NUR 660 EXAM 1 2026 HEALTHCARE DECISION
MAKING WORKBOOK SOLVED QUESTIONS
COMPILATION
◉ When a medication is added to a regimen for a synergistic effect,
the combined effect of the drugs is:
A. The sum of the effects of each drug individually
B. Greater than the sum of the effects of each drug individually
C. Less than the effect of each drug individually
D. Not predictable, as it varies with each individual.
Answer: B. Greater than the sum of the effects of each drug
individually
◉ Which of the following statements about bioavailability is true?
A. Bioavailability issues are especially important for drugs with
narrow therapeutic ranges or sustained release mechanisms.
B. All brands of a drug have the same bioavailability.
C. Drugs that are administered more than once a day have greater
bioavailability than drugs given once daily.
D. Combining an active drug with an inert substance does not affect.
Answer: A. Bioavailability issues are especially important for drugs
with narrow therapeutic ranges or sustained release mechanisms.
,◉ Which of the following statements about the major distribution
barriers (blood brain or fetal-placental) is true?
A. Water soluble and ionized drugs cross these barriers rapidly.
B. The blood-brain barrier slows the entry of many drugs into and
from brain cells.
C. The fetal-placental barrier protects the fetus from drugs taken by
the mother.
D. Lipid soluble drugs do not pass these barriers and are safe for
pregnant women.
Answer: B. The blood-brain barrier slows the entry of many drugs
into and from brain cells.
◉ Drugs are metabolized mainly by the liver via Phase I or Phase II
reactions. The purpose of both of these types of reactions is to:
A. Inactivate prodrugs before they can be activated by target tissues
B. Change the drugs so they can cross plasma membranes
C. Change drug molecules to a form that an excretory organ can
excrete
D. Make these drugs more ionized and polar to facilitate excretion.
Answer: C. Change drug molecules to a form that an excretory organ
can excrete
,◉ Once they have been metabolized by the liver, the metabolites
may be:
A. More active than the parent drug
B. Less active than the parent drug
C. Totally "deactivated" so that they are excreted without any effect
D. All of the above.
Answer: D. All of the above
◉ All drugs continue to act in the body until they are changed or
excreted. The ability of the body to excrete drugs via the renal
system would be increased by:
A. Reduced circulation and perfusion of the kidney
B. Chronic renal disease
C. Competition for a transport site by another drug
D. Unbinding a nonvolatile drug from plasma proteins.
Answer: D. Unbinding a nonvolatile drug from plasma proteins
◉ teady state is:
A. The point on the drug concentration curve when absorption
exceeds excretion
B. When the amount of drug in the body remains constant
C. When the amount of drug in the body stays below the MTC
D. All of the above.
, Answer: B. When the amount of drug in the body remains constant
◉ Two different pain meds are given together for pain relief. The
drug-drug interaction is:
A. Synergistic
B. Antagonistic
C. Potentiative
D. Additive.
Answer: D. Additive
◉ .Actions taken to reduce drug-drug interaction problems include
all of the following EXCEPT:
A. Reducing the dose of one of the drugs
B. Scheduling their administration at different times
C. Prescribing a third drug to counteract the adverse reaction of the
combination
D. Reducing the dosage of both drugs.
Answer: C. Prescribing a third drug to counteract the adverse
reaction of the combination
◉ Phase I oxidative-reductive processes of drug metabolism require
certain nutritional elements. Which of the following would reduce or
inhibit this process?
MAKING WORKBOOK SOLVED QUESTIONS
COMPILATION
◉ When a medication is added to a regimen for a synergistic effect,
the combined effect of the drugs is:
A. The sum of the effects of each drug individually
B. Greater than the sum of the effects of each drug individually
C. Less than the effect of each drug individually
D. Not predictable, as it varies with each individual.
Answer: B. Greater than the sum of the effects of each drug
individually
◉ Which of the following statements about bioavailability is true?
A. Bioavailability issues are especially important for drugs with
narrow therapeutic ranges or sustained release mechanisms.
B. All brands of a drug have the same bioavailability.
C. Drugs that are administered more than once a day have greater
bioavailability than drugs given once daily.
D. Combining an active drug with an inert substance does not affect.
Answer: A. Bioavailability issues are especially important for drugs
with narrow therapeutic ranges or sustained release mechanisms.
,◉ Which of the following statements about the major distribution
barriers (blood brain or fetal-placental) is true?
A. Water soluble and ionized drugs cross these barriers rapidly.
B. The blood-brain barrier slows the entry of many drugs into and
from brain cells.
C. The fetal-placental barrier protects the fetus from drugs taken by
the mother.
D. Lipid soluble drugs do not pass these barriers and are safe for
pregnant women.
Answer: B. The blood-brain barrier slows the entry of many drugs
into and from brain cells.
◉ Drugs are metabolized mainly by the liver via Phase I or Phase II
reactions. The purpose of both of these types of reactions is to:
A. Inactivate prodrugs before they can be activated by target tissues
B. Change the drugs so they can cross plasma membranes
C. Change drug molecules to a form that an excretory organ can
excrete
D. Make these drugs more ionized and polar to facilitate excretion.
Answer: C. Change drug molecules to a form that an excretory organ
can excrete
,◉ Once they have been metabolized by the liver, the metabolites
may be:
A. More active than the parent drug
B. Less active than the parent drug
C. Totally "deactivated" so that they are excreted without any effect
D. All of the above.
Answer: D. All of the above
◉ All drugs continue to act in the body until they are changed or
excreted. The ability of the body to excrete drugs via the renal
system would be increased by:
A. Reduced circulation and perfusion of the kidney
B. Chronic renal disease
C. Competition for a transport site by another drug
D. Unbinding a nonvolatile drug from plasma proteins.
Answer: D. Unbinding a nonvolatile drug from plasma proteins
◉ teady state is:
A. The point on the drug concentration curve when absorption
exceeds excretion
B. When the amount of drug in the body remains constant
C. When the amount of drug in the body stays below the MTC
D. All of the above.
, Answer: B. When the amount of drug in the body remains constant
◉ Two different pain meds are given together for pain relief. The
drug-drug interaction is:
A. Synergistic
B. Antagonistic
C. Potentiative
D. Additive.
Answer: D. Additive
◉ .Actions taken to reduce drug-drug interaction problems include
all of the following EXCEPT:
A. Reducing the dose of one of the drugs
B. Scheduling their administration at different times
C. Prescribing a third drug to counteract the adverse reaction of the
combination
D. Reducing the dosage of both drugs.
Answer: C. Prescribing a third drug to counteract the adverse
reaction of the combination
◉ Phase I oxidative-reductive processes of drug metabolism require
certain nutritional elements. Which of the following would reduce or
inhibit this process?
