibitors. Which of the following
is the primary mechanism?
A. Increase insulin secretion
B. Delay carbohydrate absorption in the intestines
C. Increase insulin sensitivity
D. Increase glucose excretion
Correct Answer: B
Rationale: Alpha-glucosidase inhibitors (e.g., acarbose) delay carbohydrate absorption.
Question 9
A nurse is reviewing the mechanism of action of SGLT2 inhibitors. Which of the following is the
primary mechanism?
A. Increase insulin secretion
B. Increase glucose excretion in the urine
C. Increase insulin sensitivity
D. Delay carbohydrate absorption
Correct Answer: B
Rationale: SGLT2 inhibitors (e.g., empagliflozin) increase glucose excretion in urine.
Question 10
A nurse is reviewing the mechanism of action of DPP-4 inhibitors. Which of the following is the
primary mechanism?
A. Increase insulin secretion
B. Increase incretin levels, increasing insulin secretion
C. Increase insulin sensitivity
D. Increase glucose excretion
Correct Answer: B
Rationale: DPP-4 inhibitors (e.g., sitagliptin) increase incretin levels, enhancing insulin secretion.
Question 11
A nurse is reviewing the mechanism of action of GLP-1 receptor agonists. Which of the following is
the primary mechanism?
