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Pharmacology HESI Practice Exam Questions & Answers | HESI Pharmacology Study Guide & Exam Prep 2026/2027

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Pharmacology HESI Practice Exam Questions & Answers | HESI Pharmacology Study Guide & Exam Prep 2026/2027

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Pharm HESI Practice Exam Latest
update(QUESTIONS AND ANSWERS) 2024

A 43-year-old female client is prescribed thyroid replacement hormone following a
thyroidectomy. Which adverse effects should the nurse instruct the client to report immediately
to the healthcare provider?

A. Tinnitus and dizziness.
B. Tachycardia and chest pain.
C. Dry skin and intolerance to cold.
D. Weight gain and increased appetite. - ANS-B. Tachycardia and chest pain.

A Category X drug is prescribed for a young adult female client. Which instruction is most
important for the nurse to teach this client?

A. Use a reliable form of birth control.
B. Avoid exposure to ultra violet light.
C. Refuse this medication if planning pregnancy.
D. Abstain from intercourse while on this drug. - ANS-A. Use a reliable form of birth control.

A client asks the nurse if glipizide (Glucotrol) is an oral insulin. Which response should the nurse
provide?

A. "Yes, it is an oral insulin and has the same actions and properties as intermediate insulin."
B. "Yes, it is an oral insulin and is distributed, metabolized, and excreted in the same manner as
insulin."
C. "No, it is not an oral insulin and can be used only when some beta cell function is present."
D. "No, it is not an oral insulin, but it is effective for those who are resistant to injectable
insulins." - ANS-C. "No, it is not an oral insulin and can be used only when some beta cell
function is present."

A client being discharged home is prescribed an antibiotic with a dosage three times higher than
it was administered when the client was in the hospital. Which route of administration should the
nurse anticipate will be prescribed for the greatest first-pass effect?

A. Oral.
B. Sublingual.
C. Intravenous.
D. Subcutaneous. - ANS-A. Oral.

, A client being discharged is prescribed warfarin for the treatment following a pulmonary
embolism. Which diagnostic test should the nurse instruct the client to receive once a month?

A. Perfusion scan.
B. Prothrombin Time (PT).
C. Activated partial thromboplastin (aPTT).
D. Serum Coumadin level (SCL). - ANS-B. Prothrombin Time (PT).

A client being treated for hyperthyroidism with propylthiouracil (PTU) asks the nurse how the
medication works. Which is the best response to give the client?

A. It decreases the amount of thyroid-stimulating hormone circulating in the blood.
B. It increases the amount of thyroid-stimulating hormone circulating in the blood.
C. It enhances the amount of T4 and diminishes the amount of T3 produced by the thyroid.
D. It inhibits the synthesis of T3 and T4 by the thyroid gland. - ANS-D. It inhibits the synthesis of
T3 and T4 by the thyroid gland.

A client has a continuous IV infusion of dopamine (Intropin) and an IV of normal saline at 50
mL/hour. The nurse notes that the client's urinary output has been 20 mL/hour for the last 2
hours. Which intervention should the nurse initiate?

A. Stop the infusion of dopamine.
B. Change the normal saline to a keep open rate.
C. Replace the urinary catheter.
D. Notify the healthcare provider of the urinary output. - ANS-D. Notify the healthcare provider of
the urinary output.

A client is admitted to the hospital for a new onset of supraventricular tachycardia (SVT) and is
prescribed digoxin. For which laboratory finding should the nurse notify the healthcare provider
immediately?

A. Potassium level of 3.1 mEq/L.
B. Sodium level of 132 mEq/L.
C. Calcium level of 8.6 mg/dL.
D. Magnesium level of 1.2 mEq/L. - ANS-A. Potassium level of 3.1 mEq/L.

A client is admitted to the hospital for diagnostic testing for possible myasthenia gravis. The
nurse prepares for intravenous administration of edrophonium chloride (Tensilon). What is the
expected outcome for this client following administration of this pharmacologic agent?

A. Progressive difficulty with swallowing.
B. Decreased respiratory effort.
C. Improvement in generalized fatigue.
D. Decreased muscle weakness. - ANS-D. Decreased muscle weakness.

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