CMA Exam Study Guide 2026/2027 | 80+ Questions & Answers | Medication Administration, Phlebotomy, EKG, Vital Signs, OSHA, CLIA & Infection Control | Certified Medical Assistant

This CMA Exam Study Guide 2026/2027 is an 11-page exam-preparation resource containing 80+ questions, answers, definitions and clinical review points for Certified Medical Assistant students and candidates. It concentrates on high-yield medical assisting competencies including the rights of medication administration, phlebotomy and venipuncture, injection routes and angles, EKG fundamentals, vital signs, infection prevention, OSHA and bloodborne-pathogen safety, CLIA and point-of-care testing, specimen collection, patient positioning, medical terminology, consent, HIPAA, laboratory procedures and basic emergency response. The cover page identifies the document as a CMA exam study guide for 2026/2027 with questions and answers. The medication-administration material begins with the 10 rights of medication administration: right patient, medication, dose, time, route, education, refusal, assessment, evaluation and documentation. Students also review medication safety through expiration-date checks and common administration routes, including sublingual and transdermal medications. Injection technique is reinforced through questions covering 15-degree intradermal, 90-degree intramuscular and 45-degree subcutaneous administration, providing concise recall practice for common clinical skills. A major portion focuses on phlebotomy, specimen collection and laboratory procedures. Topics include butterfly or winged collection sets for fragile veins, patient preparation during blood collection, post-venipuncture observation, needlestick reporting, throat specimens for streptococcal testing, clean-catch urine specimens and urine labeling. The guide also reviews blood collection tubes and laboratory departments, including yellow culture tubes, light-blue coagulation tubes, chemistry tubes and purple hematology tubes. Point-of-care testing, quality control, glucose-tolerance testing and pregnancy testing are also included. The EKG and cardiovascular assessment content covers the ST segment, calculation of heart rate from EKG boxes, potential motion or tremor artifacts and appropriate patient preparation. Vital-sign review includes temperature, pulse, blood pressure and respiration, as well as apical pulse assessment in infants, Korotkoff sounds and blood-pressure recording in millimeters of mercury. Students also review the relationship between systolic and diastolic pressure and common clinical positions used when patients experience particular symptoms. The document places considerable emphasis on infection control, OSHA requirements and workplace safety. Students review medical versus surgical asepsis, sterilization, hazardous and biohazardous waste, tuberculosis airborne precautions, disinfectants, nosocomial infections, bloodborne-pathogen training and immediate reporting of occupational needlestick exposure. It also defines OSHA and discusses its role in establishing and enforcing workplace safety standards. The CLIA and diagnostic-testing material introduces the Clinical Laboratory Improvement Amendments and their relevance to human laboratory testing in the United States. The guide connects laboratory regulation with point-of-care testing and quality-control procedures designed to support reliable results. Other diagnostic concepts include spirometry for measuring inspired and expired air volumes, the Snellen chart for visual acuity and the Ishihara test for red-green color-vision deficiencies. Patient positioning and routine clinical procedures receive additional attention. The questions cover Sims, Fowler's, lithotomy-related concepts and Trendelenburg positioning, alongside rectal temperature measurement, pulmonary testing, patient forms and handling delays in the medical office. The study guide therefore combines hands-on clinical knowledge with practical patient-flow and communication scenarios commonly encountered by medical assistants. The final sections reinforce medical terminology, pathology, patient documentation and legal concepts. Terms include nephrectomy, metastasis, atrophy, hematoma, thrombus, hemophilia, amenorrhea, dysmenorrhea, enteropexy and presbyopia. Students distinguish subjective from objective patient information and review informed, implied and written consent, privacy, HIPAA, assault and battery. These topics broaden the guide beyond procedural skills to include the legal, ethical and documentation responsibilities associated with medical assisting. Relevant students: This study guide is most relevant to CMA candidates, Certified Medical Assistant students, medical assisting program students, clinical medical assistant trainees and allied-health learners seeking rapid question-and-answer review before an exam. It is especially useful for students revising medication administration, phlebotomy, EKG, vital signs, laboratory procedures, OSHA, CLIA, infection control, patient positioning and medical terminology. Some statements in the document are simplified, outdated, misspelled or potentially inaccurate, so the resource is best used for active recall alongside current certification materials and authoritative clinical guidelines rather than as a sole clinical reference. 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