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Internal Medicine Boost Exam EOR | Questions & Verified Answers | Comprehensive Internal Medicine EOR Exam Review Study Guide PDF | 2026

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Prepare for your Internal Medicine Boost Exam EOR with this comprehensive study guide featuring exam questions and verified answers designed to strengthen clinical knowledge, diagnostic reasoning, and evidence-based patient management skills. This detailed review covers essential internal medicine topics including cardiovascular diseases, pulmonary disorders, gastrointestinal conditions, renal and electrolyte disorders, endocrine diseases, infectious diseases, hematology and oncology, rheumatology, neurology, preventive medicine, critical care, clinical pharmacology, diagnostic testing, laboratory interpretation, differential diagnosis, treatment principles, and common clinical scenarios. Ideal for physician assistant students, PA clinical-year learners, internal medicine students, medical trainees, and healthcare professionals, this resource is perfect for preparing for EOR examinations, practice tests, board-style questions, clinical assessments, and comprehensive internal medicine reviews while improving knowledge retention, strengthening clinical reasoning, and maximizing exam readiness.

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Internal Medicine Boost Exam EOR
A 40-year-old man presents to the clinic with burning C peptic ulcer disease
abdominal pain that extends from his navel to his chest for
the past couple of days. Loss of appetite is his only other
complaint. Physical exam is normal. He smokes one pack
of cigarettes per day and drinks two to three beers daily.
An ulceration in the gastric lining is seen on upper
endoscopy. What is the most likely diagnosis?
A Barrett esophagus
B Gastric cancer
C Peptic ulcer disease
D Ulcerative colitis


A 45-year-old hypertensive man presents with a persistent, D lisinopril
dry cough. He is currently taking clonidine 0.1 mg three
times daily, amlodipine 10 mg daily, lisinopril 40 mg daily,
and aspirin 81 mg daily. Which of his medications is most
likely contributing to his symptoms?
AAmlodipine
BAspirin
CClonidine
DLisinopril


A 44-year-old woman with a history of chronic pancreatitis B fasting glucose level
secondary to alcohol use presents to the clinic for routine
care. She reports her symptoms are well-controlled. She
was last seen a year ago. Which of the following tests is
indicated for this patient?
AAbdominal ultrasound
BFasting glucose level
CMagnetic resonance cholangiopancreatography
DSerum amylase and lipase


what is the triad for WPW short PR
wide QRS
delta wave


Which of the following best represents an appropriate lipid C lipid profile beginning at age 35
screening protocol for an adult man with no other
cardiovascular risk factors?
ALipid profile beginning at age 20
BLipid profile beginning at age 30
CLipid profile beginning at age 35
DLipid profile beginning at age 40


Which of the following physical exam findings is most C substernal chest pain associated with a new third heart sound
indicative of angina pectoris?
ALeft-sided chest pain associated with a dermatomal
vesicular rash
BReproducible chest pain on chest wall palpation
CSubsternal chest pain associated with a new third heart
sound
DSubsternal chest pain associated with decreased heart
sounds and jugular venous distention


A 67-year-old man presents to the emergency department D theophylline 200 mg per oral route
with an acute exacerbation of chronic bronchitis and is
hospitalized. His home medications include inhaled
albuterol and ipratropium. Administration of which of the
following is contraindicated?
AAlbuterol 2.5 mg per nebulizer
BLevofloxacin 500 mg IV
CMethylprednisolone 125 mg IV
DTheophylline 200 mg per oral route

, Internal Medicine Boost Exam EOR
A 58-year-old woman, newly diagnosed with Sjӧgren A cevimeline
syndrome, returns to the clinic complaining of worsening
dry mouth. At her last visit, you recommended she take
frequent drinks of water throughout the day and try various
over-the-counter products as well as artificial saliva, which
she did, but her mouth symptoms persist. What is the most
likely medication you would start her on?
ACevimeline
BCyclosporine drops
CLow-dose prednisone
DSulfasalazine


what are 3 best treatments for CAP without comorbidities amoxicillin OR
or risk factors for MRSA or Paeruginosa doxycycline OR
macrolide


A 24-year-old woman presents with complaints of A central diabetes insipidus
excessive thirst over the past several weeks. She also
notes waking up in the middle of the night to urinate. She
recently underwent transsphenoidal resection of a pituitary
adenoma. Which of the following is the most likely
diagnosis?
ACentral diabetes insipidus
BNephrogenic diabetes insipidus
CPrimary polydipsia
DType 2 diabetes mellitus


A 25-year-old man presents to the emergency department A cardiac tamponade
with a knife wound in his chest, located to the left of the
sternum. He is minimally responsive and pale. His blood
pressure is 80/60 mm Hg and his heart rate is 150 bpm.
He has prominent jugular venous distention and his
systolic blood pressure drops about 10 mm Hg with
inspiration. Breath sounds are normal. What is the most
likely diagnosis?
ACardiac tamponade
BPericarditis
CPneumothorax
DPulmonary embolism


In the treatment of Alzheimer disease, which of the B memantine
following pharmacologic treatment options is found to be
neuroprotective?
ADonepezil
BMemantine
CSelegiline
DVitamin E


A 60-year-old man with a history of hypertension, B ezetimibe
hyperlipidemia, and heavy tobacco use has been
compliant with his 80 mg dose of atorvastatin for the past
twelve months. His current total cholesterol measurement
is 220 mg/dL. You decide to add another lipid lowering
agent. Which of the following drugs has proven beneficial
for the prevention of adverse cardiovascular disease
events when added to statin therapy?
ACholestyramine
BEzetimibe
CFenofibrate
DNiacin


Which of the following is the recommended first-line A lorazepam
treatment of generalized convulsive status epilepticus?
ALorazepam
BPhenobarbital
CPropofol
DTopiramate

, Internal Medicine Boost Exam EOR
A 70-year-old male is beginning treatment for peripheral A aspirin, cilostazol, rosuvastatin, smoking cessation, and structured exercise
vascular disease. He has a 50 pack year smoking history
and is currently smoking one pack per day. His ankle-
brachial index is 0.76, and his dorsalis pedis pulses are
diminished bilaterally. His main complaint is a reduction in
his ability to continue morning walks with his brother due to
pain in his calves that resolves with rest. Which of the
following is the most appropriate therapy?

AAspirin, cilostazol, rosuvastatin, smoking cessation, and
structured exercise
BAspirin, rosuvastatin, smoking cessation, and surgical
referral
CClopidogrel, endovascular reperfusion, rosuvastatin, and
smoking cessation
DClopidogrel, structured exercise, and smoking cessation


A 30-year-old woman presents to the clinic with weight D hypothyroidism
gain, fatigue, and constipation. She has gained 15 lbs
during the past three weeks despite no change in her diet.
Her heart rate is 50/minute and her blood pressure is
145/95 mm Hg. Physical examination reveals cool and
pale skin, periorbital edema, and hair loss. Which of the
following is the most likely diagnosis?
AHyperparathyroidism
BHyperthyroidism
CHypoparathyroidism
DHypothyroidism


Which of the following laboratory values is most likely to be A serum glucose
elevated in a patient with hypertonic hyponatremia?
ASerum glucose
BSerum potassium
CSerum sodium
DSerum triglycerides


A 30-year-old woman presents to the ED for evaluation of A antiphospholipid antibody syndrome
left lower extremity swelling for the past day. She has not
had any associated injury, recent travel, or immobilization.
Her medical history is notable for a deep vein thrombosis
in the right lower extremity diagnosed 5 years prior and
treated with anticoagulation. She also had an unexplained
miscarriage at 14 weeks of gestation 2 years ago. Doppler
ultrasonography is performed today in the ED, revealing a
left lower extremity deep venous thrombosis. Complete
blood count is notable for a platelet count of 110,000/mcL.
Which of the following is the most likely underlying
diagnosis?
AAntiphospholipid antibody syndrome
BAtrial myxoma
CHeterozygous factor V Leiden
DMalignancy associated thrombosis


A 24-year-old man presents to the emergency department A acute cholangitis
with fever and chills, right upper quadrant pain, and
jaundice. Abdominal ultrasound shows dilation of the
common bile duct. What is the most likely diagnosis?
AAcute cholangitis
BAcute cholecystitis
CAcute hepatitis
DCholelithiasis

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