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I-HUMAN DERMATOLOGY CASES 70 QUESTIONS EXAM
2026 QUESTIONS LATEST VERSION QUESTIONS AND
ANSWERS
i-Human Dermatology Cases: 70 Practice Questions with Rationales
DOMAIN 1: HISTORY OF PRESENT ILLNESS & OLD CARTS FRAMEWORK (15
Questions)
1. The nurse is interviewing an i-Human patient with a skin rash. Which of the
following is the MOST appropriate question to assess the "Character" of the rash?
A) "When did your rash start?"
B) "Is your rash raised, flat, or blister-like?"
C) "Does anything make your rash worse?"
D) "Where exactly is the rash located?"
Answer: B) "Is your rash raised, flat, or blister-like?"
Rationale: The OLD CARTS framework includes Character as a key component of symptom
description. Character describes the quality or nature of the symptom—in this case, the
morphology of the rash (maculopapular, vesicular, etc.). Onset (A), Aggravating factors (C),
and Location (D) are separate components of OLD CARTS .
2. In the OLD CARTS framework, a patient reports that their rash started "about 36
hours ago." This corresponds to which component?
A) Location
B) Duration
C) Onset
D) Timing
Answer: C) Onset
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Rationale: Onset in OLD CARTS refers to when the symptom first started. In the Victoria
Lewis i-Human case, the rash began approximately 36 hours ago, which is the onset .
3. An i-Human patient with a rash reports that symptoms are "worse after applying a
new lotion." The nurse should document this under which OLD CARTS component?
A) Aggravating factors
B) Alleviating factors
C) Timing
D) Associated symptoms
Answer: A) Aggravating factors
Rationale: Aggravating factors are conditions that make the symptom worse. In the Victoria
Lewis case, the rash developed after exposure to new lotion, new detergent, and hiking
(potential poison ivy), making these important aggravating factors .
4. In the i-Human Victoria Lewis case, the patient reports a pruritic rash that is "itchy,
red, slightly swollen, and somewhat tender." This symptom cluster is MOST consistent
with:
A) Atopic dermatitis
B) Allergic contact dermatitis
C) Tinea corporis
D) Psoriasis
Answer: B) Allergic contact dermatitis
Rationale: This presentation is classic for allergic contact dermatitis. In the Victoria Lewis
case, the rash was pruritic, erythematous, maculopapular, with no systemic symptoms, and
developed after exposure to new lotion, hiking (poison ivy), and new detergent .
5. A 25-year-old i-Human patient reports a rash that began 24-48 hours after exposure
to a new lotion and hiking in wooded areas. The MOST likely diagnosis is:
A) Atopic dermatitis
B) Allergic contact dermatitis
C) Tinea corporis
D) Urticaria
Answer: B) Allergic contact dermatitis
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Rationale: The temporal relationship (24-48 hours after exposure), distribution on exposed
areas (arms, legs, neck), and morphology (erythematous, maculopapular, pruritic) are
classic for allergic contact dermatitis. In i-Human cases, exposure history is a key diagnostic
clue .
6. An i-Human patient with a rash reports "intense itching, worse at night." The nurse
should recognize that this symptom is characteristic of:
A) Allergic contact dermatitis
B) Atopic dermatitis with possible scabies
C) Tinea corporis
D) Urticaria
Answer: B) Atopic dermatitis with possible scabies
Rationale: Intense pruritus, especially worse at night, is characteristic of atopic dermatitis
and scabies. In the i-Human pediatric case, the 13-year-old with atopic dermatitis reported
itching worse at night, with flexural involvement .
7. In the OLD CARTS framework, a patient reports that their rash is "on my arms,
legs, and neck." This corresponds to which component?
A) Location
B) Radiation
C) Character
D) Severity
Answer: A) Location
Rationale: Location in OLD CARTS refers to where the symptom is found. In the Victoria
Lewis case, the rash was on exposed areas (arms, legs, neck), which is consistent with
contact dermatitis .
8. A patient reports that their rash is "worse with heat and sweating." The nurse should
document this under which OLD CARTS component?
A) Aggravating factors
B) Alleviating factors
C) Timing
D) Associated symptoms
Answer: A) Aggravating factors
I-HUMAN DERMATOLOGY CASES 70 QUESTIONS EXAM
2026 QUESTIONS LATEST VERSION QUESTIONS AND
ANSWERS
i-Human Dermatology Cases: 70 Practice Questions with Rationales
DOMAIN 1: HISTORY OF PRESENT ILLNESS & OLD CARTS FRAMEWORK (15
Questions)
1. The nurse is interviewing an i-Human patient with a skin rash. Which of the
following is the MOST appropriate question to assess the "Character" of the rash?
A) "When did your rash start?"
B) "Is your rash raised, flat, or blister-like?"
C) "Does anything make your rash worse?"
D) "Where exactly is the rash located?"
Answer: B) "Is your rash raised, flat, or blister-like?"
Rationale: The OLD CARTS framework includes Character as a key component of symptom
description. Character describes the quality or nature of the symptom—in this case, the
morphology of the rash (maculopapular, vesicular, etc.). Onset (A), Aggravating factors (C),
and Location (D) are separate components of OLD CARTS .
2. In the OLD CARTS framework, a patient reports that their rash started "about 36
hours ago." This corresponds to which component?
A) Location
B) Duration
C) Onset
D) Timing
Answer: C) Onset
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Rationale: Onset in OLD CARTS refers to when the symptom first started. In the Victoria
Lewis i-Human case, the rash began approximately 36 hours ago, which is the onset .
3. An i-Human patient with a rash reports that symptoms are "worse after applying a
new lotion." The nurse should document this under which OLD CARTS component?
A) Aggravating factors
B) Alleviating factors
C) Timing
D) Associated symptoms
Answer: A) Aggravating factors
Rationale: Aggravating factors are conditions that make the symptom worse. In the Victoria
Lewis case, the rash developed after exposure to new lotion, new detergent, and hiking
(potential poison ivy), making these important aggravating factors .
4. In the i-Human Victoria Lewis case, the patient reports a pruritic rash that is "itchy,
red, slightly swollen, and somewhat tender." This symptom cluster is MOST consistent
with:
A) Atopic dermatitis
B) Allergic contact dermatitis
C) Tinea corporis
D) Psoriasis
Answer: B) Allergic contact dermatitis
Rationale: This presentation is classic for allergic contact dermatitis. In the Victoria Lewis
case, the rash was pruritic, erythematous, maculopapular, with no systemic symptoms, and
developed after exposure to new lotion, hiking (poison ivy), and new detergent .
5. A 25-year-old i-Human patient reports a rash that began 24-48 hours after exposure
to a new lotion and hiking in wooded areas. The MOST likely diagnosis is:
A) Atopic dermatitis
B) Allergic contact dermatitis
C) Tinea corporis
D) Urticaria
Answer: B) Allergic contact dermatitis
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Rationale: The temporal relationship (24-48 hours after exposure), distribution on exposed
areas (arms, legs, neck), and morphology (erythematous, maculopapular, pruritic) are
classic for allergic contact dermatitis. In i-Human cases, exposure history is a key diagnostic
clue .
6. An i-Human patient with a rash reports "intense itching, worse at night." The nurse
should recognize that this symptom is characteristic of:
A) Allergic contact dermatitis
B) Atopic dermatitis with possible scabies
C) Tinea corporis
D) Urticaria
Answer: B) Atopic dermatitis with possible scabies
Rationale: Intense pruritus, especially worse at night, is characteristic of atopic dermatitis
and scabies. In the i-Human pediatric case, the 13-year-old with atopic dermatitis reported
itching worse at night, with flexural involvement .
7. In the OLD CARTS framework, a patient reports that their rash is "on my arms,
legs, and neck." This corresponds to which component?
A) Location
B) Radiation
C) Character
D) Severity
Answer: A) Location
Rationale: Location in OLD CARTS refers to where the symptom is found. In the Victoria
Lewis case, the rash was on exposed areas (arms, legs, neck), which is consistent with
contact dermatitis .
8. A patient reports that their rash is "worse with heat and sweating." The nurse should
document this under which OLD CARTS component?
A) Aggravating factors
B) Alleviating factors
C) Timing
D) Associated symptoms
Answer: A) Aggravating factors
