ATI PN CUSTOM DOSAGE
CALCULATION ASSESSMENT | 100
QUESTIONS AND CORRECT ANSWERS
WITH RATIONALES | BRAND NEW
2025/2026 VERSION
Core Domains
1. Basic Dosage Calculations – Oral Medications, Liquid Medications, Capsules,
Tablets, Unit Conversions
2. Parenteral Dosage Calculations – Intramuscular, Subcutaneous, Intradermal
Injections, Reconstitution of Powders
3. Intravenous (IV) Flow Rate Calculations – mL/hr, gtt/min (Drip Rate), Infusion
Time, Drop Factor
4. Weight-Based Calculations – mg/kg, mcg/kg, Pediatric Dosing, Geriatric
Dosing, Body Surface Area (BSA)
5. Intravenous Infusion Calculations – Continuous Infusions, Intermittent
Infusions, Piggyback, IV Bolus
6. Enteral and Parenteral Nutrition – Tube Feedings, TPN, Caloric Calculations,
Formula Concentration
7. Heparin and Insulin Calculations – Units/mL, Sliding Scale, Bolus, Drip
Adjustments, Infusion Pumps
8. Pediatric and Neonatal Dosage Calculations – Weight-Based, Safe Dose Range,
Fluid Maintenance, Dilutions
9. Medication Administration – Reconstitution, Dilution, Concentration,
Conversions Between Systems
10. NGN – Clinical Judgment, Bow-Tie Case Studies, Extended Multiple Response,
Unfolding Cases, Prioritization
Introduction
This comprehensive practice examination is meticulously designed for practical
nursing students preparing for the ATI PN Custom Dosage Calculation
,Assessment. The examination covers all essential dosage calculation domains
required for successful program completion and NCLEX-PN readiness, including
basic calculations, parenteral dosing, IV flow rates, weight-based calculations,
heparin and insulin calculations, and pediatric dosing. Through a combination of
multiple-choice questions, Select-All-That-Apply (SATA), and Next Generation
NCLEX (NGN) style case studies, candidates will demonstrate their understanding
of pharmacological principles, clinical judgment, and safe medication
administration in diverse patient scenarios. Each question includes a detailed step-
by-step rationale explaining the correct answer and reinforcing the calculation
process. Successful completion of this examination demonstrates readiness for the
official ATI PN Dosage Calculation assessment and the NCLEX-PN licensure
examination.
SECTION ONE: QUESTIONS 1-100
1. A nurse is preparing to administer 500 mg of amoxicillin orally. Available is
amoxicillin 250 mg/5 mL. How many mL should the nurse administer per
dose?
A. 5 mL
B. 10 mL
C. 15 mL
D. 20 mL
B. 10 mL
RATIONALE: Use the formula: Desired / Available × Quantity = 500 mg / 250
mg × 5 mL = 2 × 5 mL = 10 mL. The nurse should administer 10 mL of
amoxicillin.
2. A nurse is preparing to administer 0.5 mg of digoxin PO. Available is
digoxin 0.25 mg/tablet. How many tablets should the nurse administer?
A. 0.5 tablets
B. 1 tablet
C. 2 tablets
D. 2.5 tablets
, C. 2 tablets
RATIONALE: Use the formula: Desired / Available = 0.5 mg / 0.25 mg = 2
tablets. The nurse should administer 2 tablets of digoxin.
3. A nurse is preparing to administer 1,000 mL of 0.9% sodium chloride IV to
infuse over 8 hours. The drop factor is 15 gtt/mL. Calculate the IV flow rate in
gtt/min.
A. 25 gtt/min
B. 31 gtt/min
C. 37 gtt/min
D. 42 gtt/min
B. 31 gtt/min
RATIONALE: Calculate: Total volume (1,000 mL) ÷ Total time (8 hr × 60
min/hr = 480 min) = 2.083 mL/min. Then multiply by drop factor: 2.083 mL/min ×
15 gtt/mL = 31.25 gtt/min = 31 gtt/min.
4. A nurse is preparing to administer 250 mg of ceftriaxone IM. Available is
ceftriaxone 500 mg powder. The directions state to add 2.1 mL of sterile water
to yield a concentration of 250 mg/mL. How many mL should the nurse
administer?
A. 0.5 mL
B. 1 mL
C. 1.5 mL
D. 2 mL
B. 1 mL
RATIONALE: Use the formula: Desired / Concentration = 250 mg / 250
mg/mL = 1 mL. The nurse should administer 1 mL of the reconstituted solution.
5. A nurse is preparing to administer 30 mg of phenobarbital IV. Available is
phenobarbital 65 mg/mL. How many mL should the nurse administer?
A. 0.3 mL
B. 0.46 mL
, C. 0.5 mL
D. 0.65 mL
B. 0.46 mL
RATIONALE: Use the formula: Desired / Available = 30 mg / 65 mg/mL =
0.4615 mL = 0.46 mL. The nurse should administer 0.46 mL of phenobarbital.
6. A nurse is preparing to administer 1,000 mL of lactated Ringer's IV to
infuse over 4 hours. The drop factor is 10 gtt/mL. Calculate the IV flow rate in
gtt/min.
A. 30 gtt/min
B. 35 gtt/min
C. 40 gtt/min
D. 42 gtt/min
D. 42 gtt/min
RATIONALE: Calculate: Total volume (1,000 mL) ÷ Total time (4 hr × 60
min/hr = 240 min) = 4.167 mL/min. Then multiply by drop factor: 4.167 mL/min ×
10 gtt/mL = 41.67 gtt/min = 42 gtt/min.
7. A nurse is preparing to administer 650 mg of acetaminophen PO. Available
is acetaminophen 325 mg/tablet. How many tablets should the nurse
administer?
A. 0.5 tablets
B. 1 tablet
C. 1.5 tablets
D. 2 tablets
D. 2 tablets
RATIONALE: Use the formula: Desired / Available = 650 mg / 325 mg = 2
tablets. The nurse should administer 2 tablets of acetaminophen.
8. A nurse is preparing to administer 0.25 mg of digoxin IM. Available is
digoxin 0.5 mg/2 mL. How many mL should the nurse administer?
CALCULATION ASSESSMENT | 100
QUESTIONS AND CORRECT ANSWERS
WITH RATIONALES | BRAND NEW
2025/2026 VERSION
Core Domains
1. Basic Dosage Calculations – Oral Medications, Liquid Medications, Capsules,
Tablets, Unit Conversions
2. Parenteral Dosage Calculations – Intramuscular, Subcutaneous, Intradermal
Injections, Reconstitution of Powders
3. Intravenous (IV) Flow Rate Calculations – mL/hr, gtt/min (Drip Rate), Infusion
Time, Drop Factor
4. Weight-Based Calculations – mg/kg, mcg/kg, Pediatric Dosing, Geriatric
Dosing, Body Surface Area (BSA)
5. Intravenous Infusion Calculations – Continuous Infusions, Intermittent
Infusions, Piggyback, IV Bolus
6. Enteral and Parenteral Nutrition – Tube Feedings, TPN, Caloric Calculations,
Formula Concentration
7. Heparin and Insulin Calculations – Units/mL, Sliding Scale, Bolus, Drip
Adjustments, Infusion Pumps
8. Pediatric and Neonatal Dosage Calculations – Weight-Based, Safe Dose Range,
Fluid Maintenance, Dilutions
9. Medication Administration – Reconstitution, Dilution, Concentration,
Conversions Between Systems
10. NGN – Clinical Judgment, Bow-Tie Case Studies, Extended Multiple Response,
Unfolding Cases, Prioritization
Introduction
This comprehensive practice examination is meticulously designed for practical
nursing students preparing for the ATI PN Custom Dosage Calculation
,Assessment. The examination covers all essential dosage calculation domains
required for successful program completion and NCLEX-PN readiness, including
basic calculations, parenteral dosing, IV flow rates, weight-based calculations,
heparin and insulin calculations, and pediatric dosing. Through a combination of
multiple-choice questions, Select-All-That-Apply (SATA), and Next Generation
NCLEX (NGN) style case studies, candidates will demonstrate their understanding
of pharmacological principles, clinical judgment, and safe medication
administration in diverse patient scenarios. Each question includes a detailed step-
by-step rationale explaining the correct answer and reinforcing the calculation
process. Successful completion of this examination demonstrates readiness for the
official ATI PN Dosage Calculation assessment and the NCLEX-PN licensure
examination.
SECTION ONE: QUESTIONS 1-100
1. A nurse is preparing to administer 500 mg of amoxicillin orally. Available is
amoxicillin 250 mg/5 mL. How many mL should the nurse administer per
dose?
A. 5 mL
B. 10 mL
C. 15 mL
D. 20 mL
B. 10 mL
RATIONALE: Use the formula: Desired / Available × Quantity = 500 mg / 250
mg × 5 mL = 2 × 5 mL = 10 mL. The nurse should administer 10 mL of
amoxicillin.
2. A nurse is preparing to administer 0.5 mg of digoxin PO. Available is
digoxin 0.25 mg/tablet. How many tablets should the nurse administer?
A. 0.5 tablets
B. 1 tablet
C. 2 tablets
D. 2.5 tablets
, C. 2 tablets
RATIONALE: Use the formula: Desired / Available = 0.5 mg / 0.25 mg = 2
tablets. The nurse should administer 2 tablets of digoxin.
3. A nurse is preparing to administer 1,000 mL of 0.9% sodium chloride IV to
infuse over 8 hours. The drop factor is 15 gtt/mL. Calculate the IV flow rate in
gtt/min.
A. 25 gtt/min
B. 31 gtt/min
C. 37 gtt/min
D. 42 gtt/min
B. 31 gtt/min
RATIONALE: Calculate: Total volume (1,000 mL) ÷ Total time (8 hr × 60
min/hr = 480 min) = 2.083 mL/min. Then multiply by drop factor: 2.083 mL/min ×
15 gtt/mL = 31.25 gtt/min = 31 gtt/min.
4. A nurse is preparing to administer 250 mg of ceftriaxone IM. Available is
ceftriaxone 500 mg powder. The directions state to add 2.1 mL of sterile water
to yield a concentration of 250 mg/mL. How many mL should the nurse
administer?
A. 0.5 mL
B. 1 mL
C. 1.5 mL
D. 2 mL
B. 1 mL
RATIONALE: Use the formula: Desired / Concentration = 250 mg / 250
mg/mL = 1 mL. The nurse should administer 1 mL of the reconstituted solution.
5. A nurse is preparing to administer 30 mg of phenobarbital IV. Available is
phenobarbital 65 mg/mL. How many mL should the nurse administer?
A. 0.3 mL
B. 0.46 mL
, C. 0.5 mL
D. 0.65 mL
B. 0.46 mL
RATIONALE: Use the formula: Desired / Available = 30 mg / 65 mg/mL =
0.4615 mL = 0.46 mL. The nurse should administer 0.46 mL of phenobarbital.
6. A nurse is preparing to administer 1,000 mL of lactated Ringer's IV to
infuse over 4 hours. The drop factor is 10 gtt/mL. Calculate the IV flow rate in
gtt/min.
A. 30 gtt/min
B. 35 gtt/min
C. 40 gtt/min
D. 42 gtt/min
D. 42 gtt/min
RATIONALE: Calculate: Total volume (1,000 mL) ÷ Total time (4 hr × 60
min/hr = 240 min) = 4.167 mL/min. Then multiply by drop factor: 4.167 mL/min ×
10 gtt/mL = 41.67 gtt/min = 42 gtt/min.
7. A nurse is preparing to administer 650 mg of acetaminophen PO. Available
is acetaminophen 325 mg/tablet. How many tablets should the nurse
administer?
A. 0.5 tablets
B. 1 tablet
C. 1.5 tablets
D. 2 tablets
D. 2 tablets
RATIONALE: Use the formula: Desired / Available = 650 mg / 325 mg = 2
tablets. The nurse should administer 2 tablets of acetaminophen.
8. A nurse is preparing to administer 0.25 mg of digoxin IM. Available is
digoxin 0.5 mg/2 mL. How many mL should the nurse administer?
