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RN Pharmacology A | Practice Questions, Answers & Study Guide 2026/2027

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RN Pharmacology A Exam Prep | Practice Test, Questions & Comprehensive Nursing Pharmacology Review

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RN Pharmacology A Exam Questions And
Answers
Which of the following medications is known to cause orange-colored urine? -
CORRECT ANSWER-phenazopyridine (Pyridium)

You are ordered to give digoxin. Your patient's vital signs are as follows: Blood
Pressure 130/75, Temp 97.9 oral, HR 52, O2 Sat 100% room air. What should
you do next? - CORRECT ANSWER-Hold digoxin and call the provider

Normal Saline (NS) is the solution of choice over D5W when preparing to
administer a blood transfusion because: - CORRECT ANSWER-Normal Saline is
an isotonic solution and prevents cell hemolysis

Patient is to receive 5mg/kg of medication. Patient weighs 80kg. How much
would you administer? - CORRECT ANSWER-400mg

Your patient taking digoxin (Lanoxin) has an AM Potassium level of 3.0. This
level may: - CORRECT ANSWER-Increase risk of digoxin toxicity

The patient is diagnosed with multiple myeloma. The physician has ordered
cyclophosphamide (Cytoxan). Which instruction should be given to the patient? -
CORRECT ANSWER-Increase daily water intake

Which of the following medications will crystalize when mixed with D5NS? -
CORRECT ANSWER-phenytoin (Dilantin)

Which of the following medications should be questioned by the nurse, if ordered
by the provider to treat a patient's complaint of nausea and vomiting? -
CORRECT ANSWER-famotidine (Pepcid)

Your patient has an epidural infusing hydromorphone with bupivacaine at 6ml/hr
continuously. The patient's blood pressure at the beginning of your shift was
92/58 with a heart rate of 68. You noticed the patient's blood pressures have

,been around 130/70. What should you do FIRST? - CORRECT ANSWER-Check
infusion rate to confirm 6ml/hr, then notify anesthesia provider

The dosage of which drug must be tapered off slowly to prevent acute adrenal
insufficiency? - CORRECT ANSWER-prednisone (Deltasone)

When teaching a new nurse on how to administer IV push furosemide (Lasix),
you emphasize that it should be given over two minutes to avoid: - CORRECT
ANSWER-tinnitus

A nurse is caring for a patient with hyperparathyroidism and notes that the
patient's serum calcium level is 13mg/dl. Which medication should the nurse
prepare to administer as prescribed to the patient? - CORRECT
ANSWER-calcintonin (Miacalcin)

A patient has a prescription to take Guaifenesin (Mucinex) every 4 hours, as
needed. The nurse determines that the patient understands the MOST effective
use of the medication if the patient states that he or she will: - CORRECT
ANSWER-take the medication with a full glass of water

Acetylsalicylic acid (Aspirin) has which of the following pharmacological effects? -
CORRECT ANSWER-Anti-inflammatory, anti-pyretic, decrease platelet
aggregation

Your patient is to receive 2 G vancomycin over 2 hours. The medication comes in
from the pharmacy as 2 G Vancomycin in 250ml normal saline. At what rate will
the IV medication run? - CORRECT ANSWER-125ml/hr

Sildenafil (Viagra) is prescribed to treat a patient with erectile dysfunction. A
nurse reviews the patient's medical record and would question the prescription if
which of the following is noted in the history? - CORRECT ANSWER-Use of
nitroglycerin

While delivering the lunch tray of a patient who is taking warfarin (Coumadin), the
nurse notices diversity of food items. Which of the following foods would be a
concern? - CORRECT ANSWER-Spinach

,Your patient is receiving vancomycin (Vancocin) 500mg IV every 12 hours. As a
nurse, you understand that the PRIMARY rationale for monitoring serum levels of
vancomycin is that: - CORRECT ANSWER-It can cause nephrotoxicity

Convert 1.2 milligrams to micrograms - CORRECT ANSWER-1200 mcg

When caring for a patient with a central line who is receiving TPN, what is the
MOST important action on the part of the nurse to prevent CLABSI? - CORRECT
ANSWER-wrong answer: Change IV tubing and perform CVC dressing on
patient every 36 hours

You are caring for a patient with diabetes. Humalog insulin is ordered via sliding
scale AC and HS. When is the best time to administer Humalog insulin? -
CORRECT ANSWER-15 minutes before meal arrives

A provider orders one liter of NS to be infused over four hours. At what rate
would you set the IV pump? - CORRECT ANSWER-250ml/hr

Which medication is used to treat iron toxicity? - CORRECT
ANSWER-deferoxamine (Digibind)

Your patient presents with CHF and has a Potassium level of 5.8. Which diuretic
do you anticipate being ordered by the provider? - CORRECT
ANSWER-bumetanide (Bumex)

Your patient is on a Morphine PCA after a recent exploratory surgery. While
doing your rounds, you notice that your patient is slumped over, unresponsive,
with delayed and slow respirations. You suspect narcotic overdose. Which
reversal medication would you administer? - CORRECT ANSWER-naloxone
(Narcan)

A patient's capillary blood glucose reading is 33mg/dl. Which of the following
medications will the nurse administer if the patient is unable to tolerate PO? -
CORRECT ANSWER-Dextrose 50% IV push

When a patient has pernicious anemia, the nurse would expect to give them: -
CORRECT ANSWER-Vitamin B12

, RN Pharmacology A Relias

what medication is a leukotriene receptor antagonist? - CORRECT
ANSWER-Montelukast

Which statement made by a person regarding hydrochlorothiazide (HCTZ) is
correct? - CORRECT ANSWER-I should take extra care when standing up or
changing positions.

A 250mg dose of an oral medication has been ordered. The medication is
supplied only in 100mg tablets. How many tablets would you administer? -
CORRECT ANSWER-2.5

What medication is considered a potassium-sparing diuretic? - CORRECT
ANSWER-spironolactione (Aldactone)

You receive report from the off-going nurse that the person being cared for just
received their fourth dose of IV vancomycin that was administered over 30
minutes. Upon assessment of them, you notice their face and neck are red and
they are itching all over. What would you suspect? - CORRECT ANSWER-Red
man syndrome due to a rapid infusion rate.

Which of the following would you question if prescribed for a person taking
sildenafil (Viagra? - CORRECT ANSWER-nitroglycerin

You are caring for a person with a capillary blood glucose of 33 mg/dL and they
are unable to tolerate oral intake. Which of the following would you administer? -
CORRECT ANSWER-dextrose 50% IV push

A physician's written order for the person you are caring for is as follows: Insulin
glargine (Lantus), 10 U, subQ QD. What changes would you suggest for safety
and to avoid the use of "do not use" abbreviations? - CORRECT ANSWER-spell
out units and daily

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